You’ve likely heard of ginseng and ginkgo biloba—two Chinese herbs long praised for enhancing cognitive function, boosting energy, and reducing stress. But jiaogulan, a lesser-known botanical wonder, is now making waves for its potential to rev up metabolism, lower cholesterol, reduce inflammation, and even promote longevity.Often referred to as the “immortality herb,” jiaogulan (Gynostemma pentaphyllum) grows in the mountainous, forested regions of Asia. It's commonly known as “southern ginseng” or “miracle grass,” thanks to its wide array of health-promoting properties.“Few people in the US know about it,” says Dr. Michael Aziz, a New York City-based, board-certified internist and regenerative medicine expert. Aziz, who consumes 900 milligrams of jiaogulan daily, underscores the growing interest in this plant and breaks down the science behind its rising popularity.Though it has been used for centuries in traditional medicine, jiaogulan’s popularity has spiked in the last decade. Found primarily in herbal teas and dietary supplements, its leaves are valued for their high antioxidant potential.“Jiaogulan tea has a very high ORAC value (a measure of antioxidant capacity). It’s eight times higher than what is found in green tea,” notes Aziz, author of The Ageless Revolution. He recommends brewing one to two teaspoons of dried jiaogulan leaves in 250 milliliters of water. The tea, he says, has a bitter yet slightly sweet taste, though others may describe it as earthy.The bitterness comes from the plant’s saponins, natural compounds believed to contribute significantly to its health effects. “The bitter taste and cold nature of [jiaogulan] are particularly effective in clearing heat and detoxifying the body,” researchers wrote in the Journal of Functional Foods (January edition), highlighting its potential in managing viral hepatitis, chronic bronchitis, and gastroenteritis.In contrast, the herb’s sweet notes are said to nourish the heart and protect the liver, benefiting the flow of qi and blood. It has also shown promise in helping with hyperlipidemia, hypertension, fatty liver, insomnia, and headaches.Jiaogulan contains gypenosides — saponins structurally similar to the ginsenosides in ginseng. These compounds activate AMP-activated protein kinase, a key enzyme that helps maintain energy balance within cells. “They also improve insulin signaling and the function of mitochondria, the energy producers of our cells,” Aziz explains. These cellular improvements may support healthy aging and extend lifespan.Jiaogulan may also exhibit anticancer properties and help lower blood pressure. However, like all supplements, it’s not without potential side effects. While generally safe, some users have reported nausea, diarrhea, dizziness, blurred vision, or even tinnitus. People taking medications — particularly those with diabetes — should consult their doctors before incorporating jiaogulan into their routine. Aziz warns that the herb can significantly lower blood sugar, making dosage adjustments necessary for some.As more people look to traditional herbs for modern health solutions, jiaogulan may be the next big thing in natural wellness.