SummaryA sore throat may seem harmless at first, but in rare cases, it can be the warning sign of something far more serious. Caused by the Epstein-Barr virus, 'mono' often mimics a cold but can lead to serious complications, even leading to a ruptured spleen. Doctors now warn that if symptoms like fatigue, swollen glands, and upper abdominal pain accompany a sore throat, it shouldn’t be ignored. Early diagnosis can prevent life-threatening outcomes, even without visible injury.