Health and Me

Ishita Roy

A Rare Appendix Cancer Among Millennials And Gen X, Study Reveals

A rare cancer could be prevalent among gen x and millennials

A new study has revealed a sharp rise in cases of a rare <span><a href="https://www.healthandme.com/health/cancer">cancer</a></span>—appendiceal adenocarcinoma—particularly among younger generations. Generation X and millennials are seeing significantly higher rates of this cancer than previous generations, prompting concern among experts.

<h2>What Is Appendiceal Adenocarcinoma?</h2>

Appendiceal adenocarcinoma (AA) is a rare form of cancer that originates in the appendix, a small pouch attached to the large intestine. While appendix cancers are not commonly diagnosed—about 3,000 new cases per year in the U.S.—they appear to be rising at an alarming rate among younger adults.

<h2>Cancer Of Appendix: Generational Surge in Cases</h2>

According to a new paper published in the Annals of Internal Medicine, the rate of AA has tripled among Generation X and quadrupled among millennials compared to those born in the mid-20th century. Researchers at Vanderbilt University Medical Center used data from the U.S. National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) program, which tracked cancer cases from 1975 to 2019.

The numbers are telling: the study found that for people born in 1985, the incidence of appendix cancer is four times higher than for those born in 1945. For individuals born in 1980, it is about three times higher.

Experts say this rise mirrors trends in other gastrointestinal cancers—such as colorectal and stomach cancer—which are also being diagnosed more frequently in adults under 50. Between 1975 and 2019, the researchers recorded 4,858 cases of appendix cancer, with a noticeable uptick in recent decades.

<h2>What Are the Possible Causes of Appendix Cancer?</h2>

Although the exact reasons for this generational increase remain unclear, researchers suggest that lifestyle and environmental factors may be playing a major role. The consumption of ultra-processed foods, sugary beverages, and processed meats has increased sharply in recent decades. Additionally, obesity and metabolic syndrome—both risk factors for various cancers—are more prevalent among younger people today than in past generations.

Lead researcher Dr. Andreana Holowatyji highlighted that the increase in cases is not due to more appendectomies being performed. Surgical removal rates of the appendix have remained largely stable over time, suggesting that other factors, possibly related to diet, lifestyle, and environmental exposure, are contributing to the spike in cases.

<h2>Cancer of Appendix: Challenge of Early Detection</h2>

One of the major hurdles in combating appendiceal adenocarcinoma is the lack of clear early symptoms. Many of the signs—such as bloating, appetite loss, and changes in bowel habits—are vague and can easily be mistaken for more common digestive issues. This often leads to delayed diagnoses and limited treatment options.

With no definitive causes identified, scientists are calling for more research into environmental exposures, genetic factors, and molecular changes that might contribute to the development of appendix cancer. Understanding these elements could help in early detection and potentially lower the rising risk among younger populations.

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A new study has revealed a sharp rise in cases of a rare cancer—appendiceal adenocarcinoma—particularly among younger generations. Generation X and millennials are seeing significantly higher rates of this cancer than previous generations, prompting concern among experts.What Is Appendiceal Adenocarcinoma?Appendiceal adenocarcinoma (AA) is a rare form of cancer that originates in the appendix, a small pouch attached to the large intestine. While appendix cancers are not commonly diagnosed—about 3,000 new cases per year in the U.S.—they appear to be rising at an alarming rate among younger adults.Cancer Of Appendix: Generational Surge in CasesAccording to a new paper published in the Annals of Internal Medicine, the rate of AA has tripled among Generation X and quadrupled among millennials compared to those born in the mid-20th century. Researchers at Vanderbilt University Medical Center used data from the U.S. National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) program, which tracked cancer cases from 1975 to 2019.The numbers are telling: the study found that for people born in 1985, the incidence of appendix cancer is four times higher than for those born in 1945. For individuals born in 1980, it is about three times higher.Experts say this rise mirrors trends in other gastrointestinal cancers—such as colorectal and stomach cancer—which are also being diagnosed more frequently in adults under 50. Between 1975 and 2019, the researchers recorded 4,858 cases of appendix cancer, with a noticeable uptick in recent decades.What Are the Possible Causes of Appendix Cancer?Although the exact reasons for this generational increase remain unclear, researchers suggest that lifestyle and environmental factors may be playing a major role. The consumption of ultra-processed foods, sugary beverages, and processed meats has increased sharply in recent decades. Additionally, obesity and metabolic syndrome—both risk factors for various cancers—are more prevalent among younger people today than in past generations.Lead researcher Dr. Andreana Holowatyji highlighted that the increase in cases is not due to more appendectomies being performed. Surgical removal rates of the appendix have remained largely stable over time, suggesting that other factors, possibly related to diet, lifestyle, and environmental exposure, are contributing to the spike in cases.Cancer of Appendix: Challenge of Early DetectionOne of the major hurdles in combating appendiceal adenocarcinoma is the lack of clear early symptoms. Many of the signs—such as bloating, appetite loss, and changes in bowel habits—are vague and can easily be mistaken for more common digestive issues. This often leads to delayed diagnoses and limited treatment options.With no definitive causes identified, scientists are calling for more research into environmental exposures, genetic factors, and molecular changes that might contribute to the development of appendix cancer. Understanding these elements could help in early detection and potentially lower the rising risk among younger populations.

study reveals a rare appendix cancer among millennials and gen x

Supriya Ramesh

Credits: Canva

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For a country that treats 23 degrees Celsius like it is the Sahara, the UK isn’t exactly built for this kind of heat. While most of us are busy Instagramming sunsets, our bodies might be quietly waving red flags. And that tiredness or weird <span>headache</span> is not just the heat; it could be your system slowly giving signs.

Here is what the heat could actually be doing to you and why you should not ignore it.

You’ve drunk your water, you're not hungover, and yet your head’s pounding like you’ve been at a rock concert. Heat headaches are real, and they’re one of the first signs your body is overheating. So slam a glass of water, sit in front of a fan, and maybe ditch the hot coffee for something icy. It would help if you stuck your feet in a cold bucket like your gran used to do.

At first, you’re drenched like you’ve run a marathon in your own kitchen. But then… nothing. You stop sweating. Your skin feels dry, hot and honestly a bit different. This switch can be dangerous. It’s a classic <span>heatstroke</span> sign. Do not ignore if you’ve been roasting all day and your skin is suddenly dry and flushed; that’s your cue to cool down fast. Think cold compress, wet towel, or even lying in a bath.

Random leg twitches? Sudden tummy cramps while lying down doing absolutely nothing? That’s not just your body being weird; it’s heat cramps. They happen when you’re low on salt and hydration, and they can be surprisingly painful. DIY remedy: Bananas, electrolyte sachets, or if you’re fancy, coconut water. 

Feeling Like You're About to Faint on the Road?

Heat <span>dizziness</span> is uncertain. One minute you’re grabbing grapes; the next you’re gripping the trolley like it’s your last hope. When it’s hot, your blood pressure can drop faster than your motivation on a Monday. If you suddenly feel woozy or like you’re in a bad dream, sit down before you fall down. Always carry a water bottle. 

Can’t Think Straight? Not Just the Heat Making You Dull

If you’re suddenly mixing up names, forgetting simple words, or spacing out mid-text, that could be the heat messing with your brain. Mental fog, confusion, or even irritability are signs that your body is cooking from the inside. If someone is slurring, looking spaced out, or acting like they’ve had a few too many but haven’t, it could be heatstroke. Call for help.

Hot, dry, and suspiciously flushed skin is not the summer glow you think it is. If your skin starts feeling like it belongs in an oven, it means your body’s not coping well with the heat. Especially if your pulse is racing and you feel weirdly calm. Get help. This is your body in SOS mode. Cool off immediately and don’t try to “push through it”.

Heat can make your feet and ankles puff up like inflatable pool toys. It’s not you gaining sudden water weight; it’s literally your blood vessels acting up. So put your feet up, wear comfy shoes, and avoid salty snacks. That means no crisp binge while complaining about the weather.

<ul><li>Hydrate well</li><li>Draw the curtains always</li><li>Sit in front of a fan for relief</li><li>Avoid peak sun hours </li><li>Don’t ignore what your body’s whispering</li></ul>

heatwave

uk weather

dehydration

heatstroke

headache

muscle cramps

dizziness

brain fog

dry skin

swollen feet

For a country that treats 23 degrees Celsius like it is the Sahara, the UK isn’t exactly built for this kind of heat. While most of us are busy Instagramming sunsets, our bodies might be quietly waving red flags. And that tiredness or weird headache is not just the heat; it could be your system slowly giving signs.Here is what the heat could actually be doing to you and why you should not ignore it.That Headache Is a Heat AlarmYou’ve drunk your water, you're not hungover, and yet your head’s pounding like you’ve been at a rock concert. Heat headaches are real, and they’re one of the first signs your body is overheating. So slam a glass of water, sit in front of a fan, and maybe ditch the hot coffee for something icy. It would help if you stuck your feet in a cold bucket like your gran used to do.Sweat, Then No Sweat? That’s TroubleAt first, you’re drenched like you’ve run a marathon in your own kitchen. But then… nothing. You stop sweating. Your skin feels dry, hot and honestly a bit different. This switch can be dangerous. It’s a classic heatstroke sign. Do not ignore if you’ve been roasting all day and your skin is suddenly dry and flushed; that’s your cue to cool down fast. Think cold compress, wet towel, or even lying in a bath.Muscles Twitching on Their Own?Random leg twitches? Sudden tummy cramps while lying down doing absolutely nothing? That’s not just your body being weird; it’s heat cramps. They happen when you’re low on salt and hydration, and they can be surprisingly painful. DIY remedy: Bananas, electrolyte sachets, or if you’re fancy, coconut water. Feeling Like You're About to Faint on the Road?Heat dizziness is uncertain. One minute you’re grabbing grapes; the next you’re gripping the trolley like it’s your last hope. When it’s hot, your blood pressure can drop faster than your motivation on a Monday. If you suddenly feel woozy or like you’re in a bad dream, sit down before you fall down. Always carry a water bottle. Can’t Think Straight? Not Just the Heat Making You DullIf you’re suddenly mixing up names, forgetting simple words, or spacing out mid-text, that could be the heat messing with your brain. Mental fog, confusion, or even irritability are signs that your body is cooking from the inside. If someone is slurring, looking spaced out, or acting like they’ve had a few too many but haven’t, it could be heatstroke. Call for help.Your Skin Feels Like a Radiator?  Hot, dry, and suspiciously flushed skin is not the summer glow you think it is. If your skin starts feeling like it belongs in an oven, it means your body’s not coping well with the heat. Especially if your pulse is racing and you feel weirdly calm. Get help. This is your body in SOS mode. Cool off immediately and don’t try to “push through it”.Swollen Feet?Heat can make your feet and ankles puff up like inflatable pool toys. It’s not you gaining sudden water weight; it’s literally your blood vessels acting up. So put your feet up, wear comfy shoes, and avoid salty snacks. That means no crisp binge while complaining about the weather.Do Not Forget To:Hydrate wellDraw the curtains alwaysSit in front of a fan for reliefAvoid peak sun hours Don’t ignore what your body’s whispering

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Microstress Is Real: These Tiny Terrors Are Quietly Wrecking Your Mental Health

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What is better than being able to ward off one of the most devastating brain diseases? And guess it did not necessarily involve a prescription or a breakthrough drug but simply tweaking your daily habits. That is the message Irish neuroscientist Dr. Sabina Brennan shared when she sat down with Davina McCall on the <span>Begin Again podcast</span>. With <span>dementia</span> cases in the UK soaring and projected to rise, her tips could not come at a better time.

Though the underlying causes of Alzheimer’s, the most common type of dementia, still puzzle experts, Dr. Brennan is certain of one thing: we have more control than we think. Through simple, everyday choices, we can give our brains a fighting chance.

Here is what she says we all should be doing: 

Dr. Brennan insists the real magic lies in movement. “Physical <span>exercise</span> is one of the best things you can do for your <span>brain health</span>,” she told Davina. That is not something most people expect to hear when it comes to dementia, but the link is undeniable.

The secret weapon here is a protein known as brain-derived neurotrophic factor, or BDNF. Think of it as plant food, but for your brain. “I call it ‘Miracle-Gro for the brain’. It makes it easier for you to grow new brain cells and new connections between them. And that is what you want in a healthy brain. Lots of brain cells and connections.”

She goes on to explain why that is so critical in the early stages of dementia. “If you get <span>Alzheimer's disease</span> pathology in your brain in the early stages, it is not about how much pathology, how much disease you have in your brain. It is about how much healthy brain you have to cope with that disease that will allow you to continue functioning for as long as possible.” So build up that mental muscle now, and you may buy yourself more time down the road.

If you needed a reason to chat with your neighbour or call your grandmother, here it is. “A challenging activity for your brain” is how Dr. Brennan describes conversation. “Your brain has to work hard. And that is really, really good.”

She is not talking about small talk alone. It is the deeper connections and dynamic conversations that really get the grey matter going. And crucially, she urges us to be intentional about who we socialise with.

“We tend to hang out with people of the same age as us,” she points out. “But there is no nice way to say it. As you get older, your age cohort will die off. And so people end up socially isolated through no fault of their own.”

Her solution? Build intergenerational friendships before it is too late. “We have to have more intergenerational friendships. And the research shows that everybody benefits in that case; younger people interacting with older people have to do something about that.”

Isolation is not only emotionally draining, she warns; it is mentally damaging too. And visiting older relatives should not be seen as a one-way street. “Visit them as an equal. Do not visit them as someone who is doing a good deed. Talk to them as an intelligent individual.” It is a brain-boosting strategy that doubles as a social fix.

If you have been meaning to learn the ukulele or brush up on French, now is the time. Dr. Brennan’s rallying cry? “Go mental.”

“Learn something new because that is when you harness <span>neuroplasticity</span>,” she says, referring to the brain’s ability to reorganise and adapt. But she admits the word “<span>learning</span>” comes with baggage. “I just wish there was another word for learning because it has got such connotations about education and school and, for a lot of people, a lot of negative [connotations].”

Still, learning, in the broadest sense, is key. She even uses the simple act of opening a door to make her point. “When you open a door for the first time, you are learning how to open that door. Your brain is learning how much pressure to put on that door and how much force you have to push it.”

So, yes, Sudoku is great, but do not stop there. “Once you are good at it and you are comfortable, you have to push yourself to the next level. Go from a simple crossword to a complex crossword. Put a timer on so you do it more quickly. You know, you just have to keep challenging yourself. But it can be anything. If you play a musical instrument, learn another technique.”

Whether it is mastering a new recipe, joining a dance class, or finally tackling those cryptic crosswords, the goal is to keep your brain guessing.

And do not forget rest. Dr. Brennan wraps up her advice with one final reminder: all that mental hard work needs to be processed. “Getting enough sleep so your brain can effectively process and categorise all those new skills is crucial.”

We might not have a cure for Alzheimer’s yet, but according to Dr. Brennan, we are far from powerless. Move your body, keep your social circle diverse, and challenge your mind, not just to stay sharp, but to stay connected and alive. It is simple science with life-changing impact.

mental health

dementia

brain health

exercise

socialising

neuroplasticity

learning

cognitive decline

Alzheimer's Disease

begin again podcast

What is better than being able to ward off one of the most devastating brain diseases? And guess it did not necessarily involve a prescription or a breakthrough drug but simply tweaking your daily habits. That is the message Irish neuroscientist Dr. Sabina Brennan shared when she sat down with Davina McCall on the Begin Again podcast. With dementia cases in the UK soaring and projected to rise, her tips could not come at a better time.Though the underlying causes of Alzheimer’s, the most common type of dementia, still puzzle experts, Dr. Brennan is certain of one thing: we have more control than we think. Through simple, everyday choices, we can give our brains a fighting chance.Here is what she says we all should be doing: 1. Sweat It Out for a Sharper BrainDr. Brennan insists the real magic lies in movement. “Physical exercise is one of the best things you can do for your brain health,” she told Davina. That is not something most people expect to hear when it comes to dementia, but the link is undeniable.The secret weapon here is a protein known as brain-derived neurotrophic factor, or BDNF. Think of it as plant food, but for your brain. “I call it ‘Miracle-Gro for the brain’. It makes it easier for you to grow new brain cells and new connections between them. And that is what you want in a healthy brain. Lots of brain cells and connections.”She goes on to explain why that is so critical in the early stages of dementia. “If you get Alzheimer's disease pathology in your brain in the early stages, it is not about how much pathology, how much disease you have in your brain. It is about how much healthy brain you have to cope with that disease that will allow you to continue functioning for as long as possible.” So build up that mental muscle now, and you may buy yourself more time down the road.2. Socialise More If you needed a reason to chat with your neighbour or call your grandmother, here it is. “A challenging activity for your brain” is how Dr. Brennan describes conversation. “Your brain has to work hard. And that is really, really good.”She is not talking about small talk alone. It is the deeper connections and dynamic conversations that really get the grey matter going. And crucially, she urges us to be intentional about who we socialise with.“We tend to hang out with people of the same age as us,” she points out. “But there is no nice way to say it. As you get older, your age cohort will die off. And so people end up socially isolated through no fault of their own.”Her solution? Build intergenerational friendships before it is too late. “We have to have more intergenerational friendships. And the research shows that everybody benefits in that case; younger people interacting with older people have to do something about that.”Isolation is not only emotionally draining, she warns; it is mentally damaging too. And visiting older relatives should not be seen as a one-way street. “Visit them as an equal. Do not visit them as someone who is doing a good deed. Talk to them as an intelligent individual.” It is a brain-boosting strategy that doubles as a social fix.3. Learn Something NewIf you have been meaning to learn the ukulele or brush up on French, now is the time. Dr. Brennan’s rallying cry? “Go mental.”“Learn something new because that is when you harness neuroplasticity,” she says, referring to the brain’s ability to reorganise and adapt. But she admits the word “learning” comes with baggage. “I just wish there was another word for learning because it has got such connotations about education and school and, for a lot of people, a lot of negative [connotations].”Still, learning, in the broadest sense, is key. She even uses the simple act of opening a door to make her point. “When you open a door for the first time, you are learning how to open that door. Your brain is learning how much pressure to put on that door and how much force you have to push it.”So, yes, Sudoku is great, but do not stop there. “Once you are good at it and you are comfortable, you have to push yourself to the next level. Go from a simple crossword to a complex crossword. Put a timer on so you do it more quickly. You know, you just have to keep challenging yourself. But it can be anything. If you play a musical instrument, learn another technique.”Whether it is mastering a new recipe, joining a dance class, or finally tackling those cryptic crosswords, the goal is to keep your brain guessing.And do not forget rest. Dr. Brennan wraps up her advice with one final reminder: all that mental hard work needs to be processed. “Getting enough sleep so your brain can effectively process and categorise all those new skills is crucial.”We might not have a cure for Alzheimer’s yet, but according to Dr. Brennan, we are far from powerless. Move your body, keep your social circle diverse, and challenge your mind, not just to stay sharp, but to stay connected and alive. It is simple science with life-changing impact.

neuroscientist shares 3 simple lifestyle changes that can delay, or even prevent the onset of alzheimer's

The lazy ones know that <span>facial bleach</span> is one beauty product that comes in handy at any point in time. Whether it was for that last-minute party glow-up or to hide a sudden tan line, facial bleach has long been a last-minute resort in Indian homes. But what really happens when you apply that potent cream on your skin and wait for its effect? We dug in to find out exactly what is going on when your face starts tingling mid-bleach.

Facial bleach usually contains <span>hydrogen peroxide</span> as the main ingredient. This acts as a lightening agent, breaking down <span>melanin</span>, the pigment responsible for skin colour. When you apply bleach, you are not removing hair or tanning; you are just lightening it to make it blend in with your skin. 

When you apply bleach to your skin, it sets off a chain reaction. The hydrogen peroxide oxidises, which in simple terms means it reacts with the pigment and hair proteins, breaking down melanin and making everything lighter in colour. Your facial hair goes blonde, and your skin tone appears brighter, not because it has suddenly become radiant, but because there is less visual contrast.

If you have ever felt your face heat up or sting while bleaching, you have experienced a minor chemical reaction. Bleach is harsh. It strips the skin’s protective barrier ever so slightly, which is why your skin might feel sensitive, look a bit red, or feel tight afterwards. 

Sensitive skin types should deal with it very carefully. Facial bleach can cause <span>inflammation</span>, itchiness, or even mild burns if left on too long or applied too often. And those with active acne, eczema, or any skin condition should steer clear altogether. 

In moderation, bleaching every now and then might not wreak havoc, especially if you are using a reputable brand and following instructions to the dot. But using it too frequently is when trouble begins. Long-term, overuse can cause <span>skin thinning</span>, sensitivity to sunlight, and uneven <span>pigmentation</span>. 

Also, your skin does not get used to bleach. It tolerates it up to a point and then acts up. You might suddenly develop a sensitivity you never had before. 

Bleach has its moment. If you are prepping for a function, want that one-off glow, or just feel like softening the appearance of facial hair, go ahead; just be smart about it. Patch test always. Stick to the recommended time. Do not pile it on like it is moisturiser. And do not expose your skin to the sun immediately. 

Use facial bleach sparingly, respect your skin, and be okay with skipping it altogether if your face is already protesting. Because no glow-up is worth a full-blown skin tantrum. 

facial bleach

hydrogen peroxide

melanin

skin irritation

pigmentation

skin sensitivity

inflammation

skin thinning

beauty routine

Skin & Hair

The lazy ones know that facial bleach is one beauty product that comes in handy at any point in time. Whether it was for that last-minute party glow-up or to hide a sudden tan line, facial bleach has long been a last-minute resort in Indian homes. But what really happens when you apply that potent cream on your skin and wait for its effect? We dug in to find out exactly what is going on when your face starts tingling mid-bleach.What is facial bleach?Facial bleach usually contains hydrogen peroxide as the main ingredient. This acts as a lightening agent, breaking down melanin, the pigment responsible for skin colour. When you apply bleach, you are not removing hair or tanning; you are just lightening it to make it blend in with your skin. What is happening under the surface?When you apply bleach to your skin, it sets off a chain reaction. The hydrogen peroxide oxidises, which in simple terms means it reacts with the pigment and hair proteins, breaking down melanin and making everything lighter in colour. Your facial hair goes blonde, and your skin tone appears brighter, not because it has suddenly become radiant, but because there is less visual contrast.It comes with side effectsIf you have ever felt your face heat up or sting while bleaching, you have experienced a minor chemical reaction. Bleach is harsh. It strips the skin’s protective barrier ever so slightly, which is why your skin might feel sensitive, look a bit red, or feel tight afterwards. Sensitive skin types should deal with it very carefully. Facial bleach can cause inflammation, itchiness, or even mild burns if left on too long or applied too often. And those with active acne, eczema, or any skin condition should steer clear altogether. Can it damage your skin in the long run?In moderation, bleaching every now and then might not wreak havoc, especially if you are using a reputable brand and following instructions to the dot. But using it too frequently is when trouble begins. Long-term, overuse can cause skin thinning, sensitivity to sunlight, and uneven pigmentation. Also, your skin does not get used to bleach. It tolerates it up to a point and then acts up. You might suddenly develop a sensitivity you never had before. Should you bleach at all?Bleach has its moment. If you are prepping for a function, want that one-off glow, or just feel like softening the appearance of facial hair, go ahead; just be smart about it. Patch test always. Stick to the recommended time. Do not pile it on like it is moisturiser. And do not expose your skin to the sun immediately. Use facial bleach sparingly, respect your skin, and be okay with skipping it altogether if your face is already protesting. Because no glow-up is worth a full-blown skin tantrum. 

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A Rare Appendix Cancer Among Millennials And Gen X, Study Reveals

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