Health and Me

Tanya Dutt

What Are The New COVID-19 Variants Spreading In May 2025?

What New COVID-19 Variants Spreading In May 2025?

The most recent entrant to the WHO’s list is NB.1.8.1, derived from recombinant ancestor XDV.1.5.1. With multiple mutations in its spike protein, NB.1.8.1 is being closely observed for its potential to escape immune responses.

More than five years since <span>COVID-19</span> was declared a pandemic, the virus is far from gone. While global headlines may no longer be dominated by daily case counts, SARS-CoV-2—the virus responsible for COVID-19—continues to evolve, adapt, and spread in communities worldwide. In May 2025, a new wave of variants is quietly shaping the trajectory of the virus and prompting renewed concern among scientists and health professionals.

Viruses are, by nature, constantly mutating. As SARS-CoV-2 moves from person to person, random genetic changes—known as mutations—accumulate. Most mutations are harmless, but some enhance the virus’s ability to spread, evade immunity, or cause severe illness.

When a group of mutations significantly alters the virus's behavior, it is classified as a variant. These variants are then grouped by the World Health Organization (WHO) and CDC into three broad categories:

<ul><li>Variants Under Monitoring (VUM)</li><li>Variants of Interest (VOI)</li><li>Variants of Concern (VOC)</li></ul>

This classification is vital for public health responses, vaccine development, and treatment planning.

<h2>Current Variants Circulating in May 2025</h2>

According to global health monitoring systems, the major COVID-19 variants circulating in May 2025 include:

Notably, all of these are descendants of Omicron, specifically from the lineage KP.1.1.3, itself a subvariant of JN.1—the dominant variant during the winter surge of 2023–2024.

<table class="redcator-table-advance"><tbody><tr><td><strong>COVID-19 VARIANT</strong></td><td><strong>FEATURE</strong></td><td><strong>SYMPTOMS</strong></td></tr><tr><td>KP.3</td><td>KP.3 belongs to a cluster of Omicron descendants collectively referred to as FLiRT variants. This group also includes KP.2 (the prior dominant variant in the U.S.) and KP.1.1. Though KP.3 hasn’t demonstrated drastically different clinical outcomes, it continues to be the most prevalent variant across the U.S. and parts of Europe.</td><td>Fever or chills, Cough, Shortness of breath, Fatigue, Loss of taste or smell, Sore throat, Diarrhea and nausea</td></tr><tr><td>KP.3.1.1</td><td>A sublineage of KP.3, KP.3.1.1 is emerging as a significant global variant. It is now the most common variant among the JN.1-derived strains, contributing to sustained hospital visits and positive test rates, especially in at-risk age groups.</td><td>Although not more severe in symptoms, its high transmissibility raises concerns for immunocompromised individuals and communities with low vaccination rates.</td></tr><tr><td>LB.1</td><td>Ranked third among the current U.S. variants, LB.1 has caught attention for anecdotal reports of particularly severe sore throats. It is, again, part of the FLiRT family and a direct descendant of JN.1.</td><td>Intense sore throat, Fatigue, nasal congestion, Fever</td></tr><tr><td>XEC</td><td>XEC is different from its peers—it's a recombinant variant, meaning it emerged from the blending of two separate Omicron strains, KS.1.1 and KP.3.3, within a single infected individual.</td><td>High fever, Muscle aches, Sore throat, Dry cough, Extreme tiredness</td></tr><tr><td>LP.8.1</td><td>First identified in July 2024 and now labeled a Variant Under Monitoring by the WHO, LP.8.1 has demonstrated significant growth in multiple countries. </td><td>Continuous cough, Loss of taste or smell, Shortness of breath, Muscle aches, Gastrointestinal discomfort</td></tr><tr><td>NB.1.8.1</td><td>The most recent entrant to the WHO’s list is NB.1.8.1, derived from recombinant ancestor XDV.1.5.1. With multiple mutations in its spike protein, NB.1.8.1 is being closely observed for its potential to escape immune responses.</td><td>Fever, Dry cough, Sore throat, Headache, Mild gastrointestinal issues</td></tr></tbody><tbody></tbody><tbody></tbody><tbody></tbody></table><h2>Can COVID-19 Tests Identify the Variant?</h2>

Most standard COVID-19 tests (PCR or antigen) only detect whether the virus is present—not which variant you’ve contracted. For that, scientists rely on genomic sequencing, which is typically used for public health tracking rather than individual diagnosis.

So if you test positive, assume you may have one of the circulating variants and act accordingly.

While some variants can partially evade immunity, vaccination remains one of the most effective ways to reduce severe illness, hospitalization, and death.

Current recommendations from public health agencies include:

<ul><li>Getting the updated bivalent or variant-specific booster</li><li>Wearing masks in crowded indoor settings</li><li>Avoiding high-risk environments, especially if you're immunocompromised</li><li>Practicing good hand hygiene</li><li>Isolating if you feel sick</li></ul>

As one infectious disease expert put it, “We still have a lot of virus in circulation—masks, vaccines, and vigilance continue to be our best tools.”

In May 2025, the COVID-19 landscape continues to shift. While symptoms largely mirror earlier waves, the evolving nature of variants like KP.3.1.1, LB.1, and NB.1.8.1 highlights the importance of surveillance, booster uptake, and public awareness.

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The most recent entrant to the WHO’s list is NB.1.8.1, derived from recombinant ancestor XDV.1.5.1. With multiple mutations in its spike protein, NB.1.8.1 is being closely observed for its potential to escape immune responses.More than five years since COVID-19 was declared a pandemic, the virus is far from gone. While global headlines may no longer be dominated by daily case counts, SARS-CoV-2—the virus responsible for COVID-19—continues to evolve, adapt, and spread in communities worldwide. In May 2025, a new wave of variants is quietly shaping the trajectory of the virus and prompting renewed concern among scientists and health professionals.Viruses are, by nature, constantly mutating. As SARS-CoV-2 moves from person to person, random genetic changes—known as mutations—accumulate. Most mutations are harmless, but some enhance the virus’s ability to spread, evade immunity, or cause severe illness.When a group of mutations significantly alters the virus's behavior, it is classified as a variant. These variants are then grouped by the World Health Organization (WHO) and CDC into three broad categories:Variants Under Monitoring (VUM)Variants of Interest (VOI)Variants of Concern (VOC)This classification is vital for public health responses, vaccine development, and treatment planning.Current Variants Circulating in May 2025According to global health monitoring systems, the major COVID-19 variants circulating in May 2025 include:KP.3KP.3.1.1LB.1XECLP.8.1NB.1.8.1Notably, all of these are descendants of Omicron, specifically from the lineage KP.1.1.3, itself a subvariant of JN.1—the dominant variant during the winter surge of 2023–2024.COVID-19 VARIANTFEATURESYMPTOMSKP.3KP.3 belongs to a cluster of Omicron descendants collectively referred to as FLiRT variants. This group also includes KP.2 (the prior dominant variant in the U.S.) and KP.1.1. Though KP.3 hasn’t demonstrated drastically different clinical outcomes, it continues to be the most prevalent variant across the U.S. and parts of Europe.Fever or chills, Cough, Shortness of breath, Fatigue, Loss of taste or smell, Sore throat, Diarrhea and nauseaKP.3.1.1A sublineage of KP.3, KP.3.1.1 is emerging as a significant global variant. It is now the most common variant among the JN.1-derived strains, contributing to sustained hospital visits and positive test rates, especially in at-risk age groups.Although not more severe in symptoms, its high transmissibility raises concerns for immunocompromised individuals and communities with low vaccination rates.LB.1Ranked third among the current U.S. variants, LB.1 has caught attention for anecdotal reports of particularly severe sore throats. It is, again, part of the FLiRT family and a direct descendant of JN.1.Intense sore throat, Fatigue, nasal congestion, FeverXECXEC is different from its peers—it's a recombinant variant, meaning it emerged from the blending of two separate Omicron strains, KS.1.1 and KP.3.3, within a single infected individual.High fever, Muscle aches, Sore throat, Dry cough, Extreme tirednessLP.8.1First identified in July 2024 and now labeled a Variant Under Monitoring by the WHO, LP.8.1 has demonstrated significant growth in multiple countries. Continuous cough, Loss of taste or smell, Shortness of breath, Muscle aches, Gastrointestinal discomfortNB.1.8.1The most recent entrant to the WHO’s list is NB.1.8.1, derived from recombinant ancestor XDV.1.5.1. With multiple mutations in its spike protein, NB.1.8.1 is being closely observed for its potential to escape immune responses.Fever, Dry cough, Sore throat, Headache, Mild gastrointestinal issuesCan COVID-19 Tests Identify the Variant?Most standard COVID-19 tests (PCR or antigen) only detect whether the virus is present—not which variant you’ve contracted. For that, scientists rely on genomic sequencing, which is typically used for public health tracking rather than individual diagnosis.So if you test positive, assume you may have one of the circulating variants and act accordingly.Do the Current Vaccines Work?While some variants can partially evade immunity, vaccination remains one of the most effective ways to reduce severe illness, hospitalization, and death.Current recommendations from public health agencies include:Getting the updated bivalent or variant-specific boosterWearing masks in crowded indoor settingsAvoiding high-risk environments, especially if you're immunocompromisedPracticing good hand hygieneIsolating if you feel sickAs one infectious disease expert put it, “We still have a lot of virus in circulation—masks, vaccines, and vigilance continue to be our best tools.”In May 2025, the COVID-19 landscape continues to shift. While symptoms largely mirror earlier waves, the evolving nature of variants like KP.3.1.1, LB.1, and NB.1.8.1 highlights the importance of surveillance, booster uptake, and public awareness.

what new covid-19 variants spreading in may 2025?

Ishita Roy

amid measles outbreak, Texas makes vaccine exemption easier for kids

New COVID Variant NB.1.8.1 Spreads in US: Symptoms, Risk Factors And Who Can Get The Booster?

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Texas is experiencing the nation’s worst <span>measles</span> outbreak in over 20 years. More than 700 people have been infected so far, with dozens hospitalized and two unvaccinated children dying due to complications. This surge in a disease once declared eliminated in the U.S. has raised alarms among public health experts and lawmakers alike.

The outbreak began earlier this year in West Texas’ Mennonite communities, where vaccine hesitancy is common. It soon spread to other areas with low immunization rates, highlighting the vulnerability of unvaccinated populations. Despite existing vaccine requirements for schoolchildren in Texas, exemptions for religious, personal, or medical reasons remain legal and increasingly popular.

Even as the measles outbreak shows signs of slowing, Texas lawmakers have passed a bill that would make it significantly easier for parents to exempt their children from vaccinations required for school enrollment—vaccines that protect against diseases like measles, whooping cough, polio, and hepatitis A and B.

Under current law, parents must request exemption forms from the state health department by mail, a process that can take weeks. The new bill, now awaiting Republican Governor Greg Abbott’s signature, allows families to download the forms online, though they must still be notarized before being submitted to schools.

Supporters argue that the bill merely streamlines a process that is already legal. “This bill is not about whether vaccines are good or bad,” said Jackie Schlegel, founder of Texans for Medical Freedom. “It's about government efficiency and keeping kids in schools.”

Public health experts are sounding the alarm. Rekha Lakshmanan, chief strategy officer for the Immunization Partnership, warned lawmakers that simplifying exemption access could have deadly consequences. “If this bill becomes law, Texas is likely to see more illness, more death and higher health care costs for families and businesses,” she testified.

She also pointed to the outbreak itself as a warning. “It is the canary in the coal mine screaming at the top of its lungs.”

Texas’ <span>vaccine exemption</span> rates have surged in recent years. The Department of State Health Services received nearly 153,000 exemption requests for the 2023-24 school year, almost double the number from five years ago.

Texas is not alone. Across the country, conservative lawmakers have introduced hundreds of vaccine-related bills in 2025, many of which weaken vaccine mandates. Brent Ewig of the Association of Immunization Managers said the group is tracking nearly 600 such bills this year, the majority of which are not pro-vaccine.

This shift follows growing anti-vaccine sentiment sparked by the COVID-19 pandemic and amplified by figures like Robert F. Kennedy Jr., who was recently appointed U.S. Secretary of Health and Human Services.

<h4>Future Legal Challenges and Proposals</h4>

Another bill pending in the Texas Senate could allow lawsuits against vaccine makers if their products cause harm, provided they advertise in Texas. This bill has faced strong opposition from business groups, including the Texas Association of Manufacturers.

The proposal is led by Rep. Shelley Luther, known for defying COVID restrictions in 2020. Her push represents a broader movement questioning vaccine safety and government mandates.

As Texas continues to recover from its ongoing outbreak, critics fear that easing exemption rules may put even more children and communities at risk.

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Texas is experiencing the nation’s worst measles outbreak in over 20 years. More than 700 people have been infected so far, with dozens hospitalized and two unvaccinated children dying due to complications. This surge in a disease once declared eliminated in the U.S. has raised alarms among public health experts and lawmakers alike.The outbreak began earlier this year in West Texas’ Mennonite communities, where vaccine hesitancy is common. It soon spread to other areas with low immunization rates, highlighting the vulnerability of unvaccinated populations. Despite existing vaccine requirements for schoolchildren in Texas, exemptions for religious, personal, or medical reasons remain legal and increasingly popular.Controversial New LegislationEven as the measles outbreak shows signs of slowing, Texas lawmakers have passed a bill that would make it significantly easier for parents to exempt their children from vaccinations required for school enrollment—vaccines that protect against diseases like measles, whooping cough, polio, and hepatitis A and B.Under current law, parents must request exemption forms from the state health department by mail, a process that can take weeks. The new bill, now awaiting Republican Governor Greg Abbott’s signature, allows families to download the forms online, though they must still be notarized before being submitted to schools.Supporters argue that the bill merely streamlines a process that is already legal. “This bill is not about whether vaccines are good or bad,” said Jackie Schlegel, founder of Texans for Medical Freedom. “It's about government efficiency and keeping kids in schools.”Health Officials Push BackPublic health experts are sounding the alarm. Rekha Lakshmanan, chief strategy officer for the Immunization Partnership, warned lawmakers that simplifying exemption access could have deadly consequences. “If this bill becomes law, Texas is likely to see more illness, more death and higher health care costs for families and businesses,” she testified.She also pointed to the outbreak itself as a warning. “It is the canary in the coal mine screaming at the top of its lungs.”Texas’ vaccine exemption rates have surged in recent years. The Department of State Health Services received nearly 153,000 exemption requests for the 2023-24 school year, almost double the number from five years ago.A Broader TrendTexas is not alone. Across the country, conservative lawmakers have introduced hundreds of vaccine-related bills in 2025, many of which weaken vaccine mandates. Brent Ewig of the Association of Immunization Managers said the group is tracking nearly 600 such bills this year, the majority of which are not pro-vaccine.This shift follows growing anti-vaccine sentiment sparked by the COVID-19 pandemic and amplified by figures like Robert F. Kennedy Jr., who was recently appointed U.S. Secretary of Health and Human Services.Future Legal Challenges and ProposalsAnother bill pending in the Texas Senate could allow lawsuits against vaccine makers if their products cause harm, provided they advertise in Texas. This bill has faced strong opposition from business groups, including the Texas Association of Manufacturers.The proposal is led by Rep. Shelley Luther, known for defying COVID restrictions in 2020. Her push represents a broader movement questioning vaccine safety and government mandates.As Texas continues to recover from its ongoing outbreak, critics fear that easing exemption rules may put even more children and communities at risk.

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Just as the world had started settling into post-pandemic normalcy, <span>COVID-19</span> has reminded us again that it's not even close to being over. A new variant, NB.1.8.1, is making its way through global borders, already on its way to becoming a concern. With cases on the rise in China, Hong Kong, and Taiwan, this new variant has now been reported in the United States. Despite being overshadowed by declining public interest and lower testing, the virus is still mutating—becoming new variants such as NB.1.8.1 that require attention anew.

From respiratory signs to access to vaccines and worries about transmission, this latest turn of events adds one more chapter to the yet-unraveling COVID-19 saga. Let us dissect what exactly NB.1.8.1 is, just how dangerous it may be, and what you can do to safeguard yourself.

It’s been over four years since the world first encountered SARS-CoV-2 in Wuhan. Since then, we’ve witnessed a series of viral evolutions—from Alpha and Delta to Omicron and its subvariants. Each wave brought changes in transmissibility, symptoms, and vaccine response. The latest in this viral alphabet soup is NB.1.8.1—a subvariant of the XDV lineage.

NB.1.8.1 is patterned after its predecessors. It spreads fast and evolves to evade host immunity. Already, the variant has exploded in East Asia and is now appearing in the U.S., which the Centers for Disease Control and Prevention (CDC) confirmed. First detected late March and early April via international airport screening, its spread, although still in smaller numbers, is increasing in importance.

<h2>How NB.1.8.1 is Different From The Other Variants Presents?</h2>

There is dynamism in the viral ecosystem across the globe. Formerly dominant variants XEC and LF.7 are decreasing, while LP.8.1 holds the reins in North America, Europe, and regions of South America and South Africa. Gaining steam along with NB.1.8.1 is another upstart—XFG, a recombinant of LF.7 and LP.8.1.2—presently moving in Canada, the U.S., and Europe.

Based on global sequencing data, NB.1.8.1 represented 5% to 30% of non-North American samples by late April. Its geographic distribution appears to demonstrate a pattern of localized predominance—predominant in Asia but now increasingly found in North American datasets.

<h2>Symptoms of NB.1.8. COVID-19 Variant</h2>

NB.1.8.1 is not radically different in clinical presentation from prior strains. To date, symptoms described include:

<ol><li>Respiratory signs such as cough and sore throat</li><li>Systemic symptoms such as fatigue and fever</li></ol>

These symptoms mirror earlier forms of the virus, making early detection harder unless testing is actively pursued.

Even with higher hospitalizations in China and Hong Kong, experts warn that this might be a seasonal summer spike and not due to a more virulent NB.1.8.1 itself. Authorities have not established hard evidence the variant is worse, but any epidemic strain can overburden healthcare if it is not contained.

<h2>NB.1.8.: Who Needs to Be Worried and Risk Factors</h2>

As with prior strains, at greatest risk again are:

<ul><li>Older adults (65+)</li><li>Individuals with pre-existing medical conditions, such as diabetes, heart disease, or immunocompromised status</li><li>Pregnant women</li><li>Unvaccinated individuals</li></ul>

A note of concern is long COVID—continuing to impact thousands worldwide and often being precipitated by even minor infections. With every new variant comes more difficulty in comprehending how post-viral symptoms can change or intensify.

<h2>Who Gets the Fall COVID Booster Vaccine?</h2>

In a controversial and alarming move, the new U.S. administration led by HHS Secretary Robert F. Kennedy Jr. has indicated a limited rollout of new vaccine access. Although the FDA has licensed new COVID-19 boosters for the elderly and high-risk populations, the broader population might have to wait.

The FDA is now insisting on larger, longer-term clinical trials before introducing vaccines to the broader population, a move that postpones wider immunity and may accelerate transmission among younger, healthier adults.

The action comes as the NB.1.8.1 variant is picking up steam—whether it will be a force for good or a public health force to be reckoned with remains to be seen.

With vaccine supplies short and public health exhaustion widespread, personal prevention is key. Infectious disease specialists say that the following are some tried and tested strategies:

Wear masks in enclosed spaces where there is crowding, particularly if unwell or where there is known outbreak

Respiratory hygiene- cough into your elbow, sneeze into your elbow, wash hands frequently

Stay home when sick to limit transmission

Get tested upon exposure or showing symptoms, even mild ones

Hong Kong's public health authorities have also reintroduced mask advisories for high-risk groups, which marks the ongoing significance of non-pharmaceutical interventions.

With fewer individuals getting tested and a dismissal of mild symptoms, the risk of silent spreaders, those who are contagious but don't know it, continues to be a factor. And still, long COVID infects millions, leading to chronic fatigue, cognitive impairment, and respiratory problems. The more we let variants such as NB.1.8.1 spread without restraint, the more likely we are to have ongoing post-viral complications among all age groups.

While the world keeps moving, the virus has not. NB.1.8.1 is a reminder of how SARS-CoV-2 still evolves, disturbs, and commands notice. Being informed, careful, and proactive remains a necessity.

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Just as the world had started settling into post-pandemic normalcy, COVID-19 has reminded us again that it's not even close to being over. A new variant, NB.1.8.1, is making its way through global borders, already on its way to becoming a concern. With cases on the rise in China, Hong Kong, and Taiwan, this new variant has now been reported in the United States. Despite being overshadowed by declining public interest and lower testing, the virus is still mutating—becoming new variants such as NB.1.8.1 that require attention anew.From respiratory signs to access to vaccines and worries about transmission, this latest turn of events adds one more chapter to the yet-unraveling COVID-19 saga. Let us dissect what exactly NB.1.8.1 is, just how dangerous it may be, and what you can do to safeguard yourself.It’s been over four years since the world first encountered SARS-CoV-2 in Wuhan. Since then, we’ve witnessed a series of viral evolutions—from Alpha and Delta to Omicron and its subvariants. Each wave brought changes in transmissibility, symptoms, and vaccine response. The latest in this viral alphabet soup is NB.1.8.1—a subvariant of the XDV lineage.NB.1.8.1 is patterned after its predecessors. It spreads fast and evolves to evade host immunity. Already, the variant has exploded in East Asia and is now appearing in the U.S., which the Centers for Disease Control and Prevention (CDC) confirmed. First detected late March and early April via international airport screening, its spread, although still in smaller numbers, is increasing in importance.How NB.1.8.1 is Different From The Other Variants Presents?There is dynamism in the viral ecosystem across the globe. Formerly dominant variants XEC and LF.7 are decreasing, while LP.8.1 holds the reins in North America, Europe, and regions of South America and South Africa. Gaining steam along with NB.1.8.1 is another upstart—XFG, a recombinant of LF.7 and LP.8.1.2—presently moving in Canada, the U.S., and Europe.Based on global sequencing data, NB.1.8.1 represented 5% to 30% of non-North American samples by late April. Its geographic distribution appears to demonstrate a pattern of localized predominance—predominant in Asia but now increasingly found in North American datasets.Symptoms of NB.1.8. COVID-19 VariantNB.1.8.1 is not radically different in clinical presentation from prior strains. To date, symptoms described include:Respiratory signs such as cough and sore throatSystemic symptoms such as fatigue and feverThese symptoms mirror earlier forms of the virus, making early detection harder unless testing is actively pursued.Even with higher hospitalizations in China and Hong Kong, experts warn that this might be a seasonal summer spike and not due to a more virulent NB.1.8.1 itself. Authorities have not established hard evidence the variant is worse, but any epidemic strain can overburden healthcare if it is not contained.NB.1.8.: Who Needs to Be Worried and Risk FactorsAs with prior strains, at greatest risk again are:Older adults (65+)Individuals with pre-existing medical conditions, such as diabetes, heart disease, or immunocompromised statusPregnant womenUnvaccinated individualsA note of concern is long COVID—continuing to impact thousands worldwide and often being precipitated by even minor infections. With every new variant comes more difficulty in comprehending how post-viral symptoms can change or intensify.Who Gets the Fall COVID Booster Vaccine?In a controversial and alarming move, the new U.S. administration led by HHS Secretary Robert F. Kennedy Jr. has indicated a limited rollout of new vaccine access. Although the FDA has licensed new COVID-19 boosters for the elderly and high-risk populations, the broader population might have to wait.The FDA is now insisting on larger, longer-term clinical trials before introducing vaccines to the broader population, a move that postpones wider immunity and may accelerate transmission among younger, healthier adults.The action comes as the NB.1.8.1 variant is picking up steam—whether it will be a force for good or a public health force to be reckoned with remains to be seen.What Can You Do to Stay Safe?With vaccine supplies short and public health exhaustion widespread, personal prevention is key. Infectious disease specialists say that the following are some tried and tested strategies:Wear masks in enclosed spaces where there is crowding, particularly if unwell or where there is known outbreakRespiratory hygiene- cough into your elbow, sneeze into your elbow, wash hands frequentlyStay home when sick to limit transmissionGet tested upon exposure or showing symptoms, even mild onesHong Kong's public health authorities have also reintroduced mask advisories for high-risk groups, which marks the ongoing significance of non-pharmaceutical interventions.With fewer individuals getting tested and a dismissal of mild symptoms, the risk of silent spreaders, those who are contagious but don't know it, continues to be a factor. And still, long COVID infects millions, leading to chronic fatigue, cognitive impairment, and respiratory problems. The more we let variants such as NB.1.8.1 spread without restraint, the more likely we are to have ongoing post-viral complications among all age groups.While the world keeps moving, the virus has not. NB.1.8.1 is a reminder of how SARS-CoV-2 still evolves, disturbs, and commands notice. Being informed, careful, and proactive remains a necessity.

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Heart attacks are often portrayed as sudden and unmistakable — crushing chest pain, gasping for breath, collapsing to the ground. But for many, especially women, the signs can be far more subtle. A recent case from Houston, Texas, has reignited the conversation around the often-overlooked symptoms of heart attacks and how misinterpreting them can delay life-saving treatment.

Nikki, a 46-year-old woman with no previous medical conditions, took to TikTok to share her personal story of surviving a heart attack. Her message? “Listen to your body.” What seemed like ordinary aches and fatigue turned out to be her body’s warning signals — ones she initially brushed off as symptoms of perimenopause.

Nikki’s story begins a week before her heart attack — with nothing more than a sore shoulder.

“It felt like I slept on it wrong,” she explained in a TikTok video that has now garnered over 7.5 million views. Like many women navigating their 40s, she chalked it up to perimenopause, suspecting a “frozen shoulder,” which is often associated with hormonal changes. The pain, while noticeable, didn’t alarm her.

But the next day, the discomfort persisted. More concerningly, it was accompanied by a wave of nausea that lasted about 15 minutes. Again, Nikki shook it off and resumed her daily routine.

On the morning of her heart attack, Nikki experienced the same dull shoulder ache and another wave of nausea. This time, though, things escalated. Her chest began to feel tight — a deep, squeezing sensation — and the shoulder pain started radiating down her arm.

Still, trying not to overreact, she took a warm shower to ease her symptoms. She felt better afterward and even proceeded to a doctor’s appointment for an unrelated issue.

At the clinic, Nikki recounted her symptoms and asked if she should go to the emergency room. The doctor told her that unless the symptoms reappeared, an ER visit might not be necessary. Reassured but uncertain, she left. That decision nearly cost her life.

Just an hour later, as she stepped out of a restaurant after lunch, Nikki’s symptoms returned with alarming intensity.

“My chest felt like it was being squeezed as tight as you could squeeze it. The pain was now radiating all the way down my arm. I started sweating profusely,” she recalled.

Realizing the gravity of the moment, Nikki drove herself to the ER — just one street away. She walked up to the counter and said, “I need someone to look at my heart right this second.” A nurse saw her trembling and rushed her into care. Within minutes, doctors confirmed she was in the midst of a heart attack.

Quick action saved her life. But her story reveals how easy it is to ignore — or misdiagnose — early signs, especially in women without known risk factors.

Nikki’s experience underscores a well-documented issue in cardiovascular health: women often experience different, less-recognized symptoms of heart attacks compared to men. While classic signs such as chest pain, shortness of breath, and left-arm pain are common in men, women may experience:

Because these symptoms don’t match the stereotypical heart attack portrayal, they’re often mistaken for other conditions like anxiety, menopause, acid reflux, or even the flu.

In Nikki’s case, shoulder pain and nausea were the warning bells — but they were too easy to dismiss until it was almost too late.

Why Heart Attack is A Rising Trend Among the Under-50s?

Heart disease has long been associated with older adults, but recent trends show an unsettling rise in heart attacks among those under 50 — especially women. In the UK alone, more than 2 million people are diagnosed with heart disease, and millions more live with undiagnosed high blood pressure, a leading risk factor.

Data from both the UK and US indicate that heart attacks in younger adults are increasing, driven by a blend of risk factors including:

What’s more, post-COVID delays in diagnostics, treatment, and even emergency response times have only worsened outcomes for younger patients.

Nikki’s case remains medically puzzling. Tests found no blockages or plaque buildup in her arteries — a common cause of heart attacks. Instead, a women’s heart specialist at The Texas Heart Institute attributed the event to a “perfect storm” — a combination of perimenopausal hormonal changes and a recent illness that may have inflamed her heart.

“She does not believe there’s a strong genetic link at this time,” Nikki shared. However, follow-up scans suggest she may have sustained some permanent damage to her heart, and she continues to undergo further testing and care.

Nikki’s viral TikTok struck a chord globally. Not only did it help other women connect the dots between vague symptoms and serious cardiac risks, but it also opened up a wider dialogue about how we talk about — and treat — women’s <span>heart health</span>.

In the comments, many thanked her for sharing symptoms that might have otherwise gone unnoticed. Others expressed alarm at how easily the signs could be brushed off.

In Nikki’s own words: “Had I not been one street away from the ER, I might not be here telling this story.”

This story serves as a stark reminder that heart attacks don’t always look like they do in movies — and they certainly don’t only happen to older men with a history of heart disease.

If you experience unusual fatigue, persistent shoulder or chest discomfort, nausea, or any new and unexplained symptoms, don’t wait. Trust your instincts. Seek medical attention immediately — even if you’re “too young,” “too healthy,” or “too busy.”

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Heart attacks are often portrayed as sudden and unmistakable — crushing chest pain, gasping for breath, collapsing to the ground. But for many, especially women, the signs can be far more subtle. A recent case from Houston, Texas, has reignited the conversation around the often-overlooked symptoms of heart attacks and how misinterpreting them can delay life-saving treatment.Nikki, a 46-year-old woman with no previous medical conditions, took to TikTok to share her personal story of surviving a heart attack. Her message? “Listen to your body.” What seemed like ordinary aches and fatigue turned out to be her body’s warning signals — ones she initially brushed off as symptoms of perimenopause.Nikki’s story begins a week before her heart attack — with nothing more than a sore shoulder.“It felt like I slept on it wrong,” she explained in a TikTok video that has now garnered over 7.5 million views. Like many women navigating their 40s, she chalked it up to perimenopause, suspecting a “frozen shoulder,” which is often associated with hormonal changes. The pain, while noticeable, didn’t alarm her.But the next day, the discomfort persisted. More concerningly, it was accompanied by a wave of nausea that lasted about 15 minutes. Again, Nikki shook it off and resumed her daily routine.On the morning of her heart attack, Nikki experienced the same dull shoulder ache and another wave of nausea. This time, though, things escalated. Her chest began to feel tight — a deep, squeezing sensation — and the shoulder pain started radiating down her arm.Still, trying not to overreact, she took a warm shower to ease her symptoms. She felt better afterward and even proceeded to a doctor’s appointment for an unrelated issue.At the clinic, Nikki recounted her symptoms and asked if she should go to the emergency room. The doctor told her that unless the symptoms reappeared, an ER visit might not be necessary. Reassured but uncertain, she left. That decision nearly cost her life.Just an hour later, as she stepped out of a restaurant after lunch, Nikki’s symptoms returned with alarming intensity.“My chest felt like it was being squeezed as tight as you could squeeze it. The pain was now radiating all the way down my arm. I started sweating profusely,” she recalled.Realizing the gravity of the moment, Nikki drove herself to the ER — just one street away. She walked up to the counter and said, “I need someone to look at my heart right this second.” A nurse saw her trembling and rushed her into care. Within minutes, doctors confirmed she was in the midst of a heart attack.Quick action saved her life. But her story reveals how easy it is to ignore — or misdiagnose — early signs, especially in women without known risk factors.Nikki’s experience underscores a well-documented issue in cardiovascular health: women often experience different, less-recognized symptoms of heart attacks compared to men. While classic signs such as chest pain, shortness of breath, and left-arm pain are common in men, women may experience:FatigueIndigestion or nauseaPain in the jaw, back, or shoulderLightheadednessCold sweatsBecause these symptoms don’t match the stereotypical heart attack portrayal, they’re often mistaken for other conditions like anxiety, menopause, acid reflux, or even the flu.In Nikki’s case, shoulder pain and nausea were the warning bells — but they were too easy to dismiss until it was almost too late.Why Heart Attack is A Rising Trend Among the Under-50s?Heart disease has long been associated with older adults, but recent trends show an unsettling rise in heart attacks among those under 50 — especially women. In the UK alone, more than 2 million people are diagnosed with heart disease, and millions more live with undiagnosed high blood pressure, a leading risk factor.Data from both the UK and US indicate that heart attacks in younger adults are increasing, driven by a blend of risk factors including:ObesitySedentary lifestylesHigh blood pressureDiabetesChronic stressPoor dietWhat’s more, post-COVID delays in diagnostics, treatment, and even emergency response times have only worsened outcomes for younger patients.Nikki’s case remains medically puzzling. Tests found no blockages or plaque buildup in her arteries — a common cause of heart attacks. Instead, a women’s heart specialist at The Texas Heart Institute attributed the event to a “perfect storm” — a combination of perimenopausal hormonal changes and a recent illness that may have inflamed her heart.“She does not believe there’s a strong genetic link at this time,” Nikki shared. However, follow-up scans suggest she may have sustained some permanent damage to her heart, and she continues to undergo further testing and care.Nikki’s viral TikTok struck a chord globally. Not only did it help other women connect the dots between vague symptoms and serious cardiac risks, but it also opened up a wider dialogue about how we talk about — and treat — women’s heart health.In the comments, many thanked her for sharing symptoms that might have otherwise gone unnoticed. Others expressed alarm at how easily the signs could be brushed off.In Nikki’s own words: “Had I not been one street away from the ER, I might not be here telling this story.”This story serves as a stark reminder that heart attacks don’t always look like they do in movies — and they certainly don’t only happen to older men with a history of heart disease.If you experience unusual fatigue, persistent shoulder or chest discomfort, nausea, or any new and unexplained symptoms, don’t wait. Trust your instincts. Seek medical attention immediately — even if you’re “too young,” “too healthy,” or “too busy.”

heart attack signs you might miss: woman shares warning signs she felt a week before

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