Health and Me

Ishita Roy

Glioblastoma - The Aggressive Brain Cancer That Has No Cure

Glioblastoma - the aggressive brain cancer that has no cure

Many diseases succumbed to get the attention that they really deserve up until a big name is associated with it. Something similar happened with <span>Glioblastoma</span>, the aggressive brain <span><a href="https://www.healthandme.com/health/cancer">cancer</a></span> that killed former US Rep Mia Love. She was the first Black Republican woman elected to the US House. She died at the age of 49 due to the aggressive brain cancer, which has brought many people's attention on the condition. 

Hailing from Utah, she had undergone treatment for glioblastoma, a malignant brain tumor and received immunotherapy as part of a clinical trial. However, her daughter, earlier this month, revealed that she is no longer responding to the treatment. She passed away at her home in Saratoga Springs, Utah, as per family's statement. 

Love was diagnosed with glioblastoma in 2022, and that is when her doctors had estimated that she only had about 10 to 15 months to survive. However, she had clearly surpassed that. During her speaking engagement in Salt Lake City, she described how she discovered her tumor. She explained that she was on vacation with her friends when she developed she had a bad headache when the plane landed. She went back to the beach and the sun's reflection on the water made her headache unbearable. This is when her husband took her to the hospital and a series of X-rays revealed a tumor in her brain. 

She was taken back to Utah, where, through a surgery, 95% of her tumor was removed. However, biopsy results revealed that it was cancerous and most likely to spread to surrounding brain tissue.

She also entered a clinical trial at Duke University's Preston Robert Tisch Brain Tumor Center in Durham, North Carolina. This involved using her body's immune system to attack the tumor. While initially the tumor shank, it eventually stopped responding to treatments. 

This is called glioblastoma. It is the most aggressive primary brain tumor and there is no cure for it. It keeps mutating no matter whatever is done and can come back. 

A glioblastoma is a fast-growing glioma, a type of tumor that arises from glial cells, which protect nerve cells in the brain and spinal cord.

If no cure, then what can be done? While there exists no known cure to this, there are aggressive treatments such as surgery, radiation, chemotherapy and other targeted therapies which could slow the growth of the tumor. As per experts, even if a surgeon removes all the tumor that can be seen, there are some tumor cells that are still left, which cannot be seen but they multiply quickly. 

As per the MD Anderson Cancer Center, each year, around 12,000 cases are diagnosed in the United States. All glioblastomas are grade IV brain tumors, meaning they contain the most abnormal looking cells and are the most aggressive. About 13,000 Americans are diagnosed with glioblastoma each year, accounting for almost half of all cancerous brain tumors, according to the Cleveland Clinic. More than 10,000 people in the U.S. will succumb to the disease every year, the National Brain Tumor Society reports.

Glioblastoma can occur at any age but is more commonly found in older adults. The average age at diagnosis is 64.

It's the same type of brain cancer that killed former President Joe Biden's son Beau Biden in 2015 and Sen. John McCain in 2018.

What is even more concerning is that researchers have not found a way to prevent glioblastoma and the cause of most of these tumors remain unknown. It is not hereditary, however, the source is unknown. 

Health Conditions A-Z

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brain cancer killed joe biden's son

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beau biden died of brain cancer

what is this aggressive brain cancer

brain cancer without cure

glioblastoma brain cancer with no cure

glioblastoma brain cancer

cancer

cancer survivor

health and wellness

Study Reveals New Models To Help Doctors Distinguish Severe Pneumonia In Children

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Many diseases succumbed to get the attention that they really deserve up until a big name is associated with it. Something similar happened with Glioblastoma, the aggressive brain cancer that killed former US Rep Mia Love. She was the first Black Republican woman elected to the US House. She died at the age of 49 due to the aggressive brain cancer, which has brought many people's attention on the condition. Hailing from Utah, she had undergone treatment for glioblastoma, a malignant brain tumor and received immunotherapy as part of a clinical trial. However, her daughter, earlier this month, revealed that she is no longer responding to the treatment. She passed away at her home in Saratoga Springs, Utah, as per family's statement. What Had Happened To Love?Love was diagnosed with glioblastoma in 2022, and that is when her doctors had estimated that she only had about 10 to 15 months to survive. However, she had clearly surpassed that. During her speaking engagement in Salt Lake City, she described how she discovered her tumor. She explained that she was on vacation with her friends when she developed she had a bad headache when the plane landed. She went back to the beach and the sun's reflection on the water made her headache unbearable. This is when her husband took her to the hospital and a series of X-rays revealed a tumor in her brain. She was taken back to Utah, where, through a surgery, 95% of her tumor was removed. However, biopsy results revealed that it was cancerous and most likely to spread to surrounding brain tissue.She also entered a clinical trial at Duke University's Preston Robert Tisch Brain Tumor Center in Durham, North Carolina. This involved using her body's immune system to attack the tumor. While initially the tumor shank, it eventually stopped responding to treatments. What Is This Disease?This is called glioblastoma. It is the most aggressive primary brain tumor and there is no cure for it. It keeps mutating no matter whatever is done and can come back. A glioblastoma is a fast-growing glioma, a type of tumor that arises from glial cells, which protect nerve cells in the brain and spinal cord.If no cure, then what can be done? While there exists no known cure to this, there are aggressive treatments such as surgery, radiation, chemotherapy and other targeted therapies which could slow the growth of the tumor. As per experts, even if a surgeon removes all the tumor that can be seen, there are some tumor cells that are still left, which cannot be seen but they multiply quickly. Is It Common?As per the MD Anderson Cancer Center, each year, around 12,000 cases are diagnosed in the United States. All glioblastomas are grade IV brain tumors, meaning they contain the most abnormal looking cells and are the most aggressive. About 13,000 Americans are diagnosed with glioblastoma each year, accounting for almost half of all cancerous brain tumors, according to the Cleveland Clinic. More than 10,000 people in the U.S. will succumb to the disease every year, the National Brain Tumor Society reports.Glioblastoma can occur at any age but is more commonly found in older adults. The average age at diagnosis is 64.It's the same type of brain cancer that killed former President Joe Biden's son Beau Biden in 2015 and Sen. John McCain in 2018.What is even more concerning is that researchers have not found a way to prevent glioblastoma and the cause of most of these tumors remain unknown. It is not hereditary, however, the source is unknown. 

glioblastoma - the aggressive brain cancer that has no cure

Aarushi Bhadury

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This Super-Fit Non-Smoker Mom, 34, Diagnosed With Incurable Lung Cancer- Mistook Symptom For Gym Injury

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heart disease symptom that shows up in your legs - survey reveals 46% people don't know of it

Poor Mental Health As Child Limits Capacity To Work In Later Life

poor mental health as child limits capacity to work in later life

<span>Pneumonia</span> is one of the most common infections that was responsible for 14% of all deaths in children under the age of five, influencing the death of 740,180 children in 2019. It is a form of acute respiration infection that affects the lungs, making it difficult or painful to breathe. The Centers of Disease Control and Prevention statistics explain that the number of visits to the emergency department due to pneumonia happens to be 1.4 million people in 2021. 

The symptoms and effects of pneumonia can be mild like coughing, shortness of breath to fever, chest pains nausea, vomiting or diarrhea. However, since the infection can be severe, doctors must treat them with urgency. To help them identify severe cases quicker, a new study published in the Lancet May 2025, reveals new models that can help doctors distinguish severe cases from the moderate ones. 

<h2>Can This Help <span rel="noindex">Lower The Risk Of Pneumonia</span> </h2>

The researchers made an interesting discovery about common cold symptoms. They found that if a child has a runny nose and feels stuffed up, they are actually less likely to have a more serious type of pneumonia. In fact, the chances are lower by quite a bit! On the other hand, the study also pointed out some warning signs that suggest a child might have severe pneumonia. 

The research showed that some common cold symptoms, like a runny nose and congestion, actually means a child is less likely (by 41%) to have a more serious form of pneumonia. On the other hand, certain signs like stomach pain, difficulty breathing, a fast heartbeat, and low oxygen levels in the blood point to a higher chance of <span>severe pneumonia in children</span>. 

The study pointed out that doctors haven't had a good way to know for sure which of these children are in danger of getting much sicker. This new research is trying to fix that problem by giving doctors better tools to quickly identify the kids who need the most help right away. 

<h2>Symptoms That <span rel="noindex">Identified Mild from Severe Pneumonia</span> </h2>

The researchers analyzed 2,200 children between the age bracket of 3 months and 14 years of age. The symptoms that were associated with increased risk of moderate or severe pneumonia 

<ul><li>Children with stomach pain had a significantly higher chance (52%) of having moderate or severe pneumonia.</li><li>Kids who wouldn't drink fluids also faced a greater likelihood (57%) of a more serious pneumonia case.</li><li>If a child had already been given antibiotics before coming to the emergency room, their risk of moderate or severe pneumonia was notably higher (64%).</li><li>Labored breathing made the risk of moderate or severe pneumonia almost three times (2.8 times) as high.</li><li>A faster than normal heartbeat also indicated a considerably increased risk (64%) of more serious pneumonia.</li></ul>

<h2>Pneumonia's Impact on Children's Health </h2>

Pneumonia is not just a minor illness; it's actually one of the most common infections that affects children all across the globe. It's also a very frequent reason why children in the United States end up needing to be admitted to the hospital. This shows just how important it is for doctors and scientists to really understand pneumonia and find the best ways to diagnose it, treat it, and even predict how serious it might become for each child who gets it. 

Researchers pointed out that said that while most kids who get pneumonia will thankfully have a milder form of the illness, there's a small group, about 5 out of every 100 children, who will become very sick and might develop serious health problems. It's absolutely crucial for doctors to be able to spot these children very early on. This way, they can start strong and fast treatments to stop their condition from getting worse and potentially causing long-term issues. 

<h2>Impact of This Study On Pneumonia Care </h2>

Being able to tell how severe a child's pneumonia will be doesn't just help the very sick kids. It can also help the kids who are likely to have a milder illness. If doctors can confidently say that a child's pneumonia is not serious, they can avoid doing extra medical tests that might not be needed. They can also prevent the child from having to stay in the hospital if it's not really necessary, which can be a big relief for both the child and their family.

Severe Pneumonia In Children

Pneumonia

Lower The Risk Of Pneumonia

symptoms of Severe Pneumonia

new model to identify Severe Pneumonia

Identified Mild from Severe Pneumonia

Pneumonia is one of the most common infections that was responsible for 14% of all deaths in children under the age of five, influencing the death of 740,180 children in 2019. It is a form of acute respiration infection that affects the lungs, making it difficult or painful to breathe. The Centers of Disease Control and Prevention statistics explain that the number of visits to the emergency department due to pneumonia happens to be 1.4 million people in 2021. The symptoms and effects of pneumonia can be mild like coughing, shortness of breath to fever, chest pains nausea, vomiting or diarrhea. However, since the infection can be severe, doctors must treat them with urgency. To help them identify severe cases quicker, a new study published in the Lancet May 2025, reveals new models that can help doctors distinguish severe cases from the moderate ones. Can This Help Lower The Risk Of Pneumonia The researchers made an interesting discovery about common cold symptoms. They found that if a child has a runny nose and feels stuffed up, they are actually less likely to have a more serious type of pneumonia. In fact, the chances are lower by quite a bit! On the other hand, the study also pointed out some warning signs that suggest a child might have severe pneumonia. The research showed that some common cold symptoms, like a runny nose and congestion, actually means a child is less likely (by 41%) to have a more serious form of pneumonia. On the other hand, certain signs like stomach pain, difficulty breathing, a fast heartbeat, and low oxygen levels in the blood point to a higher chance of severe pneumonia in children. The study pointed out that doctors haven't had a good way to know for sure which of these children are in danger of getting much sicker. This new research is trying to fix that problem by giving doctors better tools to quickly identify the kids who need the most help right away. Symptoms That Identified Mild from Severe Pneumonia The researchers analyzed 2,200 children between the age bracket of 3 months and 14 years of age. The symptoms that were associated with increased risk of moderate or severe pneumonia Children with stomach pain had a significantly higher chance (52%) of having moderate or severe pneumonia.Kids who wouldn't drink fluids also faced a greater likelihood (57%) of a more serious pneumonia case.If a child had already been given antibiotics before coming to the emergency room, their risk of moderate or severe pneumonia was notably higher (64%).Labored breathing made the risk of moderate or severe pneumonia almost three times (2.8 times) as high.A faster than normal heartbeat also indicated a considerably increased risk (64%) of more serious pneumonia.Pneumonia's Impact on Children's Health Pneumonia is not just a minor illness; it's actually one of the most common infections that affects children all across the globe. It's also a very frequent reason why children in the United States end up needing to be admitted to the hospital. This shows just how important it is for doctors and scientists to really understand pneumonia and find the best ways to diagnose it, treat it, and even predict how serious it might become for each child who gets it. Researchers pointed out that said that while most kids who get pneumonia will thankfully have a milder form of the illness, there's a small group, about 5 out of every 100 children, who will become very sick and might develop serious health problems. It's absolutely crucial for doctors to be able to spot these children very early on. This way, they can start strong and fast treatments to stop their condition from getting worse and potentially causing long-term issues. Impact of This Study On Pneumonia Care Being able to tell how severe a child's pneumonia will be doesn't just help the very sick kids. It can also help the kids who are likely to have a milder illness. If doctors can confidently say that a child's pneumonia is not serious, they can avoid doing extra medical tests that might not be needed. They can also prevent the child from having to stay in the hospital if it's not really necessary, which can be a big relief for both the child and their family.

study reveals new models to help doctors distinguish severe pneumonia in children

Tanya Dutt

About 2 Out Of 5 Heart Failure Patients Don’t See A Cardiologist Even Once A Year

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With the modern medicine, timely access to specialized care often makes the difference between life and death. For patients with <span>heart failure</span>, this reality has never been more true but a troubling new study indicates that roughly 40% of individuals with heart failure do not see a cardiologist even once per year despite strong evidence that even one yearly visit would greatly enhance survival.

Published in the European Heart Journal and delivered at the Heart Failure Congress 2025, the research led by Dr. Guillaume Baudry and Professor Nicolas Girerd from the Clinical Investigation Centre at Nancy University Hospital in France indicates that annual cardiology follow-ups are linked to a 24% lower risk of mortality. The results give rise to immediate questions regarding discrepancies in access to specialist care and how health systems everywhere can improve support for heart failure patients.

Heart failure ensues when the heart becomes incapable of circulating blood, usually a result of ailments like coronary artery disease, hypertension, or past heart attacks. Although irreversible in a majority of instances, heart failure can be treated for many decades with the proper medications, lifestyle modifications, and follow-up visits. Cardiologists have the key role in providing this expert care.

While the previous research took its data from a handful of middle-class medical centers, the new study, based on medical records of 655,919 heart failure patients in France, discovered that almost two in five patients saw no cardiologist whatsoever within a 12-month window. And such minimal contact has dire consequences. In accordance with the scientists, for every 11–16 patients who did visit a cardiologist on at least an annual basis, one life could be saved.

"Ever since we understood the importance of specialist care for cancer, we've also known that heart failure needs specialist attention," said Dr. Baudry. "Our study offers proof that even clinically stable patients can gain benefit from regular care by a cardiologist."

<h2>How Often Should You Visit a Cardiologist?</h2>

To maximize care delivery, the research stratified patients according to two straightforward but strongly predictive factors: recent hospitalization for heart failure and diuretic use (a common set of medications used to counteract fluid accumulation). These factors were used to determine which patients required more frequent follow-ups with specialists.

Patients with no recent hospitalization and no diuretic use were improved by at least one visit a year, cutting their risk of death from 13% to 6.7%.

Those who had not been recently hospitalized but were on diuretics required two to three visits yearly, reducing their risk from 21.3% to 11.9%.

Those hospitalized in the past five years (but not the recent year) also needed two to three visits to reduce risk from 24.8% to 12.9%.

The most at-risk group—those hospitalized in the previous year—benefited most from quarterly visits, lowering death rates from 34.3% to 18.2%.

Importantly, these recommendations are based on existing resource constraints within national healthcare systems, making them practical and scalable globally.

The study also identified significant differences in access to seeing a cardiologist. Women, older patients, and patients with other chronic conditions like diabetes or pulmonary disease were less likely to be referred for cardiology treatment. Indeed, 33.8% of women did not visit a cardiologist in a year, versus 27.9% of men. Women were also less likely to take drugs like RAS inhibitors, which are routine in heart failure treatment.

In spite of these differences, women actually fared better overall in mortality and hospitalization rates—an intriguing and not yet fully explained result that merits further study.

Professor Nicolas Girerd stressed the necessity of systematic reform: "Referral to a cardiologist should be as routine in heart failure as it is in cancer care. Our study demonstrates that two simple markers recent hospitalization and treatment with diuretics—can inform these decisions without the need for expensive diagnostic machinery."

This big, population-based French study is a wake-up call, not only for European healthcare, but for health systems in general. In most nations, primary care doctors are overworked, and patients with complicated diseases such as heart failure might not get the specialist care they require.

In a supporting editorial, Professor Lars Lund of Karolinska Institutet in Stockholm cautioned, "What good is 50 years of discovery and innovation in heart failure treatment if patients aren't accessing that care?" He further said that systemic initiatives are urgently required to include <span>cardiology follow-up</span> in the standard care pathways.

Although this was an observational study and cannot establish direct causality, the scale and robustness of the findings are a powerful argument for change. The researchers plan now to conduct an interventional clinical trial to examine the effect of organized cardiologist follow-up on patient outcomes. They also want to investigate the problem in countries with varying models of healthcare in order to determine world applicability.

<h2>Hidden Cost of Skipping Cardiology Visits</h2>

Heart failure doesn’t always arrive with drama — no sudden collapse, no flashing lights. Instead, it often unfolds quietly, with fatigue, shortness of breath, or swelling easily dismissed as aging or stress. But beneath that silence lies a ticking time bomb. The latest study from France highlights a shocking truth: failing to see a cardiologist even once a year could be a matter of life and death. This isn't about access to the latest technology or expensive tests, it's about presence. 

The absence of a specialist in a patient’s journey with heart failure can mean the absence of life-saving medication adjustments, early warning signs going unnoticed, and critical therapy not being initiated. The data is sobering — skipping that one visit could mean doubling the risk of death.

One of the most powerful insights from the study is its identification of two simple, scalable criteria—recent hospitalization and diuretic use that can predict which heart failure patients are at highest risk. This is revolutionary in its simplicity. It doesn’t require advanced imaging, genomic testing, or expensive algorithms.

heart health

heart failure

cardiologist visit

heart disease treatment

annual cardiac checkup

cardiovascular health

heart failure mortality

cardiology follow-up

With the modern medicine, timely access to specialized care often makes the difference between life and death. For patients with heart failure, this reality has never been more true but a troubling new study indicates that roughly 40% of individuals with heart failure do not see a cardiologist even once per year despite strong evidence that even one yearly visit would greatly enhance survival.Published in the European Heart Journal and delivered at the Heart Failure Congress 2025, the research led by Dr. Guillaume Baudry and Professor Nicolas Girerd from the Clinical Investigation Centre at Nancy University Hospital in France indicates that annual cardiology follow-ups are linked to a 24% lower risk of mortality. The results give rise to immediate questions regarding discrepancies in access to specialist care and how health systems everywhere can improve support for heart failure patients.Heart failure ensues when the heart becomes incapable of circulating blood, usually a result of ailments like coronary artery disease, hypertension, or past heart attacks. Although irreversible in a majority of instances, heart failure can be treated for many decades with the proper medications, lifestyle modifications, and follow-up visits. Cardiologists have the key role in providing this expert care.While the previous research took its data from a handful of middle-class medical centers, the new study, based on medical records of 655,919 heart failure patients in France, discovered that almost two in five patients saw no cardiologist whatsoever within a 12-month window. And such minimal contact has dire consequences. In accordance with the scientists, for every 11–16 patients who did visit a cardiologist on at least an annual basis, one life could be saved."Ever since we understood the importance of specialist care for cancer, we've also known that heart failure needs specialist attention," said Dr. Baudry. "Our study offers proof that even clinically stable patients can gain benefit from regular care by a cardiologist."How Often Should You Visit a Cardiologist?To maximize care delivery, the research stratified patients according to two straightforward but strongly predictive factors: recent hospitalization for heart failure and diuretic use (a common set of medications used to counteract fluid accumulation). These factors were used to determine which patients required more frequent follow-ups with specialists.Patients with no recent hospitalization and no diuretic use were improved by at least one visit a year, cutting their risk of death from 13% to 6.7%.Those who had not been recently hospitalized but were on diuretics required two to three visits yearly, reducing their risk from 21.3% to 11.9%.Those hospitalized in the past five years (but not the recent year) also needed two to three visits to reduce risk from 24.8% to 12.9%.The most at-risk group—those hospitalized in the previous year—benefited most from quarterly visits, lowering death rates from 34.3% to 18.2%.Importantly, these recommendations are based on existing resource constraints within national healthcare systems, making them practical and scalable globally.The study also identified significant differences in access to seeing a cardiologist. Women, older patients, and patients with other chronic conditions like diabetes or pulmonary disease were less likely to be referred for cardiology treatment. Indeed, 33.8% of women did not visit a cardiologist in a year, versus 27.9% of men. Women were also less likely to take drugs like RAS inhibitors, which are routine in heart failure treatment.In spite of these differences, women actually fared better overall in mortality and hospitalization rates—an intriguing and not yet fully explained result that merits further study.Professor Nicolas Girerd stressed the necessity of systematic reform: "Referral to a cardiologist should be as routine in heart failure as it is in cancer care. Our study demonstrates that two simple markers recent hospitalization and treatment with diuretics—can inform these decisions without the need for expensive diagnostic machinery."This big, population-based French study is a wake-up call, not only for European healthcare, but for health systems in general. In most nations, primary care doctors are overworked, and patients with complicated diseases such as heart failure might not get the specialist care they require.In a supporting editorial, Professor Lars Lund of Karolinska Institutet in Stockholm cautioned, "What good is 50 years of discovery and innovation in heart failure treatment if patients aren't accessing that care?" He further said that systemic initiatives are urgently required to include cardiology follow-up in the standard care pathways.Although this was an observational study and cannot establish direct causality, the scale and robustness of the findings are a powerful argument for change. The researchers plan now to conduct an interventional clinical trial to examine the effect of organized cardiologist follow-up on patient outcomes. They also want to investigate the problem in countries with varying models of healthcare in order to determine world applicability.Hidden Cost of Skipping Cardiology VisitsHeart failure doesn’t always arrive with drama — no sudden collapse, no flashing lights. Instead, it often unfolds quietly, with fatigue, shortness of breath, or swelling easily dismissed as aging or stress. But beneath that silence lies a ticking time bomb. The latest study from France highlights a shocking truth: failing to see a cardiologist even once a year could be a matter of life and death. This isn't about access to the latest technology or expensive tests, it's about presence. The absence of a specialist in a patient’s journey with heart failure can mean the absence of life-saving medication adjustments, early warning signs going unnoticed, and critical therapy not being initiated. The data is sobering — skipping that one visit could mean doubling the risk of death.Signs That Could Save LivesOne of the most powerful insights from the study is its identification of two simple, scalable criteria—recent hospitalization and diuretic use that can predict which heart failure patients are at highest risk. This is revolutionary in its simplicity. It doesn’t require advanced imaging, genomic testing, or expensive algorithms.

about 2 out of 5 heart failure patients don’t see a cardiologist even once a year

World's First Human Bladder Transplantation Successful In California

first human bladder transplantation

Biohacker Bryan Johnson Swaps Out His Plasma To Reverse Aging; How Does It Work?

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"i thought it was indigestion" long term pancreatic cancer survivor details her unusual symptoms

In a historic first for modern medicine, surgeons in the United States have successfully performed the world’s first bladder <span>transplant</span> in a living human. Announced on Sunday, the groundbreaking procedure was carried out by a joint team from Keck Medicine of the University of Southern California (USC) and UCLA Health at the Ronald Reagan UCLA Medical Center.

<h4>A Major Leap in Transplant Surgery</h4>

Leading this pioneering operation were Dr. Inderbir Gill, founding executive director of USC Urology, and Dr. Nima Nassiri, director of the UCLA Vascularized Composite Bladder Allograft Transplant Programme. The duo and their multidisciplinary team performed the complex surgery, marking a significant advancement in the treatment of patients with non-functional or severely damaged bladders.

“This surgery marks a historic moment in medicine and could revolutionize the treatment of patients with ‘terminal’ bladders that no longer function,” said Dr. Gill. “Transplantation is already lifesaving for many organs, and now the bladder can join that list.”

The recipient of the transplant was a man who had endured multiple serious health setbacks. More than five years ago, he underwent major cancer surgery that resulted in the loss of most of his bladder. Subsequently, both of his kidneys were removed due to renal cancer, leaving him dialysis-dependent for the past seven years.

“For carefully selected patients, this offers a promising new option,” Dr. Nassiri explained. “This first attempt at bladder transplantation was over four years in the making.”

The innovative procedure involved transplanting both a kidney and a bladder from a deceased donor. Surgeons first implanted the kidney, followed by the bladder. In a final step, they connected the newly transplanted kidney to the new bladder to allow the system to function as a unit. The surgery lasted around eight hours.

<h4>The results were immediate and remarkable.</h4>

“The kidney started producing a large volume of urine right away, and the patient’s kidney function improved immediately,” said Dr. Nassiri. “There was no need for further dialysis, and the urine drained properly into the new bladder.”

Bladder transplants have long been considered a distant possibility due to the organ’s complex structure and function. This successful case could pave the way for new treatment options for people with bladder failure, particularly those whose condition does not respond to conventional therapies.

Despite the complexity of the procedure, the patient is reportedly recovering well and showing positive signs of improvement. The success of this operation could lead to wider adoption in the future and clinical trials for selected patients.

“This is a big step forward,” said Dr. Gill. “We are hopeful that this opens a new chapter in organ transplantation and urological care.”

first human bladder transplant

human bladder transplant

human bladder transplant in California

transplant

In a historic first for modern medicine, surgeons in the United States have successfully performed the world’s first bladder transplant in a living human. Announced on Sunday, the groundbreaking procedure was carried out by a joint team from Keck Medicine of the University of Southern California (USC) and UCLA Health at the Ronald Reagan UCLA Medical Center.A Major Leap in Transplant SurgeryLeading this pioneering operation were Dr. Inderbir Gill, founding executive director of USC Urology, and Dr. Nima Nassiri, director of the UCLA Vascularized Composite Bladder Allograft Transplant Programme. The duo and their multidisciplinary team performed the complex surgery, marking a significant advancement in the treatment of patients with non-functional or severely damaged bladders.“This surgery marks a historic moment in medicine and could revolutionize the treatment of patients with ‘terminal’ bladders that no longer function,” said Dr. Gill. “Transplantation is already lifesaving for many organs, and now the bladder can join that list.”The Patient’s JourneyThe recipient of the transplant was a man who had endured multiple serious health setbacks. More than five years ago, he underwent major cancer surgery that resulted in the loss of most of his bladder. Subsequently, both of his kidneys were removed due to renal cancer, leaving him dialysis-dependent for the past seven years.“For carefully selected patients, this offers a promising new option,” Dr. Nassiri explained. “This first attempt at bladder transplantation was over four years in the making.”How the Surgery Was DoneThe innovative procedure involved transplanting both a kidney and a bladder from a deceased donor. Surgeons first implanted the kidney, followed by the bladder. In a final step, they connected the newly transplanted kidney to the new bladder to allow the system to function as a unit. The surgery lasted around eight hours.The results were immediate and remarkable.“The kidney started producing a large volume of urine right away, and the patient’s kidney function improved immediately,” said Dr. Nassiri. “There was no need for further dialysis, and the urine drained properly into the new bladder.”What This Means for the FutureBladder transplants have long been considered a distant possibility due to the organ’s complex structure and function. This successful case could pave the way for new treatment options for people with bladder failure, particularly those whose condition does not respond to conventional therapies.Despite the complexity of the procedure, the patient is reportedly recovering well and showing positive signs of improvement. The success of this operation could lead to wider adoption in the future and clinical trials for selected patients.“This is a big step forward,” said Dr. Gill. “We are hopeful that this opens a new chapter in organ transplantation and urological care.”

world's first human bladder transplantation successful in california

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