Thousands of women across the UK are waking up at 3am—something that health experts are blaming on their hormones. Dr Martin Thronton, while speaking to The Sun, said that menopause is a significant reason for their disrupted slumber. He explained that menopause represents a huge change for the body, and hormonal shifts can lead to a range of uncomfortable experiences that can largely impact sleep.While timings can differ for women to experience sleep disruptions, most of Dr Thornton's patients report waking up between 2 am to 4am, when the sleep is lighter. According to him, the main reason behind this is that body's timing or circadian rhythm matches with body's temperature regulation being disrupted from hot flushes or night sweats. Study Finds 3:29am To Be Most Common Wakeup TimeA study, conducted by British retailer Dunelm, found 3.29am to be the most common wake-up time for menopausal women, with three quarters of female participants stirring way before the country's average wake up time of 7am. It also found that nearly 53% of participants found themselves "tossing and turning until they manage to fall back asleep". Furthermore, about 69% of these women felt menopausal insomnia had an adverse effect on their emotional wellbeing.Can Men Be Affected Too?Research has found that hormones can wreak havoc on men's sleeping patterns too. The disruption in their slumber is largely dependent on their testosterone level, which declines as they grow older. Interestingly, health experts have noted that stress hormone Cortisol, affects everyone's sleep, regardless of their gender. How To Combat Disturbed Sleep?One of the most common and effective solution for menopausal women to combat this is Hormone Replacement Therapy (HTR). This treatment is widely used to alleviate menopause symptoms such as hot flashes, night sweats, and vaginal dryness. It works by restoring hormone levels—most commonly estrogen— which decline with age and contribute to various menopause-related symptoms. Options in the HRT can include estrogen, progesterone, and sometimes testosterone, depending on individual needs. However, debates regarding the safety and long-term effects of HRT continue."For many years women and healthcare professionals shied away from hormone therapy for fear of the potential adverse health effects. Studies like this are valuable to help women feel more confident about their decision to use hormone therapy for managing their bothersome menopause symptoms, especially hot flashes," Dr Stephanie Faubion, medical director for The Menopause Society, said in a press release. One significant study from Penn State Hershey Medical Center found that estrogen-based therapies positively impacted cardiovascular health markers. Utilizing data from the Women's Health Initiative for their study, researchers compared cardiovascular health biomarkers in women using estrogen therapies to those on a placebo. "Although we see a few more favorable effects with CEE, both therapies performed well in relation to their impact on biomarkers except for triglycerides. Future research should assess whether other progestogen formulations may be less likely to attenuate estrogen's long-term effect on cholesterol," Dr. Matthew Nudy, lead author, Penn State Hershey Medical Center said.