Why do we bloat on a plane? Why do we feel more drunk at 38,000 feet? Why Does Food And Drink Taste So Differently In Air? What makes our faces puffy during flights? Thanks to research, we know the answer to all this. Over the years, scientists have proven that frequent flying in aircraft has a profound impact on health- physical, mental and sexual. Usually, in-cabin air pressure is akin to that witnessed at 5,000 to 8,000 feet. This is equivalent to when you are traversing a mountain or ski resort, where the oxygen deprivation is high. People who change time zones are likely to experience circadian rhythm (our inner clock) misalignment. This leads to a jet lag disorder (JLD), implying insomnia, increased stress, and alterations in hormonal production, regulation, and hormone production.Another factor is humidity inside the aeroplane cabin. The optimal humidity is reported at ground level is around 40-70 per cent. However, humidity levels in aeroplane cabins are around 5-20%. This leads to dehydration and dryness. nose, throat, eyes, etc. This can make infections to spread quickly. Notably, a study by Austrian researchers has shown that a long-distance flight can dry out our skin by up to 37% and may lead to increased itchiness.Beyond our physical bodies, frequent flights also have impact on our brains. Previous research has found that mild hypoxia (low level of oxygen reaching body tissues) can trigger anxiety, depression, negative emotions, panic attacks, claustrophobia along other mental health issues. It can also severely hamper our moods. Frequent flying can also impact your sex life. Several types of research have pointed to a growing link between anxiety, claustrophobia, uncertainty (all witnessed during flights) and libido. Hormones like norepinephrine and epinephrine, lower testosterone levels, which in turn, affects libido and sexual function.Factors associated with air travel can affect your menstrual cycle indirectly. They can lead to cycle irregularities. Experts have repeatedly pointed out that low air pressure leads to changes in estrogen in females and thus, makes their period cycles irregular.