Health and Me

Tanya Dutt

Could These Common Cancer Drugs Could Be The Key To Reversing And Treating Alzheimer’s?

Alzheimer’s has long been one of medicine’s most frustrating puzzles. Despite decades of research and billions in funding, we still don’t have a cure, and the handful of approved treatments offer only modest relief. But now, scientists from UC San Francisco and the Gladstone Institutes may have uncovered an unlikely lead: two cancer drugs that could potentially reverse Alzheimer’s-related brain changes.

The findings, published in the journal Cell, are generating buzz for one big reason: they didn’t come from years of trial-and-error drug development, but from a computational deep dive into big data, gene expression, and real-world patient records. The research team didn’t set out to find a miracle—yet what they discovered might just change the way we treat one of the world’s most devastating neurological diseases.

To understand how this started, let’s zoom in on what actually happens in the Alzheimer’s brain.

In people with the disease, neurons and glial cells undergo dramatic shifts in gene expression—the biological instructions that tell a cell how to function. These changes disrupt memory, cognition, and eventually basic bodily functions.

Instead of targeting a single protein (like beta-amyloid plaques, the long-standing focus in Alzheimer’s research), UCSF scientists took a broader approach. They analyzed single-cell gene expression data from brain tissue donated by individuals with and without Alzheimer’s. This allowed them to pinpoint the exact genetic changes happening in both neurons and glia during disease progression.

Then came the twist: they used a database known as the Connectivity Map—essentially a chemical encyclopedia—to match those Alzheimer’s gene expression patterns against thousands of existing drugs. The goal? To find drugs that reverse those patterns.

Out of 1,300 drugs studied, 86 had the potential to reverse Alzheimer’s-associated gene changes in at least one brain cell type. Only 25 affected multiple cell types. And of those, just 10 were already FDA-approved.

That’s how two unexpected candidates—letrozole (a breast cancer drug) and irinotecan (used for colon and lung cancers)—emerged as frontrunners.

The team didn’t stop at computer modeling. They turned to electronic health records, combing through anonymized data from 1.4 million patients over the age of 65 in the UC Health Data Warehouse.

What they found was striking: patients treated with letrozole or irinotecan had lower rates of Alzheimer’s. This wasn’t a controlled trial, but it was a strong signal—and one worth testing further.

So the team brought the drugs into the lab, using mice genetically engineered to develop Alzheimer’s-like symptoms. As the mice aged and memory declined, the researchers treated them with each drug, individually and in combination.

The drug combo not only reversed the abnormal gene expression signatures—it also reduced brain degeneration, lowered toxic protein buildup, and restored memory in the mice.

“It’s incredibly encouraging to see the validation of computational predictions in a rigorous animal model,” said Dr. Yadong Huang, senior investigator at Gladstone and co-senior author of the study. “This points toward a real path forward.”

<h2>Why Repurposing Drugs Is a Game-Changer?</h2>

Developing new drugs from scratch is notoriously slow, risky, and expensive. On average, it takes over a decade and billions of dollars to bring a new drug to market. Alzheimer’s drugs, in particular, have a poor track record. Many promising candidates have failed in late-stage trials, often because they target a single mechanism in a disease that’s anything but simple.

Repurposing existing drugs changes that calculus. “These are already FDA-approved,” said Dr. Marina Sirota, co-senior author and interim director of UCSF’s Bakar Computational Health Sciences Institute. “We’re not starting from zero. We know their safety profiles, which speeds up the timeline dramatically.”

Instead of 10 years, researchers believe this approach could move into clinical trials within two or three.

<h2>How Might These Cancer Drugs Work Against Alzheimer’s?</h2>

It’s still early, but there are theories. Letrozole is known to suppress estrogen, a hormone that regulates a wide network of genes, including those involved in cognition and brain metabolism. Estrogen suppression might realign gene expression in neurons affected by Alzheimer’s.

Irinotecan, on the other hand, may dampen inflammation by limiting the proliferation of glial cells. In Alzheimer’s, glia often overreact, causing harmful inflammation that contributes to neurodegeneration.

Other hypotheses suggest these drugs may improve how brain cells use energy—a process that often breaks down in neurodegenerative diseases.

Still, researchers caution that what works in mice doesn’t always translate to humans.

This is where the optimism meets reality. Both <span>letrozole and irinotecan</span> come with known and serious side effects. Letrozole can cause hot flashes, joint pain, and fatigue. Irinotecan’s side effects can include severe diarrhea, nausea, and immune suppression.

“These are potent medications designed to fight cancer,” Dr. Huang noted. “We’ll need to carefully assess whether their risks are acceptable for Alzheimer’s patients, especially in earlier stages of the disease.”

There’s also the question of dosage. Researchers may be able to use lower, safer doses when the drugs are repurposed—something future clinical trials will explore.

So, what’s next? The team is already planning a clinical trial to test the drug combination in people with Alzheimer’s. If successful, this would be the first time a repurposed cancer therapy was proven to meaningfully reverse cognitive decline in humans.

But even if these drugs don’t turn out to be the answer, the methodology could be.

“This is a new way of looking at neurodegenerative disease,” said Dr. Sirota. “Instead of going after one broken part, we’re looking at the whole system—and using big data to identify tools that are already in our toolbox.”

It’s too early to call this a cure. But in a field desperate for fresh approaches, this study offers something rare: real hope.

Alzheimer’s has resisted every easy fix. But by turning to unexpected sources—like cancer drugs—and using advanced data analysis, researchers may have found a new way forward. It’s not a silver bullet, and it won’t be without challenges. But this is one of the most promising leads in years—and it might just mark the beginning of a new chapter in Alzheimer’s treatment.

Health Conditions A-Z

health

alzheimers treatment

cancer drugs alzheimers

letrozole and irinotecan

new alzheimers cure

alzheimers clinical trial

reverse memory loss

repurposed drugs alzheimers

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Alzheimer’s has long been one of medicine’s most frustrating puzzles. Despite decades of research and billions in funding, we still don’t have a cure, and the handful of approved treatments offer only modest relief. But now, scientists from UC San Francisco and the Gladstone Institutes may have uncovered an unlikely lead: two cancer drugs that could potentially reverse Alzheimer’s-related brain changes.The findings, published in the journal Cell, are generating buzz for one big reason: they didn’t come from years of trial-and-error drug development, but from a computational deep dive into big data, gene expression, and real-world patient records. The research team didn’t set out to find a miracle—yet what they discovered might just change the way we treat one of the world’s most devastating neurological diseases.To understand how this started, let’s zoom in on what actually happens in the Alzheimer’s brain.In people with the disease, neurons and glial cells undergo dramatic shifts in gene expression—the biological instructions that tell a cell how to function. These changes disrupt memory, cognition, and eventually basic bodily functions.Instead of targeting a single protein (like beta-amyloid plaques, the long-standing focus in Alzheimer’s research), UCSF scientists took a broader approach. They analyzed single-cell gene expression data from brain tissue donated by individuals with and without Alzheimer’s. This allowed them to pinpoint the exact genetic changes happening in both neurons and glia during disease progression.Then came the twist: they used a database known as the Connectivity Map—essentially a chemical encyclopedia—to match those Alzheimer’s gene expression patterns against thousands of existing drugs. The goal? To find drugs that reverse those patterns.Out of 1,300 drugs studied, 86 had the potential to reverse Alzheimer’s-associated gene changes in at least one brain cell type. Only 25 affected multiple cell types. And of those, just 10 were already FDA-approved.That’s how two unexpected candidates—letrozole (a breast cancer drug) and irinotecan (used for colon and lung cancers)—emerged as frontrunners.The team didn’t stop at computer modeling. They turned to electronic health records, combing through anonymized data from 1.4 million patients over the age of 65 in the UC Health Data Warehouse.What they found was striking: patients treated with letrozole or irinotecan had lower rates of Alzheimer’s. This wasn’t a controlled trial, but it was a strong signal—and one worth testing further.So the team brought the drugs into the lab, using mice genetically engineered to develop Alzheimer’s-like symptoms. As the mice aged and memory declined, the researchers treated them with each drug, individually and in combination.The drug combo not only reversed the abnormal gene expression signatures—it also reduced brain degeneration, lowered toxic protein buildup, and restored memory in the mice.“It’s incredibly encouraging to see the validation of computational predictions in a rigorous animal model,” said Dr. Yadong Huang, senior investigator at Gladstone and co-senior author of the study. “This points toward a real path forward.”Why Repurposing Drugs Is a Game-Changer?Developing new drugs from scratch is notoriously slow, risky, and expensive. On average, it takes over a decade and billions of dollars to bring a new drug to market. Alzheimer’s drugs, in particular, have a poor track record. Many promising candidates have failed in late-stage trials, often because they target a single mechanism in a disease that’s anything but simple.Repurposing existing drugs changes that calculus. “These are already FDA-approved,” said Dr. Marina Sirota, co-senior author and interim director of UCSF’s Bakar Computational Health Sciences Institute. “We’re not starting from zero. We know their safety profiles, which speeds up the timeline dramatically.”Instead of 10 years, researchers believe this approach could move into clinical trials within two or three.How Might These Cancer Drugs Work Against Alzheimer’s?It’s still early, but there are theories. Letrozole is known to suppress estrogen, a hormone that regulates a wide network of genes, including those involved in cognition and brain metabolism. Estrogen suppression might realign gene expression in neurons affected by Alzheimer’s.Irinotecan, on the other hand, may dampen inflammation by limiting the proliferation of glial cells. In Alzheimer’s, glia often overreact, causing harmful inflammation that contributes to neurodegeneration.Other hypotheses suggest these drugs may improve how brain cells use energy—a process that often breaks down in neurodegenerative diseases.Still, researchers caution that what works in mice doesn’t always translate to humans.What About the Side Effects?This is where the optimism meets reality. Both letrozole and irinotecan come with known and serious side effects. Letrozole can cause hot flashes, joint pain, and fatigue. Irinotecan’s side effects can include severe diarrhea, nausea, and immune suppression.“These are potent medications designed to fight cancer,” Dr. Huang noted. “We’ll need to carefully assess whether their risks are acceptable for Alzheimer’s patients, especially in earlier stages of the disease.”There’s also the question of dosage. Researchers may be able to use lower, safer doses when the drugs are repurposed—something future clinical trials will explore.So, what’s next? The team is already planning a clinical trial to test the drug combination in people with Alzheimer’s. If successful, this would be the first time a repurposed cancer therapy was proven to meaningfully reverse cognitive decline in humans.But even if these drugs don’t turn out to be the answer, the methodology could be.“This is a new way of looking at neurodegenerative disease,” said Dr. Sirota. “Instead of going after one broken part, we’re looking at the whole system—and using big data to identify tools that are already in our toolbox.”It’s too early to call this a cure. But in a field desperate for fresh approaches, this study offers something rare: real hope.Alzheimer’s has resisted every easy fix. But by turning to unexpected sources—like cancer drugs—and using advanced data analysis, researchers may have found a new way forward. It’s not a silver bullet, and it won’t be without challenges. But this is one of the most promising leads in years—and it might just mark the beginning of a new chapter in Alzheimer’s treatment.

could these common cancer drugs could be the key to reversing and treating alzheimer’s?

Ishita Roy

FDA Clears Prefilled Syringe for Shingles Vaccine, Aim Is for Smoother Administration

RSV Vaccine For Expecting Moms Cuts Risk Of Severe Lung Infections In Infants by 72%; Premature Babies To Be Vaccinated Before Winter

rsv vaccine for expecting moms cuts risk of severe lung infections in infants by 72%; premature babies to be vaccinated before winter

Pfizer COVID-19 Vaccine Linked To Major Eye Dysfunction, Study Finds

pfizer covid-19 shot linked to major eye dysfunction, study finds

'Obsolete And Unnecessary': FDA Set To Revoke 52 Nutrition And Labeling Rules

"obsolete and unnecessary": fda set to revoke 52 nutrition and labeling rules

Hepatitis A Cases Surge In Pune Amid Monsoon Rains, Contaminated Water Suspected; How To Stay Safe?

hepatitis a cases surge in pune amid monsoon rains, contaminated water suspected; how to stay safe?

In a move that could make the <span>shingles</span> vaccination process smoother for both patients and healthcare providers, the U.S. Food and Drug Administration (FDA) has approved a new prefilled syringe version of Shingrix—the widely used vaccine for shingles, or herpes zoster.

The vaccine, developed by global biopharma company GSK, has already been a go-to option for adults aged 50 and older and certain immunocompromised individuals. With this newly approved version, the process of getting vaccinated becomes significantly simpler, without compromising efficacy or safety.

<h4>From Two Vials to One Prefilled Syringe</h4>

Until now, Shingrix has been administered in a two-step process. It involved combining two separate vials—a freeze-dried (lyophilized) powder containing the antigen, and a liquid adjuvant, by trained healthcare workers just before the vaccine was given. 

This mixing step, while manageable, added a layer of complexity that could sometimes slow down the vaccination process, particularly in busy clinics or pharmacies.

With the FDA’s approval of the prefilled syringe, that extra step is eliminated. The vaccine is now available in a ready-to-use format, making the administration process quicker and reducing the chances of handling errors. 

For healthcare professionals, this means less prep time and more streamlined delivery. For patients, it could mean shorter waiting times and potentially increased access.

<h4>Who Can Get the New Shingrix Syringe?</h4>

The approved prefilled syringe format maintains the same usage guidelines as the original formulation. It is licensed for use in:

<ul><li>Adults aged 50 years and older</li><li>Adults aged 18 years and older who are or will be at increased risk of shingles due to immunodeficiency or immunosuppressive conditions (from either illness or medical treatments)</li></ul>

This broadened scope ensures that vulnerable individuals, like those undergoing chemotherapy, transplant patients, or people living with HIV, can continue receiving this critical protection against shingles, now in a more efficient form.

Shingles isn’t rare—in fact, according to the Centers for Disease Control and Prevention (CDC), about 1 in 3 Americans will develop shingles in their lifetime. 

It is caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox. When it comes back, often years later, it manifests as a painful rash, often accompanied by burning or shooting pain. 

In some cases, it can lead to long-term complications like postherpetic neuralgia, where pain lingers for months or even years after the rash clears.

“This new presentation of Shingrix was developed to streamline the vaccination process, supporting health care professionals to provide protection against shingles,” said Tony Wood, Chief Scientific Officer at GSK, in a statement. “Shingles is a disease that one in three U.S. adults will develop in their lifetime.”

The FDA’s decision was based on data that demonstrated technical comparability between the new prefilled syringe format and the original two-vial version. That means the vaccine’s safety, quality, and effectiveness remain unchanged in the updated version.

shingles

health news

health news US

USA health news

shingles vaccine

In a move that could make the shingles vaccination process smoother for both patients and healthcare providers, the U.S. Food and Drug Administration (FDA) has approved a new prefilled syringe version of Shingrix—the widely used vaccine for shingles, or herpes zoster.The vaccine, developed by global biopharma company GSK, has already been a go-to option for adults aged 50 and older and certain immunocompromised individuals. With this newly approved version, the process of getting vaccinated becomes significantly simpler, without compromising efficacy or safety.From Two Vials to One Prefilled SyringeUntil now, Shingrix has been administered in a two-step process. It involved combining two separate vials—a freeze-dried (lyophilized) powder containing the antigen, and a liquid adjuvant, by trained healthcare workers just before the vaccine was given. This mixing step, while manageable, added a layer of complexity that could sometimes slow down the vaccination process, particularly in busy clinics or pharmacies.With the FDA’s approval of the prefilled syringe, that extra step is eliminated. The vaccine is now available in a ready-to-use format, making the administration process quicker and reducing the chances of handling errors. For healthcare professionals, this means less prep time and more streamlined delivery. For patients, it could mean shorter waiting times and potentially increased access.Who Can Get the New Shingrix Syringe?The approved prefilled syringe format maintains the same usage guidelines as the original formulation. It is licensed for use in:Adults aged 50 years and olderAdults aged 18 years and older who are or will be at increased risk of shingles due to immunodeficiency or immunosuppressive conditions (from either illness or medical treatments)This broadened scope ensures that vulnerable individuals, like those undergoing chemotherapy, transplant patients, or people living with HIV, can continue receiving this critical protection against shingles, now in a more efficient form.Why This MattersShingles isn’t rare—in fact, according to the Centers for Disease Control and Prevention (CDC), about 1 in 3 Americans will develop shingles in their lifetime. It is caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox. When it comes back, often years later, it manifests as a painful rash, often accompanied by burning or shooting pain. In some cases, it can lead to long-term complications like postherpetic neuralgia, where pain lingers for months or even years after the rash clears.“This new presentation of Shingrix was developed to streamline the vaccination process, supporting health care professionals to provide protection against shingles,” said Tony Wood, Chief Scientific Officer at GSK, in a statement. “Shingles is a disease that one in three U.S. adults will develop in their lifetime.”The FDA’s decision was based on data that demonstrated technical comparability between the new prefilled syringe format and the original two-vial version. That means the vaccine’s safety, quality, and effectiveness remain unchanged in the updated version.

fda clears prefilled syringe for shingles vaccine, aim is for smoother administration

Bruce Willis Health Update: A Diagnostic Timeline From Aphasia To Dementia

World Brain Day 2025: History, Theme, And Significance

world brain day 2025: history, theme, and significance

Health & Wellness

Dementia Caregivers Often End Up Being Nieces And Nephews Of The Family

dementia caregivers often end up being nieces and nephews of the family

12-Year-Old Teen Dies From Rare Brain Tumor After Unusual Early Signs, Grieving Mother Urges Parents To Watch For Subtle Symptoms

12-year-old teen dies from rare brain tumor after unusual early signs, grieving mother urges parents to watch for subtle symptoms

Not Dementia, Not Bipolar: The Hidden Brain Condition Behind Misleading Symptoms

not dementia, not bipolar: the hidden brain condition behind misleading symptoms

The beloved <em>Die Hard</em> star, <span>Bruce Willis</span>, now 70, is spending his retirement surrounded by close family while navigating the challenges of <span>frontotemporal dementia</span> (FTD), a progressive brain disorder. Willis publicly stepped away from acting in 2022 after being diagnosed with <span>aphasia</span>, a condition that affects the ability to communicate. A year later, his family revealed the underlying cause: FTD, a condition that gradually affects speech, behavior, and cognition.

Today, Willis remains alive and cared for at home, surrounded by his blended family, including wife Emma Heming Willis, ex-wife Demi Moore, and his five daughters. While his public presence has faded, his family's updates keep fans connected to his journey.

<h4>From Aphasia to Frontotemporal <span rel="noindex">Dementia</span></h4>

In March 2022, fans were shocked by a family statement revealing Willis had been diagnosed with aphasia. The announcement was brief but clear: the condition was affecting his cognitive abilities and making it impossible for him to continue his acting career. However, aphasia was just one piece of the puzzle.

By February 2023, a more specific diagnosis emerged. The Willis family confirmed Bruce was dealing with frontotemporal dementia, a degenerative condition that often begins with language difficulties and eventually affects decision-making, emotional regulation, and behavior.

"Challenges with communication are just one symptom of the disease Bruce faces," the family shared at the time, emphasizing that the condition affects far more than speech.

Unlike Alzheimer’s disease, FTD tends to strike earlier, often in one’s 50s or 60s—and can progress quickly. It affects the frontal and temporal lobes of the brain, areas associated with language, behavior, and executive function. Currently, there is no cure.

<h4>The Emotional Weight of Caregiving</h4>

Emma Heming Willis has taken on a leading role in Bruce's care and advocacy. Over the past two years, she’s become a vocal supporter for caregivers and families dealing with dementia.

In a <em>People </em>magazine interview published in May 2025, Emma opened up about the early days of Bruce’s diagnosis. “We received a diagnosis and were sent away with no hope, no guidance, no nothing. I really had to figure out how to put resources into place,” she shared, reflecting the emotional and logistical maze caregivers often face.

Her journey inspired her to create resources and support networks for others in similar situations. She continues to document parts of this experience on social media—not to focus on Bruce’s decline, but to highlight the love, humor, and resilience that continue to exist in their home.

Demi Moore and Bruce’s daughters, Rumer, Scout, Tallulah, Mabel, and Evelyn—have all rallied around him. Their Instagram tributes are filled with gentle moments: shared hugs, quiet celebrations, and messages of gratitude for their father.

For Bruce’s 70th birthday earlier this year, Demi posted a photo with the caption, “Quality time with our BW,” offering a glimpse into their enduring bond. Similar updates on Father’s Day and family anniversaries have become testaments to togetherness in the face of change.

Rather than leaning into clinical details, the family’s posts focus on presence and love—showing the world how meaningful care can look even during decline.

His final films, including <em>Assassin </em>and <em>Detective Knight: Independence </em>(both released in 2023), were completed amid his health challenges. Retrospectively, fans and critics noted that the simpler roles and shorter production schedules may have been early accommodations to his changing condition.

When his retirement was officially announced on March 30, 2022, daughter Rumer posted:

“To Bruce’s amazing supporters… Bruce has been experiencing some health issues and has recently been diagnosed with aphasia… With much consideration, Bruce is stepping away from the career that has meant so much to him.”

<h4>From Celebrity Story to Public Health Conversation</h4>

Bruce Willis’ diagnosis has helped bring attention to aphasia and FTD, two conditions that are often misunderstood and under-discussed. His family's openness has inspired conversations around the emotional and practical realities of caregiving, early diagnosis, and the importance of support.

bruce willis

brain health

australia health news

health news australia

dementia

aphasia

frontotemporal dementia

The beloved Die Hard star, Bruce Willis, now 70, is spending his retirement surrounded by close family while navigating the challenges of frontotemporal dementia (FTD), a progressive brain disorder. Willis publicly stepped away from acting in 2022 after being diagnosed with aphasia, a condition that affects the ability to communicate. A year later, his family revealed the underlying cause: FTD, a condition that gradually affects speech, behavior, and cognition.Today, Willis remains alive and cared for at home, surrounded by his blended family, including wife Emma Heming Willis, ex-wife Demi Moore, and his five daughters. While his public presence has faded, his family's updates keep fans connected to his journey.From Aphasia to Frontotemporal DementiaIn March 2022, fans were shocked by a family statement revealing Willis had been diagnosed with aphasia. The announcement was brief but clear: the condition was affecting his cognitive abilities and making it impossible for him to continue his acting career. However, aphasia was just one piece of the puzzle.By February 2023, a more specific diagnosis emerged. The Willis family confirmed Bruce was dealing with frontotemporal dementia, a degenerative condition that often begins with language difficulties and eventually affects decision-making, emotional regulation, and behavior."Challenges with communication are just one symptom of the disease Bruce faces," the family shared at the time, emphasizing that the condition affects far more than speech.Unlike Alzheimer’s disease, FTD tends to strike earlier, often in one’s 50s or 60s—and can progress quickly. It affects the frontal and temporal lobes of the brain, areas associated with language, behavior, and executive function. Currently, there is no cure.The Emotional Weight of CaregivingEmma Heming Willis has taken on a leading role in Bruce's care and advocacy. Over the past two years, she’s become a vocal supporter for caregivers and families dealing with dementia.In a People magazine interview published in May 2025, Emma opened up about the early days of Bruce’s diagnosis. “We received a diagnosis and were sent away with no hope, no guidance, no nothing. I really had to figure out how to put resources into place,” she shared, reflecting the emotional and logistical maze caregivers often face.Her journey inspired her to create resources and support networks for others in similar situations. She continues to document parts of this experience on social media—not to focus on Bruce’s decline, but to highlight the love, humor, and resilience that continue to exist in their home.A Strong Network of CaregiversDemi Moore and Bruce’s daughters, Rumer, Scout, Tallulah, Mabel, and Evelyn—have all rallied around him. Their Instagram tributes are filled with gentle moments: shared hugs, quiet celebrations, and messages of gratitude for their father.For Bruce’s 70th birthday earlier this year, Demi posted a photo with the caption, “Quality time with our BW,” offering a glimpse into their enduring bond. Similar updates on Father’s Day and family anniversaries have become testaments to togetherness in the face of change.Rather than leaning into clinical details, the family’s posts focus on presence and love—showing the world how meaningful care can look even during decline.His final films, including Assassin and Detective Knight: Independence (both released in 2023), were completed amid his health challenges. Retrospectively, fans and critics noted that the simpler roles and shorter production schedules may have been early accommodations to his changing condition.When his retirement was officially announced on March 30, 2022, daughter Rumer posted:“To Bruce’s amazing supporters… Bruce has been experiencing some health issues and has recently been diagnosed with aphasia… With much consideration, Bruce is stepping away from the career that has meant so much to him.”From Celebrity Story to Public Health ConversationBruce Willis’ diagnosis has helped bring attention to aphasia and FTD, two conditions that are often misunderstood and under-discussed. His family's openness has inspired conversations around the emotional and practical realities of caregiving, early diagnosis, and the importance of support.

bruce willis health update: a diagnostic timeline from aphasia to dementia

World Brain Day 2025: Signs of Brain Tumors You Might Be Dismissing as “Just Stress”

signs of brain tumors you might be dismissing as “just stress”

World Brain Day 2025: Could Your Brain Heal Itself? Why Scientists Are Betting On Neuroplasticity To Treat Neurological Disorders

world brain day 2025: could your brain heal itself? why scientists are betting on neuroplasticity to treat neurological disorders

Every year on July 22, <span>World Brain Day</span> is observed across the globe to raise awareness about the importance of <span>brain health</span>. This day also aims at encouraging better knowledge on neurological care, early invention, and in educating people about the same. 

<h2>History of World <span rel="noindex">Brain Day</span></h2>

It was on 2014, when the World Federation of Neurology (WFN) started the event of World Brain Day, in order to <a href="https://www.healthandme.com/health-wellness/world-brain-day-2025-could-your-brain-heal-itself-why-scientists-are-betting-on-neuroplasticity-to-treat-neurological-disorders-article-152320891" data-type="tilCustomLink" target="_blank">safeguard neurological health</a> from earliest phases of development, right from childhood, adulthood, and older age. 

Neurological disorders are one of the leading causes of disability-adjusted life years and the second leading cause of mortality, globally. 

<h2><span rel="noindex">World Brain Day 2025</span> Theme: "Brain Health for All Ages" - What It Means for You</h2>

This year's theme for World Brain Day is, 'Brain Health For All Ages'. This theme aims to prioritise brain health and also echoes the concept that neurological health must be safeguarded at all ages. Whether you are a child, caring for one, a parent, or an elderly. 

World Brain Day shines a spotlight on the growing global challenge posed by neurological disorders. From stroke and dementia to epilepsy and Parkinson’s disease, these conditions not only affect the daily lives of millions but also place a heavy burden on healthcare systems around the world.

This annual health campaign plays a vital role by:

<ul><li>Raising public awareness about brain health and neurological conditions, with a focus on early detection and timely treatment.</li><li>Highlighting the need for ongoing research to improve treatment options, discover potential cures, and enhance prevention strategies.</li><li>Creating a sense of solidarity among patients, caregivers, and healthcare professionals, fostering support and shared purpose.</li><li>Urging policymakers to make brain health a priority in public health planning through better policies and increased funding.</li></ul>

<strong>Early life matters:</strong> Brain health starts in the womb. Maternal health and early childhood experiences have a lasting impact on brain development and future neurological outcomes.

<strong>Adulthood is crucial:</strong> The lifestyle choices we make—such as exercise, diet, sleep, and stress management—play a major role in determining our risk of neurological disorders later in life.

<strong>Ageing doesn’t mean decline: </strong>While certain changes in brain function are natural with age, proactive steps—like staying mentally and socially engaged—can preserve cognitive health and improve quality of life.

By adopting a lifespan perspective, this year’s campaign encourages everyone to take brain health seriously, no matter their age. Because a healthy brain means a better life—for individuals, families, and society as a whole.

<h2>7 Early Signs That Must Not Be Ignored To Promote A Healthy Brain</h2>

Spotting the early signs of a brain tumor can make a crucial difference in diagnosis and treatment. While symptoms can vary depending on the tumor’s type and location—like Pituitary Adenoma, Meningioma, or Metastatic Brain Tumors—there are several common warning signs that deserve attention.

<h3>Persistent Headaches That Get Worse Over Time</h3>

Not all headaches are a red flag, but if yours are becoming more frequent, especially worse in the mornings or during physical activity, it could indicate increased pressure in the brain. Any noticeable change in headache pattern, intensity, or timing should be discussed with a doctor.

Blurred vision, loss of side (peripheral) vision, or sudden issues with sight could signal pressure on the optic nerves. Tumors located near the visual pathways, such as Pituitary Adenomas, often show up through these kinds of symptoms.

If you’ve never had a seizure before and suddenly experience one, it’s a serious sign that should never be ignored. Seizures can occur when a tumor disrupts the brain’s normal electrical activity.

<h3>Balance Problems or Coordination Issues</h3>

Feeling unusually unsteady, dizzy, or having difficulty walking could point to a tumor in the cerebellum or brainstem—areas responsible for balance and coordination. If you're suddenly clumsy or off-balance, it’s time to get checked.

<h3>Changes in Memory, Mood, or Personality</h3>

A brain tumor in the frontal or temporal lobes may affect how a person thinks, feels, or behaves. Sudden mood swings, memory lapses, confusion, or personality changes—especially if noticeable to others—are warning signs not to be brushed off as stress.

Unexplained weakness, tingling, or numbness—especially on one side of the body—might signal a tumor pressing on parts of the brain that control movement and sensation.

<h3>Ongoing Nausea or Vomiting Without a Clear Cause</h3>

If you're frequently nauseous or vomiting and it’s not related to food poisoning, pregnancy, or a stomach bug, it could be due to increased pressure inside the skull caused by a tumor.

world brain day

world brain day 2025

brain day

brain day 2025

Every year on July 22, World Brain Day is observed across the globe to raise awareness about the importance of brain health. This day also aims at encouraging better knowledge on neurological care, early invention, and in educating people about the same. History of World Brain DayIt was on 2014, when the World Federation of Neurology (WFN) started the event of World Brain Day, in order to safeguard neurological health from earliest phases of development, right from childhood, adulthood, and older age. Neurological disorders are one of the leading causes of disability-adjusted life years and the second leading cause of mortality, globally. World Brain Day 2025 Theme: "Brain Health for All Ages" - What It Means for YouThis year's theme for World Brain Day is, 'Brain Health For All Ages'. This theme aims to prioritise brain health and also echoes the concept that neurological health must be safeguarded at all ages. Whether you are a child, caring for one, a parent, or an elderly. Significance of World Brain DayWorld Brain Day shines a spotlight on the growing global challenge posed by neurological disorders. From stroke and dementia to epilepsy and Parkinson’s disease, these conditions not only affect the daily lives of millions but also place a heavy burden on healthcare systems around the world.This annual health campaign plays a vital role by:Raising public awareness about brain health and neurological conditions, with a focus on early detection and timely treatment.Highlighting the need for ongoing research to improve treatment options, discover potential cures, and enhance prevention strategies.Creating a sense of solidarity among patients, caregivers, and healthcare professionals, fostering support and shared purpose.Urging policymakers to make brain health a priority in public health planning through better policies and increased funding.Importance of World Brain DayEarly life matters: Brain health starts in the womb. Maternal health and early childhood experiences have a lasting impact on brain development and future neurological outcomes.Adulthood is crucial: The lifestyle choices we make—such as exercise, diet, sleep, and stress management—play a major role in determining our risk of neurological disorders later in life.Ageing doesn’t mean decline: While certain changes in brain function are natural with age, proactive steps—like staying mentally and socially engaged—can preserve cognitive health and improve quality of life.By adopting a lifespan perspective, this year’s campaign encourages everyone to take brain health seriously, no matter their age. Because a healthy brain means a better life—for individuals, families, and society as a whole.7 Early Signs That Must Not Be Ignored To Promote A Healthy BrainSpotting the early signs of a brain tumor can make a crucial difference in diagnosis and treatment. While symptoms can vary depending on the tumor’s type and location—like Pituitary Adenoma, Meningioma, or Metastatic Brain Tumors—there are several common warning signs that deserve attention.Persistent Headaches That Get Worse Over TimeNot all headaches are a red flag, but if yours are becoming more frequent, especially worse in the mornings or during physical activity, it could indicate increased pressure in the brain. Any noticeable change in headache pattern, intensity, or timing should be discussed with a doctor.Vision Changes or Double VisionBlurred vision, loss of side (peripheral) vision, or sudden issues with sight could signal pressure on the optic nerves. Tumors located near the visual pathways, such as Pituitary Adenomas, often show up through these kinds of symptoms.New-Onset SeizuresIf you’ve never had a seizure before and suddenly experience one, it’s a serious sign that should never be ignored. Seizures can occur when a tumor disrupts the brain’s normal electrical activity.Balance Problems or Coordination IssuesFeeling unusually unsteady, dizzy, or having difficulty walking could point to a tumor in the cerebellum or brainstem—areas responsible for balance and coordination. If you're suddenly clumsy or off-balance, it’s time to get checked.Changes in Memory, Mood, or PersonalityA brain tumor in the frontal or temporal lobes may affect how a person thinks, feels, or behaves. Sudden mood swings, memory lapses, confusion, or personality changes—especially if noticeable to others—are warning signs not to be brushed off as stress.Numbness or Weakness in LimbsUnexplained weakness, tingling, or numbness—especially on one side of the body—might signal a tumor pressing on parts of the brain that control movement and sensation.Ongoing Nausea or Vomiting Without a Clear CauseIf you're frequently nauseous or vomiting and it’s not related to food poisoning, pregnancy, or a stomach bug, it could be due to increased pressure inside the skull caused by a tumor.

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