Health and Me

Tanya Dutt

World Autism Day: Could Play Therapy Do What Traditional Autism Treatments Can’t?

World <span><a href="https://www.healthandme.com/health/autism">Autism</a></span> Awareness Day commemorates the period set aside to develop insight and promote solutions for those with <span>autism spectrum disorder</span> (ASD). Although the classic therapies of applied behavior analysis (ABA), speech therapy, and occupational therapy have been the standard intervention for autism, there has been an increasing interest in a different method: play therapy. Advoctates purport that play therapy stimulates a child's intrinsic method of acquiring knowledge, supporting communication, interpersonal skills, and emotional balance more effectively than can often be provided by mainstream interventions. Is play therapy the secret ingredient of autism intervention?

Autism Spectrum Disorder (ASD) impacts a child's capacity to communicate, socialize, and use imaginative play. Compared to neurotypical children, autistic children tend to have difficulties with pretend play and usually have a strong interest in particular activities. With these difficulties in mind, therapeutic interventions that address their needs are highly important. One of these interventions is play therapy, which is a structured but fun means of helping autistic children acquire vital life skills.

Play is the language of children, being a universal way of communication and learning. The Association for Play Therapy (APT) describes play therapy as the "systematic use of a theoretical model to establish an interpersonal process wherein trained play therapists use the therapeutic powers of play to help clients prevent or resolve psychosocial difficulties and achieve optimal growth and development." (APT, 2021).

In autistic children, play therapy provides a fun and organized setting to understand feelings, rehearse social interactions, and improve communication. A professional therapist helps the child progress through play-based strategies that promote self-expression and establish healthy relationships with parents, siblings, and friends.

<h2>Why Play Therapy Works for Autistic Children?</h2>

Play therapy is especially effective for children with ASD because it works within their natural learning and interaction style. It offers a low-stress, safe space in which children can:

<ul><li>Learn <span rel="noindex">social skills</span> like turn-taking and understanding nonverbal communication.</li><li>Enhance communication through verbal and nonverbal interaction.</li><li>Learn to regulate emotions in order to cope with frustration and anxiety.</li><li>Develop problem-solving and cognitive flexibility.</li><li>Decrease anxiety and build confidence in social situations.</li></ul>

Because autistic children tend to interact with play differently—e.g., becoming fixated on the components of a toy instead of the object as a whole or having difficulty with pretend play—therapists employ systematic methods to enable them to connect with their environment and the individuals in it.

<h2>Types of <span rel="noindex">Play Therapy for Autism</span></h2>

Play therapy involves a variety of methods adapted to a child's individual needs. Some of the most useful types for autistic children are:

<h4>Child-Centered Play Therapy (CCPT)</h4>

CCPT emphasizes establishing a nonjudgmental and accepting environment in which children are able to express themselves spontaneously. The therapist becomes the facilitator, with the child selecting activities of play while being treated with empathy and acceptance. This creates an atmosphere of safety and trust, with children able to explore their emotions and build up social skills organically.

Unlike CCPT, structured play therapy involves specific activities designed to target particular developmental goals. These sessions help autistic children develop essential skills in a step-by-step manner, ensuring they feel comfortable and supported.

<h4>Cognitive Behavioral Play Therapy (CBPT)</h4>

CBPT is an integration of cognitive behavioral therapy (CBT) with play therapy to assist children in identifying and managing their emotions. CBPT is particularly beneficial for children experiencing anxiety, frustration, or challenges with the adaptation to new circumstances.

<h2>Benefits of Play Therapy for Children with Autism</h2>

Play therapy allows autistic children to exercise verbal and nonverbal communication. By means of spoken language, gestures, or interactive stories, children become more at ease with self-expression.

Through play with a guide, children exercise basic social skills like turn-taking, sharing, and reading body language. These social skills enable them to develop more positive relationships with family members and peers.

<h4>Emotional Regulation and Coping Strategies</h4>

Play therapy provides a secure environment where children can experiment and learn to deal with their feelings. Therapists can demonstrate skills like deep breathing or the use of a "calm-down" toy to assist children in dealing with frustration and stress.

<h4>Problem-Solving and Cognitive Flexibility</h4>

Structured play activities encourage children to think creatively, adapt to new scenarios, and develop planning skills. This can be particularly helpful in improving their ability to adjust to changing routines or social expectations.

<h4>Reduced Anxiety and Increased Confidence</h4>

By providing a playful and interactive setting, play therapy makes autistic children less apprehensive about social interactions and new experiences. Gradually, this increases their confidence and readiness to interact with the world around them.

<h2>Play Therapy Activities for Autistic Children</h2>

Including therapeutic play activities at home can further increase the advantages of professional play therapy. Some ideas include:

Obstacle Course: Create an indoor obstacle course with pillows, chairs, and painter's tape. Have your child jump, spin, and crawl through the various sections to promote coordination and sensory integration.

Tilt a Ball: Cut a hole at the bottom of a cardboard box to make a basic ball maze. Have your child tilt the box to direct the ball through the maze to develop hand-eye coordination.

Free the Animals: Secure plastic toy animals with painter’s tape and have your child peel them off to strengthen fine motor skills.

Clay Sculpting: Use therapy putty or clay to model different shapes or animals, enhancing dexterity and creativity.

<h4>Interactive and Group Play Activities</h4>

Scavenger Hunt: Create a themed scavenger hunt to encourage problem-solving and exploration.

Ribbon Wand Dancing: Place ribbons on wooden spoons and invite dancing to music, enhancing gross motor skills and sensory awareness.

Row, Row, Row Your Boat: A cooperative game wherein children rock back and forth as they sing, enhancing cooperative play and rhythmic movement.

Parent participation is essential to the success of play therapy. By attending therapy sessions and applying learned skills in everyday life, parents can support gains and create further opportunities for development. Parents are frequently taught by therapists to use play-based strategies to facilitate communication, emotional control, and social interaction within the home environment.

<h2>Choosing the Right Play Therapy for Your Child</h2>

When selecting a play therapist, keep the following in mind:

Credentials: Seek professionals who hold a psychology, social work, or counseling degree, and play therapy certifications (e.g., Registered Play Therapist, RPT).

Experience: Opt for a therapist experienced in treating autistic children, as they will have in-depth knowledge of ASD-specific issues.

Approach: Talk to various therapy approaches to select the one that will best suit your child's needs and personality.

<h2>How Can Parents Support Play Therapy at Home?</h2>

To ensure maximum returns from play therapy, parents can:

<ul><li>Encourage play learning: Integrate therapy skills into daily life.</li><li>Design a supportive play environment: Create a quiet, stimulating area with sensory-friendly materials.</li><li>Learn from sessions: Use therapist-recommended techniques to build on progress in the home environment.</li></ul>

Play therapy is an effective intervention for autistic children, providing a natural and fun means of establishing communication, social, and emotional skills. With the help of trained therapists and the integration of play-based strategies at home, parents can facilitate their children in acquiring key life skills in a fun and nurturing environment. Consulting professional services and remaining actively engaged in the therapy process ensures that autistic children get the assistance they require to flourish.

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World Autism Awareness Day commemorates the period set aside to develop insight and promote solutions for those with autism spectrum disorder (ASD). Although the classic therapies of applied behavior analysis (ABA), speech therapy, and occupational therapy have been the standard intervention for autism, there has been an increasing interest in a different method: play therapy. Advoctates purport that play therapy stimulates a child's intrinsic method of acquiring knowledge, supporting communication, interpersonal skills, and emotional balance more effectively than can often be provided by mainstream interventions. Is play therapy the secret ingredient of autism intervention?Autism Spectrum Disorder (ASD) impacts a child's capacity to communicate, socialize, and use imaginative play. Compared to neurotypical children, autistic children tend to have difficulties with pretend play and usually have a strong interest in particular activities. With these difficulties in mind, therapeutic interventions that address their needs are highly important. One of these interventions is play therapy, which is a structured but fun means of helping autistic children acquire vital life skills.Play is the language of children, being a universal way of communication and learning. The Association for Play Therapy (APT) describes play therapy as the "systematic use of a theoretical model to establish an interpersonal process wherein trained play therapists use the therapeutic powers of play to help clients prevent or resolve psychosocial difficulties and achieve optimal growth and development." (APT, 2021).In autistic children, play therapy provides a fun and organized setting to understand feelings, rehearse social interactions, and improve communication. A professional therapist helps the child progress through play-based strategies that promote self-expression and establish healthy relationships with parents, siblings, and friends.Why Play Therapy Works for Autistic Children?Play therapy is especially effective for children with ASD because it works within their natural learning and interaction style. It offers a low-stress, safe space in which children can:Learn social skills like turn-taking and understanding nonverbal communication.Enhance communication through verbal and nonverbal interaction.Learn to regulate emotions in order to cope with frustration and anxiety.Develop problem-solving and cognitive flexibility.Decrease anxiety and build confidence in social situations.Because autistic children tend to interact with play differently—e.g., becoming fixated on the components of a toy instead of the object as a whole or having difficulty with pretend play—therapists employ systematic methods to enable them to connect with their environment and the individuals in it.Types of Play Therapy for AutismPlay therapy involves a variety of methods adapted to a child's individual needs. Some of the most useful types for autistic children are:Child-Centered Play Therapy (CCPT)CCPT emphasizes establishing a nonjudgmental and accepting environment in which children are able to express themselves spontaneously. The therapist becomes the facilitator, with the child selecting activities of play while being treated with empathy and acceptance. This creates an atmosphere of safety and trust, with children able to explore their emotions and build up social skills organically.Structured Play TherapyUnlike CCPT, structured play therapy involves specific activities designed to target particular developmental goals. These sessions help autistic children develop essential skills in a step-by-step manner, ensuring they feel comfortable and supported.Cognitive Behavioral Play Therapy (CBPT)CBPT is an integration of cognitive behavioral therapy (CBT) with play therapy to assist children in identifying and managing their emotions. CBPT is particularly beneficial for children experiencing anxiety, frustration, or challenges with the adaptation to new circumstances.Benefits of Play Therapy for Children with AutismEnhanced Communication SkillsPlay therapy allows autistic children to exercise verbal and nonverbal communication. By means of spoken language, gestures, or interactive stories, children become more at ease with self-expression.Increased Social InteractionThrough play with a guide, children exercise basic social skills like turn-taking, sharing, and reading body language. These social skills enable them to develop more positive relationships with family members and peers.Emotional Regulation and Coping StrategiesPlay therapy provides a secure environment where children can experiment and learn to deal with their feelings. Therapists can demonstrate skills like deep breathing or the use of a "calm-down" toy to assist children in dealing with frustration and stress.Problem-Solving and Cognitive FlexibilityStructured play activities encourage children to think creatively, adapt to new scenarios, and develop planning skills. This can be particularly helpful in improving their ability to adjust to changing routines or social expectations.Reduced Anxiety and Increased ConfidenceBy providing a playful and interactive setting, play therapy makes autistic children less apprehensive about social interactions and new experiences. Gradually, this increases their confidence and readiness to interact with the world around them.Play Therapy Activities for Autistic ChildrenIncluding therapeutic play activities at home can further increase the advantages of professional play therapy. Some ideas include:Gross Motor GamesObstacle Course: Create an indoor obstacle course with pillows, chairs, and painter's tape. Have your child jump, spin, and crawl through the various sections to promote coordination and sensory integration.Tilt a Ball: Cut a hole at the bottom of a cardboard box to make a basic ball maze. Have your child tilt the box to direct the ball through the maze to develop hand-eye coordination.Fine Motor GamesFree the Animals: Secure plastic toy animals with painter’s tape and have your child peel them off to strengthen fine motor skills.Clay Sculpting: Use therapy putty or clay to model different shapes or animals, enhancing dexterity and creativity.Interactive and Group Play ActivitiesScavenger Hunt: Create a themed scavenger hunt to encourage problem-solving and exploration.Ribbon Wand Dancing: Place ribbons on wooden spoons and invite dancing to music, enhancing gross motor skills and sensory awareness.Row, Row, Row Your Boat: A cooperative game wherein children rock back and forth as they sing, enhancing cooperative play and rhythmic movement.Role of Parents in Play TherapyParent participation is essential to the success of play therapy. By attending therapy sessions and applying learned skills in everyday life, parents can support gains and create further opportunities for development. Parents are frequently taught by therapists to use play-based strategies to facilitate communication, emotional control, and social interaction within the home environment.Choosing the Right Play Therapy for Your ChildWhen selecting a play therapist, keep the following in mind:Credentials: Seek professionals who hold a psychology, social work, or counseling degree, and play therapy certifications (e.g., Registered Play Therapist, RPT).Experience: Opt for a therapist experienced in treating autistic children, as they will have in-depth knowledge of ASD-specific issues.Approach: Talk to various therapy approaches to select the one that will best suit your child's needs and personality.How Can Parents Support Play Therapy at Home?To ensure maximum returns from play therapy, parents can:Encourage play learning: Integrate therapy skills into daily life.Design a supportive play environment: Create a quiet, stimulating area with sensory-friendly materials.Learn from sessions: Use therapist-recommended techniques to build on progress in the home environment.Play therapy is an effective intervention for autistic children, providing a natural and fun means of establishing communication, social, and emotional skills. With the help of trained therapists and the integration of play-based strategies at home, parents can facilitate their children in acquiring key life skills in a fun and nurturing environment. Consulting professional services and remaining actively engaged in the therapy process ensures that autistic children get the assistance they require to flourish.

world autism day: could play therapy do what traditional autism treatments can’t?

Ishita Roy

Warning Letter Sent To Companies Selling Illegal Opioid Compound

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In a significant move to safeguard public health, the U.S. Food and Drug Administration (<span>FDA</span>) has issued warning letters to seven companies accused of illegally marketing products containing a powerful compound found in kratom, known as 7-hydroxymitragynine (7-OH). These companies have been selling concentrated versions of the substance in forms like tablets, gummies, drink mixes, and energy shots—many of which are available online and in everyday retail outlets such as smoke shops, gas stations, and convenience stores.

<h4>What Is 7-OH and Why Is It a Concern?</h4>

7-hydroxymitragynine is a chemical compound that naturally occurs in very small quantities in the kratom plant. However, in these commercial products, it is either added in high concentrations or manipulated to raise the levels well beyond natural amounts. The problem? 7-OH is not approved by the FDA for use in any dietary supplement, conventional food, or pharmaceutical drug.

According to the agency, not only does this make these products illegal, but it also raises serious health and safety concerns. The FDA emphasized that the compound has not been proven safe or effective for treating any health condition and warned that consumers using these products are putting themselves at risk.

<h4>Illegal and Unsubstantiated Claims</h4>

The companies receiving the warning letters were accused of marketing their 7-OH products with unproven claims about treating pain, anxiety, and other medical conditions. Some of these products are being sold as dietary supplements or even regular food items, despite not meeting the legal or scientific safety standards required for such classifications.

The FDA’s main concern lies in how these products are being presented to the public—as safe, natural remedies—when in fact they may be both unsafe and illegal. “People using these products are exposing themselves to substances that have not been proven safe or effective for any use,” the FDA warned in a statement.

The seven companies that have been sent official warning letters include:

<ul><li>Shaman Botanicals LLC</li><li>My Smoke Wholesale</li><li>Relax Relief Rejuvenate Trading LLC (also known as RRR Trading or EDP Kratom)</li><li>Thang Botanicals Inc. (doing business as 7ΩHMZ, 7-OHMZ, or 7OHMZ)</li><li>Royal Diamond Imports Inc. (operating Roxytabs.com)</li><li>Hydroxie LLC</li><li>7Tabz Retail LLC</li></ul>

All seven companies have been given 15 business days to respond to the FDA’s concerns. They are required to outline what actions they will take to correct the violations. Failure to respond or take corrective measures could lead to further enforcement actions, including product seizures or legal injunctions.

This latest crackdown reflects the FDA’s ongoing concerns around kratom and its derivatives, particularly products containing high concentrations of 7-OH. Consumers are urged to avoid such products and consult healthcare professionals before using any substance marketed as a pain or anxiety remedy.

The agency continues to monitor the market and has signaled it will take further steps if necessary to protect the public from unsafe, misbranded, or illegally marketed products.

FDA sent warning letter

health and wellness

opioid

FDA warning

In a significant move to safeguard public health, the U.S. Food and Drug Administration (FDA) has issued warning letters to seven companies accused of illegally marketing products containing a powerful compound found in kratom, known as 7-hydroxymitragynine (7-OH). These companies have been selling concentrated versions of the substance in forms like tablets, gummies, drink mixes, and energy shots—many of which are available online and in everyday retail outlets such as smoke shops, gas stations, and convenience stores.What Is 7-OH and Why Is It a Concern?7-hydroxymitragynine is a chemical compound that naturally occurs in very small quantities in the kratom plant. However, in these commercial products, it is either added in high concentrations or manipulated to raise the levels well beyond natural amounts. The problem? 7-OH is not approved by the FDA for use in any dietary supplement, conventional food, or pharmaceutical drug.According to the agency, not only does this make these products illegal, but it also raises serious health and safety concerns. The FDA emphasized that the compound has not been proven safe or effective for treating any health condition and warned that consumers using these products are putting themselves at risk.Illegal and Unsubstantiated ClaimsThe companies receiving the warning letters were accused of marketing their 7-OH products with unproven claims about treating pain, anxiety, and other medical conditions. Some of these products are being sold as dietary supplements or even regular food items, despite not meeting the legal or scientific safety standards required for such classifications.The FDA’s main concern lies in how these products are being presented to the public—as safe, natural remedies—when in fact they may be both unsafe and illegal. “People using these products are exposing themselves to substances that have not been proven safe or effective for any use,” the FDA warned in a statement.The Companies NamedThe seven companies that have been sent official warning letters include:Shaman Botanicals LLCMy Smoke WholesaleRelax Relief Rejuvenate Trading LLC (also known as RRR Trading or EDP Kratom)Thang Botanicals Inc. (doing business as 7ΩHMZ, 7-OHMZ, or 7OHMZ)Royal Diamond Imports Inc. (operating Roxytabs.com)Hydroxie LLC7Tabz Retail LLCAll seven companies have been given 15 business days to respond to the FDA’s concerns. They are required to outline what actions they will take to correct the violations. Failure to respond or take corrective measures could lead to further enforcement actions, including product seizures or legal injunctions.FDA Urges CautionThis latest crackdown reflects the FDA’s ongoing concerns around kratom and its derivatives, particularly products containing high concentrations of 7-OH. Consumers are urged to avoid such products and consult healthcare professionals before using any substance marketed as a pain or anxiety remedy.The agency continues to monitor the market and has signaled it will take further steps if necessary to protect the public from unsafe, misbranded, or illegally marketed products.

warning letter sent to companies selling illegal opioid compound

Ozempic, Wegovy Aren't Magic, These 5 Body Traits Predict If You’ll Actually Lose Weight

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For anyone who's been following the meteoric rise of weight-loss injections like Ozempic and Wegovy, one thing is certain: these medications are effective but not for everyone. Now, a new, in-depth study might know why.

Appearing in the journal Diabetes, Obesity and Metabolism, this new research has identified key determinants of who is most likely to thrive on GLP-1 receptor agonists (GLP-1RAs), a drug class that includes semaglutide (Ozempic/Wegovy). Ranging from use duration to body composition, and from metabolic rate to diabetic status, the results yield a finer set of directions for individualized obesity treatment—and may potentially minimize the guesswork that too often vexes patients and clinicians alike.

GLP-1RAs are drugs initially made to treat type 2 diabetes but have produced miraculous outcomes for the treatment of obesity. They function by duplicating a hormone that occurs naturally in the body, which suppresses hunger and controls the blood sugar levels. Semaglutide, the drug behind Ozempic and Wegovy, has assisted individuals in losing an average of 15–21% of their body weight when combined with diet and lifestyle modifications.

Even with all the news-grabbing changes and social media hype, results are all over the place. Some patients lose weight rapidly, others plateau, and some develop side effects such as nausea that cause them to quit cold turkey. The new research, performed at Peking University People's Hospital, sheds some light on why.

Scientists monitored 679 overweight or obese patients who initiated GLP-1RA treatment between November 2022 and October 2024 at an obesity clinic in Beijing. For 12 months, they monitored a range of physical and metabolic factors to determine what characteristics were associated with improved outcomes.

Patients taking GLP-1RAs for extended periods, particularly semaglutide, had higher odds of significant <span>weight loss</span>. But more than how long the patient was on the drug, study authors determined that individual traits mattered substantially in effectiveness.

In particular, individuals who did not have diabetes, had a higher percentage of body fat, larger amounts of skeletal muscle, and a higher rate of basal metabolism were found to be more likely to succeed. Also, higher serum creatinine levels (a marker for muscle mass and kidney function) were associated with improved success.

<h2>Role of Muscle Mass and Metabolism</h2>

GLP-1s are effective devices, but they need to be combined with muscle-sparing measures. Most patients inadvertently lose lean muscle mass, which can lower metabolism and undermine long-term weight control.

That is, the scale may fall, but what you lose is important. Retaining muscle mass is essential to long-term health and success. Because of this, experts suggest a two-prong approach: savvy, high-protein eating and regular strength training to help maintain lean tissue throughout treatment.

<h2>5 Body Traits That Predict If You'll Actually Lose Weight on GLP-1 Drugs</h2>

New research is showing that not everyone responds the same way to GLP-1 receptor agonists—and your body’s makeup may be the key to understanding why. Here are five physical traits that strongly predict whether you’ll shed pounds successfully while on these weight-loss medications:

Individuals with excess body fat at the beginning of treatment respond to GLP-1 drugs more favorably. Why? They attack hunger and fat storage, so people with more to lose are more likely to see faster and more dramatic results.

<h4>2. Increased Skeletal Muscle Mass</h4>

Muscle is not only for power—it burns calories even at rest. Individuals with greater skeletal muscle mass (particularly in the arms, legs, and abdomen) tend to have a quicker metabolism, which can strengthen the actions of weight-loss drugs.

<h4>3. Increased Basal Metabolic Rate (BMR)</h4>

A greater BMR indicates that your body expends more energy on a daily basis. Individuals with naturally quicker metabolisms are more apt to experience efficient and long-lasting weight loss when taking GLP-1RAs such as semaglutide.

<h4>4. Greater Serum Creatinine Levels</h4>

This marker is most commonly associated with muscle mass and kidney function. Individuals with slightly elevated (but normal) levels of creatinine—usually an indicator of greater lean body mass—tended to respond more favorably to these drugs.

Against expectation, individuals with no diabetes experienced more success than those with diabetes. This could be explained by improved insulin sensitivity, reduced metabolic resistance, or fewer pre-existing complications that would interfere with weight reduction.

<h2>How Your Diabetes Status Is Important?</h2>

The research demonstrated that those without diabetes had considerably higher chances of being successful with weight loss compared to those with prediabetes or diabetes. This could be because of deep-rooted metabolic distinctions or that GLP-1RAs react differently in states of insulin resistance.

Lead researcher Dr. Linong Ji described, "This study highlights the value of metabolic state-matched strategies. Individuals with diabetes can benefit from a different or more combined regimen." 

Consistency is key, patients who remained on the drug for a longer period were more likely to lose weight. Those who dropped out early because of side effects, lack of response, or lifestyle interference were far less successful.

This accords with demands from doctors for improved support for adherence. Greater follow-up frequencies, tailored coaching, and symptom control can avert early dropouts.

"Adherence to medication is neglected but equally important as the medicine itself," the authors stated. "Physicians must assist patients in staying on track, especially for the first months or so."

Side effects, particularly gastrointestinal such as nausea, constipation, or vomiting, are still the number one reasons individuals drop out of GLP-1RAs. That's where tailoring treatment comes into play even more so.

Take, for instance, individuals who have less skeletal muscle mass. These individuals are likely to be more susceptible to fatigue and muscle wasting, enhancing dropout risk. Tweaking dose schedules, incorporating physical therapy, or emphasizing diet quality can all help mitigate these problems.

The global rise of drugs like Wegovy isn’t just hype. These medications are proving to be some of the most effective tools we’ve ever had in the fight against obesity, a condition affecting over 650 million people worldwide but what this new study makes clear is that weight loss is not one-size-fits-all, even with powerful drugs. Body composition, muscle mass, metabolic health, and individual biology all play a role.

For doctors, that equates to taking a precision medicine approach—tailoring treatments based on an individual's profile, instead of simply dosing all patients the same.

And for patients? It's a reminder that medications such as Ozempic and Wegovy can be remarkably powerful but only as part of an integrated, personalized plan that values the complexity of your body.

GLP-1 medications are revolutionizing weight control, but as this study reveals, success is not arbitrary success is individual. Understanding what influences results can enable more individuals to achieve potential through progress.

weight loss

glp 1 weight loss

ozempic results

wegovy success factors

semaglutide weight loss study

personalized obesity treatment

weight loss and muscle mass

diabetes and weight loss drugs

For anyone who's been following the meteoric rise of weight-loss injections like Ozempic and Wegovy, one thing is certain: these medications are effective but not for everyone. Now, a new, in-depth study might know why.Appearing in the journal Diabetes, Obesity and Metabolism, this new research has identified key determinants of who is most likely to thrive on GLP-1 receptor agonists (GLP-1RAs), a drug class that includes semaglutide (Ozempic/Wegovy). Ranging from use duration to body composition, and from metabolic rate to diabetic status, the results yield a finer set of directions for individualized obesity treatment—and may potentially minimize the guesswork that too often vexes patients and clinicians alike.GLP-1RAs are drugs initially made to treat type 2 diabetes but have produced miraculous outcomes for the treatment of obesity. They function by duplicating a hormone that occurs naturally in the body, which suppresses hunger and controls the blood sugar levels. Semaglutide, the drug behind Ozempic and Wegovy, has assisted individuals in losing an average of 15–21% of their body weight when combined with diet and lifestyle modifications.Even with all the news-grabbing changes and social media hype, results are all over the place. Some patients lose weight rapidly, others plateau, and some develop side effects such as nausea that cause them to quit cold turkey. The new research, performed at Peking University People's Hospital, sheds some light on why.Scientists monitored 679 overweight or obese patients who initiated GLP-1RA treatment between November 2022 and October 2024 at an obesity clinic in Beijing. For 12 months, they monitored a range of physical and metabolic factors to determine what characteristics were associated with improved outcomes.Patients taking GLP-1RAs for extended periods, particularly semaglutide, had higher odds of significant weight loss. But more than how long the patient was on the drug, study authors determined that individual traits mattered substantially in effectiveness.In particular, individuals who did not have diabetes, had a higher percentage of body fat, larger amounts of skeletal muscle, and a higher rate of basal metabolism were found to be more likely to succeed. Also, higher serum creatinine levels (a marker for muscle mass and kidney function) were associated with improved success.Role of Muscle Mass and MetabolismGLP-1s are effective devices, but they need to be combined with muscle-sparing measures. Most patients inadvertently lose lean muscle mass, which can lower metabolism and undermine long-term weight control.That is, the scale may fall, but what you lose is important. Retaining muscle mass is essential to long-term health and success. Because of this, experts suggest a two-prong approach: savvy, high-protein eating and regular strength training to help maintain lean tissue throughout treatment.5 Body Traits That Predict If You'll Actually Lose Weight on GLP-1 DrugsNew research is showing that not everyone responds the same way to GLP-1 receptor agonists—and your body’s makeup may be the key to understanding why. Here are five physical traits that strongly predict whether you’ll shed pounds successfully while on these weight-loss medications:1. Higher Body Fat PercentageIndividuals with excess body fat at the beginning of treatment respond to GLP-1 drugs more favorably. Why? They attack hunger and fat storage, so people with more to lose are more likely to see faster and more dramatic results.2. Increased Skeletal Muscle MassMuscle is not only for power—it burns calories even at rest. Individuals with greater skeletal muscle mass (particularly in the arms, legs, and abdomen) tend to have a quicker metabolism, which can strengthen the actions of weight-loss drugs.3. Increased Basal Metabolic Rate (BMR)A greater BMR indicates that your body expends more energy on a daily basis. Individuals with naturally quicker metabolisms are more apt to experience efficient and long-lasting weight loss when taking GLP-1RAs such as semaglutide.4. Greater Serum Creatinine LevelsThis marker is most commonly associated with muscle mass and kidney function. Individuals with slightly elevated (but normal) levels of creatinine—usually an indicator of greater lean body mass—tended to respond more favorably to these drugs.5. No Diagnosis of DiabetesAgainst expectation, individuals with no diabetes experienced more success than those with diabetes. This could be explained by improved insulin sensitivity, reduced metabolic resistance, or fewer pre-existing complications that would interfere with weight reduction.How Your Diabetes Status Is Important?The research demonstrated that those without diabetes had considerably higher chances of being successful with weight loss compared to those with prediabetes or diabetes. This could be because of deep-rooted metabolic distinctions or that GLP-1RAs react differently in states of insulin resistance.Lead researcher Dr. Linong Ji described, "This study highlights the value of metabolic state-matched strategies. Individuals with diabetes can benefit from a different or more combined regimen." Consistency is key, patients who remained on the drug for a longer period were more likely to lose weight. Those who dropped out early because of side effects, lack of response, or lifestyle interference were far less successful.This accords with demands from doctors for improved support for adherence. Greater follow-up frequencies, tailored coaching, and symptom control can avert early dropouts."Adherence to medication is neglected but equally important as the medicine itself," the authors stated. "Physicians must assist patients in staying on track, especially for the first months or so."Side Effects of GLP-1 DrugsSide effects, particularly gastrointestinal such as nausea, constipation, or vomiting, are still the number one reasons individuals drop out of GLP-1RAs. That's where tailoring treatment comes into play even more so.Take, for instance, individuals who have less skeletal muscle mass. These individuals are likely to be more susceptible to fatigue and muscle wasting, enhancing dropout risk. Tweaking dose schedules, incorporating physical therapy, or emphasizing diet quality can all help mitigate these problems.The global rise of drugs like Wegovy isn’t just hype. These medications are proving to be some of the most effective tools we’ve ever had in the fight against obesity, a condition affecting over 650 million people worldwide but what this new study makes clear is that weight loss is not one-size-fits-all, even with powerful drugs. Body composition, muscle mass, metabolic health, and individual biology all play a role.For doctors, that equates to taking a precision medicine approach—tailoring treatments based on an individual's profile, instead of simply dosing all patients the same.And for patients? It's a reminder that medications such as Ozempic and Wegovy can be remarkably powerful but only as part of an integrated, personalized plan that values the complexity of your body.GLP-1 medications are revolutionizing weight control, but as this study reveals, success is not arbitrary success is individual. Understanding what influences results can enable more individuals to achieve potential through progress.

ozempic, wegovy aren't magic, these 5 body traits predict if you’ll actually lose weight

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<span>Breast cancer</span> is one of the most treatable cancers when caught early. Yet, a significant number of women remain unclear about one of the most crucial tools for early detection: the mammogram. A new survey by the Annenberg Public Policy Center (APPC) reveals just how persistent and widespread the confusion is over when women should start getting screened. Despite updated national guidelines recommending mammograms beginning at age 40, nearly half of the adults surveyed in the US are either misinformed or confused.

The US Preventive Services Task Force (USPSTF) issued a revised recommendation in April 2024, advising that women at average risk of breast cancer begin screening mammograms every other year starting at age 40. This update rolled back an earlier guideline that suggested beginning at age 50, a shift that aligns more closely with what other medical bodies have long recommended.

The American Cancer Society, for instance, has consistently recommended that women aged 40 to 44 have the option to begin annual screening, with stronger guidance to start annually from age 45. By age 55, women can shift to screenings every other year.

But with a history of back-and-forth on these guidelines, public understanding hasn’t caught up.

"Confusion can arise when medical guidance about detection or treatment changes," said Kathleen Hall Jamieson, director of the APPC. “Our data suggest that the recommendation that such screening ordinarily start at 40 years old is not yet widely enough known.”

The APPC’s April 2024 survey sampled over 1,600 U.S. adults. The results were telling:

<ul><li>Only 49% correctly identified age 40 as the right age to begin biennial mammograms for women at average risk.</li><li>A notable 10% said screenings should begin at age 20, while 21% selected age 30. 8% said 50, and 11% admitted they were unsure.</li></ul>

Even more telling: this level of awareness remained unchanged from a previous survey conducted before the updated guidelines were published. So while the medical advice evolved, public understanding stood still.

<h2>Is Misinformation Creating Confusion?</h2>

Breast cancer is one of the most treatable cancers when caught early. Yet, a significant number of women remain unclear about one of the most crucial tools for early detection: the mammogram. A new survey by the Annenberg Public Policy Center (APPC) reveals just how persistent and widespread the confusion is over when women should start getting screened. Despite updated national guidelines recommending mammograms beginning at age 40, nearly half of the adults surveyed in the US are either misinformed or confused.The US Preventive Services Task Force (USPSTF) issued a revised recommendation in April 2024, advising that women at average risk of breast cancer begin screening mammograms every other year starting at age 40. This update rolled back an earlier guideline that suggested beginning at age 50, a shift that aligns more closely with what other medical bodies have long recommended.The American Cancer Society, for instance, has consistently recommended that women aged 40 to 44 have the option to begin annual screening, with stronger guidance to start annually from age 45. By age 55, women can shift to screenings every other year.But with a history of back-and-forth on these guidelines, public understanding hasn’t caught up."Confusion can arise when medical guidance about detection or treatment changes," said Kathleen Hall Jamieson, director of the APPC. “Our data suggest that the recommendation that such screening ordinarily start at 40 years old is not yet widely enough known.”The APPC’s April 2024 survey sampled over 1,600 U.S. adults. The results were telling:Only 49% correctly identified age 40 as the right age to begin biennial mammograms for women at average risk.A notable 10% said screenings should begin at age 20, while 21% selected age 30. 8% said 50, and 11% admitted they were unsure.Even more telling: this level of awareness remained unchanged from a previous survey conducted before the updated guidelines were published. So while the medical advice evolved, public understanding stood still.Is Misinformation Creating Confusion?Women aged 40–49 were the most informed demographic in the survey—72% of them knew screenings should begin at 40. But awareness dropped significantly among younger groups. Only 37% of women aged 18–29 knew the correct age to begin mammograms and a concerning 27% of that group mistakenly thought the correct age was 30, while 16% didn’t know at all.This gap in understanding matters because younger women especially those with family history or genetic predisposition, may need to start even earlier.What Are Mammograms?A mammogram is a low-dose X-ray that captures detailed images of breast tissue, capable of identifying cancers before any physical symptoms appear.In women with a BRCA1 or BRCA2 gene mutation who are referred to as "high risk" or with a history of radiation to the chest between ages 10 and 30, screening may start as early as age 30 and include annual breast MRIs alongside mammograms.Modern technology has made the process quicker and less painful. Better compression paddles, 3D mammograms, and AI-assisted readings now reduce both discomfort and the chance of error.Despite technological improvements, mammograms are not infallible. Their accuracy ranges between 85–90%, and performance can dip in women with dense breast tissue.Contrast-enhanced digital mammography (CEDM) is another newer innovation helping radiologists identify tricky cases. The integration of artificial intelligence is also streamlining diagnostic accuracy.Does 'Abnormal' Mammogram Mean Cancer?An abnormal mammogram result doesn’t necessarily mean breast cancer. It simply means something unusual has been spotted and warrants further testing, which could include a breast ultrasound, MRI, or even a biopsy.In the US, follow-up care is typically swift, with guidelines in place to ensure patients are informed and supported. However, disparities in healthcare access especially for uninsured or not populations still persist.The APPC survey’s findings highlight a deeper issue, how public health communication is struggling to keep up with shifting medical guidelines. When official recommendations change, the burden of clarity shouldn’t fall solely on the individual. It requires coordinated messaging across healthcare providers, public health agencies, insurers, and the media.While mammograms are widely available in the U.S., access isn’t always equitable. Low-income communities and communities of color often face hurdles ranging from cost and insurance barriers to logistical challenges like transportation or time off work.Breast cancer remains one of the leading causes of cancer death among women. Early detection significantly improves outcomes, but only if women are aware and empowered to begin screening at the appropriate time.If you're approaching 40, talk to your doctor about when to begin screening especially if you have additional risk factors. Don’t wait for symptoms to show up.