A surprising rise in unplanned pregnancies among women taking popular weight-loss medications such as Ozempic, Wegovy, and Mounjaro has prompted global health authorities to issue a clear warning0- use effective contraception. The Medicines and Healthcare products Regulatory Agency (MHRA) in the UK has released its first public alert linking the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) with potential contraceptive failure especially among overweight users relying on oral birth control.With more than 40 pregnancy reports associated with these medications such as semaglutide-based injectables (Ozempic and Wegovy), liraglutide (Saxenda and Victoza), and tirzepatide (Mounjaro) the data has raised alarm within the international medical community. The unforeseen side effect is sparking a pressing debate regarding reproductive health, drug safety, and the unforeseen effects of "skinny jabs" that have gained immense popularity.Also Read: CDC Contradicts RFK Jr. On Immunization For Kids Amid COVID Vaccine Changes, Confusion And MisinformationThese drugs in question, such as Ozempic, Wegovy, and Mounjaro, are members of the GLP-1 RA drug class. Initially developed to manage Type 2 diabetes, these medications simulate the GLP-1 hormone to control insulin levels, delay digestion, and curb appetite.Mounjaro, which acts on a second hormone (GIP), extends this mechanism even further by increasing sensitivity to insulin and offering even stronger control over appetite. These actions make the drugs extremely useful as weight losers—but they also modify digestion and hormone balance, potentially disrupting the absorption and metabolism of oral contraceptives, particularly among overweight patients.The MHRA specifically states that Mounjaro can decrease oral contraceptive efficacy, especially in the first four weeks of treatment and following any increase in dosage. This is a major concern for women who use the pill as their method of birth control when on these injections.Also Read: Do You Need More Protein Or Just The Right Kind? Dietician Explains How To Make Smarter ChoicesWhat Is 'Ozempic Baby' Phenomenon?The real-world consequences are starting to become more apparent. Social media groups such as the Facebook group "I Got Pregnant on Ozempic," which had over 750 participants in the past year, are full of anecdotal accounts from women who were surprised to find that they were pregnant after using precautions. "Ozempic babies" these pregnancies are generating new publicity for a once little-discussed side effect of these treatments for weight loss.MHRA records indicate 26 cases of pregnancy associated with Mounjaro, eight with semaglutide (Ozempic and Wegovy), and nine with liraglutide (Saxenda and Victoza). Although not all cases indicated whether the pregnancy was unplanned, at least two did. The trend has health officials and clinicians reassessing how contraception is counselled and controlled in conjunction with these treatments.Contraception, Timing, and Pregnancy RisksThe MHRA and similar medical agencies now fully recommend women taking these weight-loss injections to use safe contraception—ideally combining methods. Women are asked to engage in barrier methods such as condoms alongside oral contraceptives, especially when taking Mounjaro.In addition, these drugs are also contraindicated during pregnancy, conception, or lactation. Since there is no long-term safety information, experts advise that GLP-1 RAs may be having unforeseen effects on fetal development. The MHRA advises women to discontinue using these drugs at least two months prior to trying to conceive so that the drug has been completely cleared from the body.Healthcare providers are also being reminded to clearly convey these warnings at the time of prescribing and to make patients fully aware of the possible reproductive consequences of these potent drugs.The world's popularity with weight-loss injectables is on the rise, fueled partly by endorsement from celebrities, social media buzz, and increasing recognition of obesity as a disease. But that increased usage has far surpassed public awareness of the drugs' side effects—especially those related to reproductive health.Experts caution that off-label use of such drugs, like buying them from beauty salons or internet retailers without prescription, may open more women to unregulated risks. The MHRA insists these drugs are approved to deal with certain clinical conditions and must not be used for cosmetic weight loss only."They are not a weight loss quick fix," the MHRA said. "They have not been evaluated as safe for use for aesthetic purposes, and improper use could have serious health consequences, particularly in pregnancy."Serious Side Effects To Look Out ForBesides reproductive issues, GLP-1 RAs have been associated with a rare but severe complication: acute pancreatitis. The symptoms are chronic stomach pain that radiates to the back and doesn't resolve. Anyone with these symptoms should immediately consult a physician.Prescription leaflets issued with the drugs now contain revised advice on pregnancy, contraception, and possible side effects. Both patients and healthcare professionals are asked to report any adverse effects through the MHRA's Yellow Card scheme, enabling monitoring of the safety of such widely used medicines in real-time.Weight-loss medications such as Ozempic, Wegovy, and Mounjaro are changing lives by providing safe, health-approved solutions to obesity and diabetes. With great benefit, however, comes the burden of informed use. That means for women of childbearing age, it's necessary to know how such medications can affect fertility and the reliability of birth control.If you are taking or thinking about taking GLP-1 medications, discuss with your doctor what kind of birth control is appropriate for you, and if pregnancy is in the cards, get off the drug well ahead of time. While the potential of these drugs is great, their administration has to be based in science, safety, and full medical care—particularly when it comes to reproductive health.