Health and Me

Tanya Dutt

Scientists Identify Antibodies That Can Naturally Prevent Strep A Infections In Children

In a medical advance that may revolutionize the battle against one of the globe's most deadly bacterial infections, researchers have pinpointed individual antibodies that protect children naturally from Strep A. The find not only deconstructs how early childhood immunity is acquired but also paves the way for quicker, more directed development of vaccines — a step that could save as many as half a million lives annually.

Strep A, or <span>Group A Streptococcus</span>, is an extremely prevalent bacterium. At its least severe, it produces sore throats, scarlet fever, and skin infections. But when invasive, it can cause life-threatening disease such as toxic shock syndrome, necrotizing fasciitis (flesh-eating disease), and serious post-infectious disease such as acute rheumatic fever, rheumatic heart disease, and kidney damage.

Worldwide, Strep A infects an estimated 750 million individuals each year and kills over 500,000 — more than influenza, typhoid, or whooping cough. Fatalities are disproportionately found in low- and middle-income nations, where opportunities for timely diagnosis and treatment are poor. In high-income countries, deaths are much less frequent but outbreaks do occur. Late in 2022, a UK and European surge resulted in hundreds of fatalities, many among children.

The World Health Organization has also seen the pressing need for a global, coordinated response to deal with Strep A and its complications. An effective and safe vaccine would be a game-changer, not only avoiding infections but also limiting long-term complications such as rheumatic heart disease.

The most recent breakthrough is from a collaboration of the University of Sheffield, the Medical Research Council (MRC) Unit The Gambia at the London School of Hygiene &amp; Tropical Medicine, and global partners. Scientists monitored the development of natural immunity to Strep A by children over a period in The Gambia.

The research, published in Nature Medicine, found that babies are born with certain maternal antibodies against Strep A. These provide temporary protection but wane rapidly, making children susceptible. Repeated exposure to the bacteria throughout early childhood provokes the immune system to generate its own antibodies — aimed at certain parts of Strep A associated with protection.

"Finding this critical window for building immunity is a finding that has implications for future vaccine approaches," study authors said. By identifying when and how immunity is formed, vaccine developers can create immunization schedules that follow natural defense patterns.

<h2>Finding the Protective Antibodies</h2>

Lead author Dr Alex Keeley, a Wellcome Clinical PhD Fellow in Global Health at the MRC Unit The Gambia and the Florey Institute of Infection at the University of Sheffield, said the research was a game-changer in the fight against Strep A vaccines.

For the first time in humans, we have seen how antibodies that developed following vaccination may prevent infection," said Dr. Keeley. "This knowledge eliminates a significant barrier to vaccine development."

The antibodies found in the research bind directly to proteins on the surface of the Strep A bacterium. By identifying and targeting these proteins, the immune system can inactivate the bacteria before it develops into disease.

For affected communities, the stakes are not just medical but also economic. Gambian researcher and study co-author Fatouamta Camara said the impact of the infection was "devastating" — affecting school enrollment, household income, and health systems.

"A vaccine would bring hope to end this cycle and enable children to flourish," she said.

This finding is one of a larger, multi-institutional effort spearheaded by researchers from the Murdoch Children's Research Institute (MCRI) in Australia, Monash University, University of New South Wales, University of Auckland, and the University of Sheffield. The program also involves significant vaccine makers as members of an advisory board.

Funding from the UK-based Wellcome Trust has enabled researchers to use the world’s only Strep A human challenge model, developed by the MCRI team. This model allows scientists to safely expose healthy adult volunteers to controlled doses of Strep A in order to study immune responses in detail.

Dr. Hannah Frost, from MCRI, said the model is accelerating the vaccine timeline:

"With this investment by Wellcome, we will be responding to some of the largest and most intransigent questions that are blocking the development, licensing, and delivery of an effective <span>Strep A vaccine</span>."

The study enrolled 25 healthy adults in Melbourne who received a low dose of Strep A under close clinical supervision. Blood and saliva samples were collected pre- and post-exposure to assess antibody response.

The results verified that specific antibodies — the same ones found in Gambian children — are associated with immunity against the bacteria. If a vaccine can consistently induce these antibodies, scientists think it could protect individuals through the entire range of Strep A-related illnesses.

<h2>Why This Vaccine Affects Beyond Infection Prevention?</h2>

MCRI Professor Andrew Steer also underlined that an effective vaccine would have implications far greater than protecting against sore throats or skin infections. "Another significant benefit of this vaccine would be decreasing rates of rheumatic heart disease around the world — a disease that can be prevented and has been recognized as a global priority," he said.

Rheumatic heart disease, resulting from untreated or repeated Strep A infections, causes permanent damage to heart valve tissue and is a leading cause of mortality in young adults in most low-resource environments.

Despite being known for decades, vaccine development has trailed behind. The bacterium's complexity, along with the incomplete knowledge of how immunity is acquired, have hindered advancement.

By tracing the development of natural antibodies in children and validating which antibodies offer immunity, researchers now have a definitive target for vaccine design. This could greatly compress the timeline for getting a vaccine to market.

Professor Thushan de Silva, Sheffield's Co-Director of the Florey Institute of Infection, emphasized the value of cross-border collaboration: "This study illustrates the strength of working across institutions to produce high-quality, impactful research in global health."

The second stage of studies will try out various vaccine candidates to determine which one can elicit the same protective antibodies seen in the research. Both high-burden populations such as The Gambia and lower-burden populations such as Australia will have trials, making sure that the vaccine is effective under various populations and conditions.

The target is a single vaccine that will guard against the full spectrum of diseases Strep A can cause — from trivial to fatal.

Despite the obstacles, the convergence of international cooperation, sophisticated lab models, and new insights into immunology brings researchers closer than ever to a solution. Strep A continues to kill hundreds of thousands of people every year, but the finding of naturally protective antibodies in children provides genuine hope. For the first time, scientists now have a definite blueprint to developing a vaccine that might protect the most susceptible — and end one of the world's most enduring infectious threats.

Health Conditions A-Z

health

strep a vaccine

group a streptococcus

strep a antibodies

rheumatic heart disease prevention

strep a immunity

bacterial infection research

strep a global health

Children Are Equally Affected By Both Verbal And Physical Aggression – Does Discipline Need Harsh Punishments And Scoldings?

What Happens To Your Body When You Drink Beer Every Night?

Health News

Superfoods That Support Your Gut Health

Immune-Boosting Foods To Have During Rainy Season

Potato Based Dishes You For Week-Long Meal Prep

Weight Loss Dishes With Fruits You Should Try

Stress Vs. Anxiety: Difference Explained In 60 seconds

Can You Get Heatstroke In Monsoon?

You’re Not Lazy! Women Do Need More Sleep Than Men

How To Ditch Daytime Sleepiness In Office?

Common Mistakes People Make While Eating Flaxseeds

Toddlers In India Are Missing Development Milestones: Study

Yoga Poses You Should Do For Back Pain

Healthy Brunch Ideas For A Lazy Weekend Meal

Balancing Exercises You Should Do For Stability

How Much Can Food Affect Menstruation?

What Should Fitness Look Like For A 13-18 Year Old

Food For Diabetes: What Should A Diabetic Diet Contain

You Don’t Always Need Weights For Strength Training

Feel Sleepy After Lunches - Light And Healthy Office Lunches

Positive Thinking Practice – How Does It Help You?

MIND Diet – Is This A Healthy Diet Or Another Trend?

Yoga Prop Essentials To Improve Your Exercise Session

Should Potatoes Be The Part Of A Healthy Diet?

Best And Worst Foods To Lower Blood Pressure

Low-Impact Cardio Workouts You Should Try

10 Healthy Pasta Salad Dressing For Weight Loss

Breathing Exercise You Should Do To Relieve Stress

Headache vs. Migraine: Difference Explained In 60 Seconds

High Carb Foods That Are Actually Healthy

How Many Times Do You Need To Wash Your Face?

Hypothyroidism Diet – What To Eat And What You Should Avoid

Stretches To Relieve Leg Pain And Numbness After Sitting For Too Long

No-Cook Healthy Meals For Lazy Days At Home

Easy Breakfast Options To Try During Calorie Deficit

How To Stop Muscle Cramps Immediately

Why You Should Go For An Anti-Inflammatory Diet

Foods To Lower Cortisol Levels In Your Body

High-Fiber Dips You Can Make At Home For The Week

Weekend Warrior Exercises To Makeup For Stressful Week

Experiencing Headaches At Word? Natural Remedies To Try

Yoga Poses That Enhance Digestion

In a medical advance that may revolutionize the battle against one of the globe's most deadly bacterial infections, researchers have pinpointed individual antibodies that protect children naturally from Strep A. The find not only deconstructs how early childhood immunity is acquired but also paves the way for quicker, more directed development of vaccines — a step that could save as many as half a million lives annually.Strep A, or Group A Streptococcus, is an extremely prevalent bacterium. At its least severe, it produces sore throats, scarlet fever, and skin infections. But when invasive, it can cause life-threatening disease such as toxic shock syndrome, necrotizing fasciitis (flesh-eating disease), and serious post-infectious disease such as acute rheumatic fever, rheumatic heart disease, and kidney damage.Worldwide, Strep A infects an estimated 750 million individuals each year and kills over 500,000 — more than influenza, typhoid, or whooping cough. Fatalities are disproportionately found in low- and middle-income nations, where opportunities for timely diagnosis and treatment are poor. In high-income countries, deaths are much less frequent but outbreaks do occur. Late in 2022, a UK and European surge resulted in hundreds of fatalities, many among children.The World Health Organization has also seen the pressing need for a global, coordinated response to deal with Strep A and its complications. An effective and safe vaccine would be a game-changer, not only avoiding infections but also limiting long-term complications such as rheumatic heart disease.The most recent breakthrough is from a collaboration of the University of Sheffield, the Medical Research Council (MRC) Unit The Gambia at the London School of Hygiene & Tropical Medicine, and global partners. Scientists monitored the development of natural immunity to Strep A by children over a period in The Gambia.The research, published in Nature Medicine, found that babies are born with certain maternal antibodies against Strep A. These provide temporary protection but wane rapidly, making children susceptible. Repeated exposure to the bacteria throughout early childhood provokes the immune system to generate its own antibodies — aimed at certain parts of Strep A associated with protection."Finding this critical window for building immunity is a finding that has implications for future vaccine approaches," study authors said. By identifying when and how immunity is formed, vaccine developers can create immunization schedules that follow natural defense patterns.Finding the Protective AntibodiesLead author Dr Alex Keeley, a Wellcome Clinical PhD Fellow in Global Health at the MRC Unit The Gambia and the Florey Institute of Infection at the University of Sheffield, said the research was a game-changer in the fight against Strep A vaccines.For the first time in humans, we have seen how antibodies that developed following vaccination may prevent infection," said Dr. Keeley. "This knowledge eliminates a significant barrier to vaccine development."The antibodies found in the research bind directly to proteins on the surface of the Strep A bacterium. By identifying and targeting these proteins, the immune system can inactivate the bacteria before it develops into disease.For affected communities, the stakes are not just medical but also economic. Gambian researcher and study co-author Fatouamta Camara said the impact of the infection was "devastating" — affecting school enrollment, household income, and health systems."A vaccine would bring hope to end this cycle and enable children to flourish," she said.This finding is one of a larger, multi-institutional effort spearheaded by researchers from the Murdoch Children's Research Institute (MCRI) in Australia, Monash University, University of New South Wales, University of Auckland, and the University of Sheffield. The program also involves significant vaccine makers as members of an advisory board.Funding from the UK-based Wellcome Trust has enabled researchers to use the world’s only Strep A human challenge model, developed by the MCRI team. This model allows scientists to safely expose healthy adult volunteers to controlled doses of Strep A in order to study immune responses in detail.Dr. Hannah Frost, from MCRI, said the model is accelerating the vaccine timeline:"With this investment by Wellcome, we will be responding to some of the largest and most intransigent questions that are blocking the development, licensing, and delivery of an effective Strep A vaccine."Testing the Immune BlueprintThe study enrolled 25 healthy adults in Melbourne who received a low dose of Strep A under close clinical supervision. Blood and saliva samples were collected pre- and post-exposure to assess antibody response.The results verified that specific antibodies — the same ones found in Gambian children — are associated with immunity against the bacteria. If a vaccine can consistently induce these antibodies, scientists think it could protect individuals through the entire range of Strep A-related illnesses.Why This Vaccine Affects Beyond Infection Prevention?MCRI Professor Andrew Steer also underlined that an effective vaccine would have implications far greater than protecting against sore throats or skin infections. "Another significant benefit of this vaccine would be decreasing rates of rheumatic heart disease around the world — a disease that can be prevented and has been recognized as a global priority," he said.Rheumatic heart disease, resulting from untreated or repeated Strep A infections, causes permanent damage to heart valve tissue and is a leading cause of mortality in young adults in most low-resource environments.Despite being known for decades, vaccine development has trailed behind. The bacterium's complexity, along with the incomplete knowledge of how immunity is acquired, have hindered advancement.By tracing the development of natural antibodies in children and validating which antibodies offer immunity, researchers now have a definitive target for vaccine design. This could greatly compress the timeline for getting a vaccine to market.Professor Thushan de Silva, Sheffield's Co-Director of the Florey Institute of Infection, emphasized the value of cross-border collaboration: "This study illustrates the strength of working across institutions to produce high-quality, impactful research in global health."The second stage of studies will try out various vaccine candidates to determine which one can elicit the same protective antibodies seen in the research. Both high-burden populations such as The Gambia and lower-burden populations such as Australia will have trials, making sure that the vaccine is effective under various populations and conditions.The target is a single vaccine that will guard against the full spectrum of diseases Strep A can cause — from trivial to fatal.Despite the obstacles, the convergence of international cooperation, sophisticated lab models, and new insights into immunology brings researchers closer than ever to a solution. Strep A continues to kill hundreds of thousands of people every year, but the finding of naturally protective antibodies in children provides genuine hope. For the first time, scientists now have a definite blueprint to developing a vaccine that might protect the most susceptible — and end one of the world's most enduring infectious threats.

scientists identify antibodies that can naturally prevent strep a infections in children

Aarushi Bhadury

First West Nile Virus Case Confirmed In Michigan - What Is West Nile And Who Is At Risk?

Delhi Malaria Cases Increase, Highest Number Of Cases In 5 Years

delhi malaria cases increase, highest number of cases in 5 years

Surge in ‘Stratus’ Covid-19 Cases in the US: CDC Report Says, What Are The Symptoms?

covid-19 summer surge in the us gets worse, cdc says west has the highest levels - are there new symptoms?

US Faces Nationwide STD Epidemic As Cases Surge Past 2.3 Million

us faces nationwide std epidemic as cases surge past 2.3 million

Health & Wellness

What Causes Epilepsy? 5 Common Reasons Why It Happens

what causes epilepsy? 5 common reasons why it happens

The <span>Michigan</span> Department of Health and Human Services has announced the first confirmed human case of <span>West Nile virus</span> (WNV) for 2025. The infected person is a resident of Livingston County, though no other details were released. The first case in 2024 was also found in Livingston County. 

According to Michigan's chief medical executive, Dr. Natasha Bagdasarian, it only takes a single bite from an infected mosquito to cause a severe illness. She advises people to use insect repellent and wear long-sleeved shirts and pants when outside, especially from dusk to dawn, when mosquitoes are most active. 

So far this year, mosquitoes with the virus have also been found in several other counties, including Bay, Kalamazoo, Kent, Macomb, Midland, Saginaw, Tuscola, and Wayne. 

<h2>What Is <span rel="noindex">West Nile</span> Virus? </h2>

The Centers of Disease Control and Prevention (CDC) explains that west Nile virus is the most common disease spread by mosquitoes in the continental United States. It is passed to people through the bite of an infected mosquito. The risk of getting the virus is highest during mosquito season, which typically runs from summer through fall. There is currently no vaccine or specific medicine to treat West Nile virus in humans. 

<h2>What to Expect if You're Infected With West Nile Virus </h2>

Most people who get West Nile virus (about 4 out of 5) will not feel sick at all. About 1 in 5 people will develop what is called West Nile fever, with symptoms that can include:

<ul><li>A fever and headache</li><li>Body aches and joint pain</li><li>Vomiting or diarrhea</li><li>A skin rash</li></ul>

These symptoms usually last a few days to a few weeks, and most people recover on their own. However, a small number of people, about 1 in 150, will get a serious and sometimes deadly illness. This happens when the virus causes inflammation of the brain (encephalitis) or the lining of the brain and spinal cord (meningitis). Symptoms of this more severe illness include: 

<ul><li>A high fever</li><li>A stiff neck</li><li>Confusion or disorientation</li><li>Seizures or paralysis</li><li>A coma</li></ul>

<h2>Who Is at Risk for West Nile Virus? </h2>

Your risk of getting West Nile virus goes up if you are exposed to mosquito bites during the summer. 

While most people who get infected have a mild illness and recover completely, certain people are more likely to get a serious illness from the virus. This includes older people and those with weak immune systems. 

If a healthcare provider thinks you might have West Nile virus, they will likely order a blood test. This test looks for signs in your blood that your body is fighting the virus. In more serious cases, they may also perform a spinal tap (lumbar puncture) to check the fluid around your brain and spinal cord for signs of infection. 

<h2>How Is West Nile Virus Treated? </h2>

There is no specific medicine to cure West Nile virus. Treatment focuses on managing your symptoms and supporting your body while it fights the infection. For the most serious cases, such as West Nile encephalitis or meningitis, a person may need to stay in the hospital for intensive care. This care can include: 

<ul><li>Getting fluids through an IV</li><li>Using a breathing machine (ventilator)</li><li>Receiving care to prevent other infections, like pneumonia</li><li>General nursing care</li></ul>

<h2>How to Protect Yourself from Mosquito Bites </h2>

The CDC explains that since there is no treatment for the virus, the best way to protect yourself is to prevent mosquito bites. You can do this by: 

Look for products that are approved by the Environmental Protection Agency (EPA). The most effective repellents contain ingredients like DEET, picaridin, or oil of lemon eucalyptus. 

Mosquitoes lay their eggs in water, so you should remove any standing water around your home. This includes water in buckets, tires, birdbaths, and flowerpots. 

When you are outside, especially from dusk to dawn when mosquitoes are most active, wear long-sleeved shirts and long pants. 

west nile

michigan

West Nile Virus Case Michigan

West Nile Virus

First human West Nile Virus Case Confirmed

cure for west nile virus

The Michigan Department of Health and Human Services has announced the first confirmed human case of West Nile virus (WNV) for 2025. The infected person is a resident of Livingston County, though no other details were released. The first case in 2024 was also found in Livingston County. According to Michigan's chief medical executive, Dr. Natasha Bagdasarian, it only takes a single bite from an infected mosquito to cause a severe illness. She advises people to use insect repellent and wear long-sleeved shirts and pants when outside, especially from dusk to dawn, when mosquitoes are most active. So far this year, mosquitoes with the virus have also been found in several other counties, including Bay, Kalamazoo, Kent, Macomb, Midland, Saginaw, Tuscola, and Wayne. What Is West Nile Virus? The Centers of Disease Control and Prevention (CDC) explains that west Nile virus is the most common disease spread by mosquitoes in the continental United States. It is passed to people through the bite of an infected mosquito. The risk of getting the virus is highest during mosquito season, which typically runs from summer through fall. There is currently no vaccine or specific medicine to treat West Nile virus in humans. What to Expect if You're Infected With West Nile Virus Most people who get West Nile virus (about 4 out of 5) will not feel sick at all. About 1 in 5 people will develop what is called West Nile fever, with symptoms that can include:A fever and headacheBody aches and joint painVomiting or diarrheaA skin rashThese symptoms usually last a few days to a few weeks, and most people recover on their own. However, a small number of people, about 1 in 150, will get a serious and sometimes deadly illness. This happens when the virus causes inflammation of the brain (encephalitis) or the lining of the brain and spinal cord (meningitis). Symptoms of this more severe illness include: A high feverA stiff neckConfusion or disorientationSeizures or paralysisA comaWho Is at Risk for West Nile Virus? Your risk of getting West Nile virus goes up if you are exposed to mosquito bites during the summer. While most people who get infected have a mild illness and recover completely, certain people are more likely to get a serious illness from the virus. This includes older people and those with weak immune systems. If a healthcare provider thinks you might have West Nile virus, they will likely order a blood test. This test looks for signs in your blood that your body is fighting the virus. In more serious cases, they may also perform a spinal tap (lumbar puncture) to check the fluid around your brain and spinal cord for signs of infection. How Is West Nile Virus Treated? There is no specific medicine to cure West Nile virus. Treatment focuses on managing your symptoms and supporting your body while it fights the infection. For the most serious cases, such as West Nile encephalitis or meningitis, a person may need to stay in the hospital for intensive care. This care can include: Getting fluids through an IVUsing a breathing machine (ventilator)Receiving care to prevent other infections, like pneumoniaGeneral nursing careHow to Protect Yourself from Mosquito Bites The CDC explains that since there is no treatment for the virus, the best way to protect yourself is to prevent mosquito bites. You can do this by: Using bug repellent Look for products that are approved by the Environmental Protection Agency (EPA). The most effective repellents contain ingredients like DEET, picaridin, or oil of lemon eucalyptus. Getting rid of standing water Mosquitoes lay their eggs in water, so you should remove any standing water around your home. This includes water in buckets, tires, birdbaths, and flowerpots. Wearing protective clothingWhen you are outside, especially from dusk to dawn when mosquitoes are most active, wear long-sleeved shirts and long pants. 

First West Nile Virus Case Confirmed In Michigan: How Does The Infection Spread Through The Body?

first west nile virus case confirmed in michigan - what is west nile and who is at risk?

Supriya Ramesh

Study Finds Controlling Inflammation In Diabetics Could Treat Depression, With Approaches Differing

Credis: Canva

Eating These Everyday Nuts Could Help You Lower Your Risk Of Colon Cancer

eating these everyday nuts could help you lower your risk of colon cancer

FDA Approves First Neuroimmune Modulation Device for Rheumatoid Arthritis

fda approves first neuroimmune modulation device for rheumatoid arthritis

Can Obesity Cause Cancer? Study Finds A Link Between This Common Cause Of Obesity In Our Diet And Increased Risk Of Cancer

can obesity cause cancer? study finds a link between this common cause of obesity in our diet and increased risk of cancer

How Fast Is Your Heart Aging? A New Tool Can Find Your Cardiovascular Biological Age

how fast is your heart aging? a new tool can find your cardiovascular biological age

Living with <span>diabetes</span> is already challenging enough, and it comes with <span>depression</span>. Scientists say people with diabetes are up to twice as likely to experience depressive symptoms compared to those without it. But a new study suggests that controlling <span>inflammation</span> in the body could help treat depression in diabetics. However, the best approach depends on the type of diabetes you have.

Type 1 and type 2 diabetes are not the same. The latter is mostly known for the body’s inability to manage blood sugar effectively. In type 1 diabetes, on the other hand, the immune system attacks the insulin-producing cells in the pancreas, leaving the body without its natural blood sugar control.

Researchers have long known that both types can affect <span>mental health</span>. But this new work, published in the journal Diabetologia, suggests that the kind of inflammation happening in your body could hold the key to finding the most effective <span>treatment</span> for depression. 

Diabetes and depression often form a harmful feedback loop. High blood sugar can trigger fatigue and brain fog, depression can lead to poor self-care, and the cycle rolls on. Add inflammation to the mix, a biological response that can affect brain chemistry, and it becomes even harder to break free from the spiral.

The researchers from the Research Institute of the Diabetes Academy Mergentheim (FIDAM) in Germany decided to explore exactly how inflammation affects the success of depression treatments in people with diabetes. They measured 76 different inflammatory markers in the blood of 521 participants with type 1 or type 2 diabetes, all of whom were being monitored for depressive symptoms over a year.

<h3>Behavioural Therapy Works But Not the Same for Everyone</h3>

One of the main treatments tested was <span>cognitive behavioural therapy</span> (CBT), a structured form of psychotherapy that focuses on changing unhelpful thought patterns.

For people with type 2 diabetes and high inflammation levels, CBT worked wonders, reducing symptoms like joylessness and helping patients shift towards more positive thinking.

But for those with type 1 diabetes and similarly high inflammation levels, CBT didn’t have the same magic. Improvements were smaller, especially for symptoms like fatigue, trouble sleeping, or loss of appetite. This suggests that the underlying biology, in this case, the type of inflammation, plays a huge role in determining whether a therapy hits the mark.

The researchers believe it comes down to the nature of the inflammation. In type 2 diabetes, inflammation is largely metabolic, a consequence of the body’s inability to handle blood sugar properly. In type 1 diabetes, the inflammation is autoimmune; the immune system itself is attacking parts of the body.

These two processes likely influence the brain and mood in different ways, which might explain why CBT was a better fit for type 2 diabetics, while type 1 diabetics with high inflammation could benefit more from treatments aimed at reducing inflammation directly, such as anti-inflammatory drugs.

The data revealed an intriguing split. In people with type 2 diabetes, higher levels of 26 <span>biomarkers</span> were linked to bigger improvements in depression symptoms after CBT. In type 1 diabetes, higher levels of 13 biomarkers were actually linked to smaller improvements.

This is more than a curious statistic; it could be the basis for personalised mental health care in diabetes. Instead of trying the same approach for everyone, doctors might one day test inflammation markers first, then choose the right therapy based on each patient’s biological profile.

For diabetics, depression isn’t just an emotional burden; it can directly affect physical health. Low mood can make it harder to stick to a treatment plan, exercise, or eat well. Addressing both conditions at once could lead to better long-term health outcomes.

As study author Norbert Hermanns says, people with type 2 diabetes and high inflammation levels possibly respond particularly well to a change in depressive cognitions through cognitive behavioural therapy. People with type 1 diabetes and high inflammation levels, on the other hand, could benefit more from anti-inflammatory drug therapies.

The right combination of physical and mental health treatments could help patients feel better faster.

<h3>The Future of Tailored Treatments</h3>

The idea of personalised medicine is gaining traction in all areas of healthcare, and this research shows why. In the future, doctors could run a simple blood test, see which inflammatory markers are elevated, and then decide whether a patient might do best with therapy, medication, or both.

inflammation

diabetes

depression

cognitive behavioural therapy

inflammatory drugs

biomarkers

autoimmune disorder

metabolic condition

treatment

mental health

Living with diabetes is already challenging enough, and it comes with depression. Scientists say people with diabetes are up to twice as likely to experience depressive symptoms compared to those without it. But a new study suggests that controlling inflammation in the body could help treat depression in diabetics. However, the best approach depends on the type of diabetes you have.The Two TypesType 1 and type 2 diabetes are not the same. The latter is mostly known for the body’s inability to manage blood sugar effectively. In type 1 diabetes, on the other hand, the immune system attacks the insulin-producing cells in the pancreas, leaving the body without its natural blood sugar control.Researchers have long known that both types can affect mental health. But this new work, published in the journal Diabetologia, suggests that the kind of inflammation happening in your body could hold the key to finding the most effective treatment for depression. Diabetes and depression often form a harmful feedback loop. High blood sugar can trigger fatigue and brain fog, depression can lead to poor self-care, and the cycle rolls on. Add inflammation to the mix, a biological response that can affect brain chemistry, and it becomes even harder to break free from the spiral.The Study The researchers from the Research Institute of the Diabetes Academy Mergentheim (FIDAM) in Germany decided to explore exactly how inflammation affects the success of depression treatments in people with diabetes. They measured 76 different inflammatory markers in the blood of 521 participants with type 1 or type 2 diabetes, all of whom were being monitored for depressive symptoms over a year.Behavioural Therapy Works But Not the Same for EveryoneOne of the main treatments tested was cognitive behavioural therapy (CBT), a structured form of psychotherapy that focuses on changing unhelpful thought patterns.For people with type 2 diabetes and high inflammation levels, CBT worked wonders, reducing symptoms like joylessness and helping patients shift towards more positive thinking.But for those with type 1 diabetes and similarly high inflammation levels, CBT didn’t have the same magic. Improvements were smaller, especially for symptoms like fatigue, trouble sleeping, or loss of appetite. This suggests that the underlying biology, in this case, the type of inflammation, plays a huge role in determining whether a therapy hits the mark.Why the Difference?The researchers believe it comes down to the nature of the inflammation. In type 2 diabetes, inflammation is largely metabolic, a consequence of the body’s inability to handle blood sugar properly. In type 1 diabetes, the inflammation is autoimmune; the immune system itself is attacking parts of the body.These two processes likely influence the brain and mood in different ways, which might explain why CBT was a better fit for type 2 diabetics, while type 1 diabetics with high inflammation could benefit more from treatments aimed at reducing inflammation directly, such as anti-inflammatory drugs.The Numbers Don’t LieThe data revealed an intriguing split. In people with type 2 diabetes, higher levels of 26 biomarkers were linked to bigger improvements in depression symptoms after CBT. In type 1 diabetes, higher levels of 13 biomarkers were actually linked to smaller improvements.This is more than a curious statistic; it could be the basis for personalised mental health care in diabetes. Instead of trying the same approach for everyone, doctors might one day test inflammation markers first, then choose the right therapy based on each patient’s biological profile.Why This MattersFor diabetics, depression isn’t just an emotional burden; it can directly affect physical health. Low mood can make it harder to stick to a treatment plan, exercise, or eat well. Addressing both conditions at once could lead to better long-term health outcomes.As study author Norbert Hermanns says, people with type 2 diabetes and high inflammation levels possibly respond particularly well to a change in depressive cognitions through cognitive behavioural therapy. People with type 1 diabetes and high inflammation levels, on the other hand, could benefit more from anti-inflammatory drug therapies.The right combination of physical and mental health treatments could help patients feel better faster.The Future of Tailored TreatmentsThe idea of personalised medicine is gaining traction in all areas of healthcare, and this research shows why. In the future, doctors could run a simple blood test, see which inflammatory markers are elevated, and then decide whether a patient might do best with therapy, medication, or both.

study finds controlling inflammation in diabetics could treat depression, with approaches differing

With 390+ Unique Genes And Near Cancer Immunity, Scientists Stunned By Species From Chernobyl Radiation

with 390+ unique genes and near cancer immunity, scientists stunned by species from chernobyl radiation

After a day of heavy rain, Delhi is facing a serious health concern, a sharp rise in mosquito-borne illnesses. With waterlogged streets and poor drainage, <span>malaria</span> cases have hit a five-year high. According to the latest data, 135 cases were reported from January 1 to August 2, marking the highest number for this period in the last five years. 

<h2>What Areas In Delhi Are Seeing A Rise In Malaria Cases? </h2>

The city of Delhi is seeing a worrying increase in malaria cases. The West Zone of the city has been hit the hardest, with 30 confirmed cases. This recent data comes from different parts of Delhi, including areas managed by the New Delhi Municipal Council, <span>Delhi Cantt</span>, and Indian Railways. 

As of August 2nd, the number of malaria cases has been growing year after year, with this year’s total of 135 cases being the highest in the last five years for the same period. City officials say this is happening because of a "perfect environment for mosquitoes to breed." They have found that common places where mosquitoes are growing include water-filled coolers, flower pots, drums, and even old tires left on rooftops. 

<h2>Vector-Borne Diseases Also a Concern </h2>

Malaria is a serious, life-threatening disease common in tropical countries. It is spread to people through the bite of certain types of infected mosquitoes. The good news is that malaria is both preventable and curable. Unfortunately, malaria isn't the only mosquito-related problem. Two other diseases carried by mosquitoes are also on the rise: 

<strong>Chikungunya:</strong> So far this year, there have been 20 cases. The West and Central Zones of the city have each reported five cases. This is a noticeable jump from previous years, with a total of 267 cases reported in all of 2024. 

<strong>Dengue: </strong>The city has also seen 291 cases of dengue. The Central Zone has the most cases, with 39. Last year, 11 people sadly died from this disease. 

To fight this problem, health officials have been inspecting homes. They've found that mosquitoes are breeding in over 100,000 houses and have sent out around 76,000 legal notices to residents to clean up these spots. 

<h2>Why Should Malaria Be A Cause Of Concern For People? </h2>

According to IJID Regions journal, Malaria remains a significant health challenge in India, with about 1.3 billion people at risk and over 180,000 cases reported in 2022. The Indian government has been working hard to control and reduce the number of malaria cases. This report looked closely at these efforts and found that several programs have been successful. 

The <span>Urban Malaria Scheme</span>, which focuses on 131 cities, and the Intensified Malaria Control Project, which targets seven high-risk areas, have both been very effective. 

A newer plan, the National Framework for Malaria Elimination, has also helped reduce cases in states like Odisha, which was once a major hotspot for the disease. 

If you think you have malaria, it's essential to get tested right away with a simple blood test. Early treatment can stop a mild case from becoming severe. Doctors will prescribe specific medicines based on the type of malaria and the person's age and health. 

A major challenge in fighting malaria today is that the parasites and mosquitoes are becoming resistant to our medicines and insecticides. Scientists are working on new solutions, like new-generation mosquito nets and updated treatment plans, to combat this resistance and keep the disease under control. 

You can protect yourself from malaria by avoiding mosquito bites and taking special medication, especially if you are traveling to an area where malaria is common. To avoid mosquito bites: 

<ul><li>Use mosquito nets when you sleep</li><li>Wear protective clothing like long sleeves and pants.</li><li>Use mosquito repellent on your skin.</li><li>Install screens on your windows and doors.</li></ul>

malaria

delhi cantt

urban malaria scheme

Delhi Malaria Cases Increase

Delhi Malaria

Malaria Cases and monsoon

Rise In Malaria Number

After a day of heavy rain, Delhi is facing a serious health concern, a sharp rise in mosquito-borne illnesses. With waterlogged streets and poor drainage, malaria cases have hit a five-year high. According to the latest data, 135 cases were reported from January 1 to August 2, marking the highest number for this period in the last five years. What Areas In Delhi Are Seeing A Rise In Malaria Cases? The city of Delhi is seeing a worrying increase in malaria cases. The West Zone of the city has been hit the hardest, with 30 confirmed cases. This recent data comes from different parts of Delhi, including areas managed by the New Delhi Municipal Council, Delhi Cantt, and Indian Railways. As of August 2nd, the number of malaria cases has been growing year after year, with this year’s total of 135 cases being the highest in the last five years for the same period. City officials say this is happening because of a "perfect environment for mosquitoes to breed." They have found that common places where mosquitoes are growing include water-filled coolers, flower pots, drums, and even old tires left on rooftops. Vector-Borne Diseases Also a Concern Malaria is a serious, life-threatening disease common in tropical countries. It is spread to people through the bite of certain types of infected mosquitoes. The good news is that malaria is both preventable and curable. Unfortunately, malaria isn't the only mosquito-related problem. Two other diseases carried by mosquitoes are also on the rise: Chikungunya: So far this year, there have been 20 cases. The West and Central Zones of the city have each reported five cases. This is a noticeable jump from previous years, with a total of 267 cases reported in all of 2024. Dengue: The city has also seen 291 cases of dengue. The Central Zone has the most cases, with 39. Last year, 11 people sadly died from this disease. To fight this problem, health officials have been inspecting homes. They've found that mosquitoes are breeding in over 100,000 houses and have sent out around 76,000 legal notices to residents to clean up these spots. Why Should Malaria Be A Cause Of Concern For People? According to IJID Regions journal, Malaria remains a significant health challenge in India, with about 1.3 billion people at risk and over 180,000 cases reported in 2022. The Indian government has been working hard to control and reduce the number of malaria cases. This report looked closely at these efforts and found that several programs have been successful. The Urban Malaria Scheme, which focuses on 131 cities, and the Intensified Malaria Control Project, which targets seven high-risk areas, have both been very effective. A newer plan, the National Framework for Malaria Elimination, has also helped reduce cases in states like Odisha, which was once a major hotspot for the disease. How to Stay Safe from Malaria?If you think you have malaria, it's essential to get tested right away with a simple blood test. Early treatment can stop a mild case from becoming severe. Doctors will prescribe specific medicines based on the type of malaria and the person's age and health. A major challenge in fighting malaria today is that the parasites and mosquitoes are becoming resistant to our medicines and insecticides. Scientists are working on new solutions, like new-generation mosquito nets and updated treatment plans, to combat this resistance and keep the disease under control. You can protect yourself from malaria by avoiding mosquito bites and taking special medication, especially if you are traveling to an area where malaria is common. To avoid mosquito bites: Use mosquito nets when you sleepWear protective clothing like long sleeves and pants.Use mosquito repellent on your skin.Install screens on your windows and doors.

About Us

Contact Us

Terms & Conditions

Privacy Policy

Company

Health and Me is a premium website with content written and curated to function as a handbook for all Health concerns.

Scientists Identify Antibodies That Can Naturally Prevent Strep A Infections In Children

Quick Stories

First West Nile Virus Case Confirmed In Michigan: How Does The Infection Spread Through The Body?

Study Finds Controlling Inflammation In Diabetics Could Treat Depression, With Approaches Differing

Delhi Malaria Cases Increase, Highest Number Of Cases In 5 Years

Health Conditions A-Z

Children Are Equally Affected By Both Verbal And Physical Aggression – Does Discipline Need Harsh Punishments And Scoldings?

What Happens To Your Body When You Drink Beer Every Night?

Scientists Identify Antibodies That Can Naturally Prevent Strep A Infections In Children