Health and Me

Tanya Dutt

Subtle Symptoms May Indicate To Early Warning Signs MS, 15 Years Before You Are Diagnosed

<span>Multiple sclerosis</span> (MS) tends to be viewed as an abrupt disease—vision loss, numbness, tiredness, and other neurological interruptions. But based on a revolutionary new study at the University of British Columbia (UBC), the body could begin to send warning signals as much as 15 years before a diagnosis is officially made.

This study, which appeared in JAMA Network Open, contradicts decades of premises on when MS really gets started. It proposes that the disease can enter an extended and insidious prodromal phase, with such nonspecific symptoms as fatigue, dizziness, headache, depression, and anxiety—often ignored or misdiagnosed. These could all be early whispers of MS in the making.

Led by Dr. Marta Ruiz-Algueró, a postdoctoral fellow at UBC, the study analyzed the medical histories of 2,038 Canadians with MS and compared them to more than 10,000 people without the condition. Using detailed administrative and clinical records that spanned 25 years, researchers tracked how often patients visited healthcare providers before their first classical MS symptoms.

15 years before diagnosis, people who later developed MS were already visiting general practitioners more frequently. Their complaints often centered on fatigue, pain, dizziness, headaches, and mental health concerns like anxiety and depression.

<strong>12 years before: Psychiatrist visits began to rise.</strong>

8 to 9 years before: Visits to neurologists and ophthalmologists increased, often due to vision issues or unexplained nerve-related symptoms.

3 to 5 years before: More visits to emergency medicine and radiology departments.

1 year before diagnosis: Healthcare use spiked across multiple specialties, especially neurology and emergency medicine.

“These patterns suggest that MS has a long and complex prodromal phase where something is happening beneath the surface but hasn’t yet declared itself as MS,” said Dr. Ruiz-Algueró.

<h2>Is Mental Health One of the First Clues?</h2>

One of the most striking revelations was the presence of mental health conditions, particularly anxiety and depression, in the earliest stages of the disease's progression. These symptoms were found to be significantly more common in people who eventually developed MS—often more than a decade before diagnosis.

“We’re only now starting to understand what these early warning signs are, with mental health-related issues appearing to be among the earliest indicators,” added Ruiz-Algueró.

However, the researchers are clear: not everyone with depression or fatigue has MS, and most people with such symptoms will never develop the condition. But in combination with other red flags and patterns, these findings could help doctors detect MS earlier.

<h2>Why These Findings Could Change How MS is Diagnosed?</h2>

Traditionally, MS diagnosis hinges on a demyelinating event, such as vision loss or difficulty walking. But this study shifts the focus further upstream, suggesting that the disease process starts silently, even while symptoms seem unrelated or mild.

Dr. Helen Tremlett, senior author of the study, emphasized that early detection is key:

“By identifying these earlier red flags, we may eventually be able to intervene sooner—whether that’s through monitoring, support, or preventive strategies.”

The implication is profound: if clinicians know what to look for, they could start identifying people at risk much earlier and possibly even slow the progression before major damage occurs.

Multiple sclerosis is an autoimmune condition where the immune system mistakenly attacks the protective covering of nerves—the myelin sheath. Over time, this leads to inflammation, scarring, and disruption in the brain’s ability to communicate with the rest of the body. Common symptoms include:

<ul><li>Chronic fatigue</li><li>Numbness or tingling</li><li>Loss of coordination or balance</li><li>Vision problems</li><li>Muscle weakness</li><li>Memory and cognitive changes</li></ul>

Despite decades of research, the exact cause of MS remains unknown. Genetics, viral infections, environmental factors, and immune system dysfunction are all believed to play roles. Previous studies have also identified MS-specific antibodies in blood up to five years before symptoms, suggesting the immune system may go rogue much earlier than expected.

This extended prodromal phase isn't unique to MS. Parkinson’s disease, for instance, has long been known to begin with subtle mood changes, constipation, and sleep disturbances years before motor symptoms appear.

Tremlett and her team say MS is now showing similar patterns, and it’s time to recognize that the disease doesn’t start with the first lesion—it starts long before that.

“This is the most comprehensive picture to date of how patients engage with a range of healthcare providers in the years leading up to a diagnosis,” said Tremlett. “Our findings dramatically shift the timeline for when these early warning signs are thought to begin.”

While there's still no cure for MS, early detection could pave the way for better disease management, fewer relapses, and slower progression. 

If you're experiencing chronic fatigue, unexplained pain, dizziness, or persistent mental health concerns—and you’re not getting answers—it’s worth advocating for yourself. While these symptoms are common and non-specific, studies like this show they may sometimes be the earliest signs of something more serious, like MS.

Health Conditions A-Z

health

multiple sclerosis

early signs of ms

multiple sclerosis symptoms

ms diagnosis timeline

ms warning signs

neurological disorder signs

fatigue and ms

ms research study

No More BBL For Non-Medics, UK to Regulate High-Risk Beauty Procedures

Oxford Study Reveals 6 Common Health Conditions That Could Lead To Dementia

Health & Wellness

Stress Vs. Anxiety: Difference Explained In 60 seconds

Can You Get Heatstroke In Monsoon?

You’re Not Lazy! Women Do Need More Sleep Than Men

How To Ditch Daytime Sleepiness In Office?

Common Mistakes People Make While Eating Flaxseeds

Toddlers In India Are Missing Development Milestones: Study

Yoga Poses You Should Do For Back Pain

Healthy Brunch Ideas For A Lazy Weekend Meal

Balancing Exercises You Should Do For Stability

How Much Can Food Affect Menstruation?

What Should Fitness Look Like For A 13-18 Year Old

Food For Diabetes: What Should A Diabetic Diet Contain

You Don’t Always Need Weights For Strength Training

Feel Sleepy After Lunches - Light And Healthy Office Lunches

Positive Thinking Practice – How Does It Help You?

MIND Diet – Is This A Healthy Diet Or Another Trend?

Yoga Prop Essentials To Improve Your Exercise Session

Should Potatoes Be The Part Of A Healthy Diet?

Best And Worst Foods To Lower Blood Pressure

Low-Impact Cardio Workouts You Should Try

10 Healthy Pasta Salad Dressing For Weight Loss

Breathing Exercise You Should Do To Relieve Stress

Headache vs. Migraine: Difference Explained In 60 Seconds

High Carb Foods That Are Actually Healthy

How Many Times Do You Need To Wash Your Face?

Hypothyroidism Diet – What To Eat And What You Should Avoid

Stretches To Relieve Leg Pain And Numbness After Sitting For Too Long

No-Cook Healthy Meals For Lazy Days At Home

Easy Breakfast Options To Try During Calorie Deficit

How To Stop Muscle Cramps Immediately

Why You Should Go For An Anti-Inflammatory Diet

Foods To Lower Cortisol Levels In Your Body

High-Fiber Dips You Can Make At Home For The Week

Weekend Warrior Exercises To Makeup For Stressful Week

Experiencing Headaches At Word? Natural Remedies To Try

Yoga Poses That Enhance Digestion

Health Benefits of Walking Backwards

No Eggs? Egg-Alternatives You Can Add To Your Diet

Savory And Smart Ways To Add Broccoli To Your Diet

Calorie Burning Habits That Can Help You Shed Extra Pounds

Multiple sclerosis (MS) tends to be viewed as an abrupt disease—vision loss, numbness, tiredness, and other neurological interruptions. But based on a revolutionary new study at the University of British Columbia (UBC), the body could begin to send warning signals as much as 15 years before a diagnosis is officially made.This study, which appeared in JAMA Network Open, contradicts decades of premises on when MS really gets started. It proposes that the disease can enter an extended and insidious prodromal phase, with such nonspecific symptoms as fatigue, dizziness, headache, depression, and anxiety—often ignored or misdiagnosed. These could all be early whispers of MS in the making.Led by Dr. Marta Ruiz-Algueró, a postdoctoral fellow at UBC, the study analyzed the medical histories of 2,038 Canadians with MS and compared them to more than 10,000 people without the condition. Using detailed administrative and clinical records that spanned 25 years, researchers tracked how often patients visited healthcare providers before their first classical MS symptoms.15 years before diagnosis, people who later developed MS were already visiting general practitioners more frequently. Their complaints often centered on fatigue, pain, dizziness, headaches, and mental health concerns like anxiety and depression.12 years before: Psychiatrist visits began to rise.8 to 9 years before: Visits to neurologists and ophthalmologists increased, often due to vision issues or unexplained nerve-related symptoms.3 to 5 years before: More visits to emergency medicine and radiology departments.1 year before diagnosis: Healthcare use spiked across multiple specialties, especially neurology and emergency medicine.“These patterns suggest that MS has a long and complex prodromal phase where something is happening beneath the surface but hasn’t yet declared itself as MS,” said Dr. Ruiz-Algueró.Is Mental Health One of the First Clues?One of the most striking revelations was the presence of mental health conditions, particularly anxiety and depression, in the earliest stages of the disease's progression. These symptoms were found to be significantly more common in people who eventually developed MS—often more than a decade before diagnosis.“We’re only now starting to understand what these early warning signs are, with mental health-related issues appearing to be among the earliest indicators,” added Ruiz-Algueró.However, the researchers are clear: not everyone with depression or fatigue has MS, and most people with such symptoms will never develop the condition. But in combination with other red flags and patterns, these findings could help doctors detect MS earlier.Why These Findings Could Change How MS is Diagnosed?Traditionally, MS diagnosis hinges on a demyelinating event, such as vision loss or difficulty walking. But this study shifts the focus further upstream, suggesting that the disease process starts silently, even while symptoms seem unrelated or mild.Dr. Helen Tremlett, senior author of the study, emphasized that early detection is key:“By identifying these earlier red flags, we may eventually be able to intervene sooner—whether that’s through monitoring, support, or preventive strategies.”The implication is profound: if clinicians know what to look for, they could start identifying people at risk much earlier and possibly even slow the progression before major damage occurs.How MS Works?Multiple sclerosis is an autoimmune condition where the immune system mistakenly attacks the protective covering of nerves—the myelin sheath. Over time, this leads to inflammation, scarring, and disruption in the brain’s ability to communicate with the rest of the body. Common symptoms include:Chronic fatigueNumbness or tinglingLoss of coordination or balanceVision problemsMuscle weaknessMemory and cognitive changesDespite decades of research, the exact cause of MS remains unknown. Genetics, viral infections, environmental factors, and immune system dysfunction are all believed to play roles. Previous studies have also identified MS-specific antibodies in blood up to five years before symptoms, suggesting the immune system may go rogue much earlier than expected.This extended prodromal phase isn't unique to MS. Parkinson’s disease, for instance, has long been known to begin with subtle mood changes, constipation, and sleep disturbances years before motor symptoms appear.Tremlett and her team say MS is now showing similar patterns, and it’s time to recognize that the disease doesn’t start with the first lesion—it starts long before that.“This is the most comprehensive picture to date of how patients engage with a range of healthcare providers in the years leading up to a diagnosis,” said Tremlett. “Our findings dramatically shift the timeline for when these early warning signs are thought to begin.”While there's still no cure for MS, early detection could pave the way for better disease management, fewer relapses, and slower progression. If you're experiencing chronic fatigue, unexplained pain, dizziness, or persistent mental health concerns—and you’re not getting answers—it’s worth advocating for yourself. While these symptoms are common and non-specific, studies like this show they may sometimes be the earliest signs of something more serious, like MS.

subtle symptoms may indicate to early warning signs ms, 15 years before you are diagnosed

Ishita Roy

Health News

Legionnaire’s Disease Outbreak Kills 2 And Sickens 58 In New York City- Know Symptoms And Risk

legionnaire’s disease outbreak 2 dead and 58 sick in new your city - know symptoms and risk

Nutrition

Fact Check: Is Kratom Supplement A 'Natural' Healer Or An 'Addictive' Danger?

fact check: is kratom supplement a 'natural' healer or an 'addictive' danger?

WHO Reclassifies Hepatitis D As Carcinogenic, Warns Of 2-6% Rise In Liver Cancer Risk

who reclassifies hepatitis d as carcinogenic, warns of 2–6% rise in liver cancer risk

Eli Lilly’s New Weight Loss Pill Helped People With Obesity Shed Nearly 15% In Late-Stage Trials

eli lilly’s new weight loss pill helped people with obesity shed nearly 15% in late-stage trials

The UK government is taking firm action against unsafe and unregulated cosmetic procedures by introducing new legislation aimed at cleaning up what has been described as a “wild west” industry. Health Secretary Wes Streeting has announced that only qualified professionals will be allowed to carry out high-risk aesthetic treatments, including liquid <span>Brazilian butt lifts</span> (BBLs), under new rules expected next year.

<h4>Tighter Rules to Protect Patients</h4>

At present, no license is required to perform procedures like Botox injections or dermal fillers in England. This lack of oversight has led to a rise in botched treatments, some of which have caused permanent scarring, serious health complications, and even death. The government now plans to limit high-risk treatments to qualified healthcare professionals and require providers to be regulated by the Care Quality Commission (CQC).

Lower-risk cosmetic treatments, such as standard Botox and fillers, will also be subject to new licensing rules. Clinics offering these services must register with their local authority, ensuring they meet minimum safety and hygiene standards.

Liquid Brazilian butt lifts involve injecting filler into the buttocks to enhance their shape and size. While marketed as a less invasive alternative to surgical BBLs, the procedure comes with serious risks. These include the possibility of blood clots, infections like sepsis, and in rare cases, death.

In one tragic incident, a 33-year-old woman named Alice Webb died in Gloucestershire last year due to complications linked to a suspected liquid <span>BBL</span> procedure. Cases like hers have raised urgent questions about who is allowed to perform such high-risk treatments.

<h4>Crackdown on Unqualified Providers</h4>

Health officials are also investigating reports that treatments including BBLs, fat injections, and Botox are being offered by unqualified individuals in unregulated settings such as public toilets. The Chartered Trading Standards Institute recently issued a warning about these unsafe practices. Several people reported adverse reactions to Botox-like injections earlier this year, prompting further investigations.

To tackle this, the government is encouraging the public to verify providers’ qualifications and insurance, and to avoid unusually cheap offers that could signal unsafe practices.

The proposed changes will be introduced through amendments to the CQC’s regulations and secondary legislation. In addition to restricting who can offer these treatments, the government also plans to limit access to high-risk cosmetic procedures for under-18s unless they are approved by a qualified healthcare provider. England already made it illegal in 2021 for minors to receive Botox or dermal fillers.

Scotland has also announced similar regulatory plans, while Wales and Northern Ireland have yet to make any moves.

<h4>Support From Experts and Industry Leaders</h4>

Tim Mitchell, president of the Royal College of Surgeons, welcomed the move but called for stronger safeguards. He believes procedures like buttock or breast augmentation should only be carried out by board-recognised cosmetic surgeons. This, he said, would improve standards of care and reduce preventable harm.

Sue Davies of the consumer group Which? warned that these new rules would not be effective unless local enforcement teams, such as trading standards, are given more resources to act against rogue providers.

Millie Kendall, chief executive of the British Beauty Council, said the changes would restore public trust and reduce the number of horror stories associated with the beauty industry.

Health minister Karin Smyth said the government’s actions are aimed at protecting individuals from being exploited by untrained or dishonest practitioners. She emphasized that people will still be free to choose cosmetic treatments, but in a safer and more regulated environment. The goal is to provide peace of mind for consumers while easing the burden on the NHS, which often deals with the consequences of botched procedures.

health and wellness

brazilian butt lifts

BBL license

no more brazilian butt lifts

skincare

skin health

plastic surgery

The UK government is taking firm action against unsafe and unregulated cosmetic procedures by introducing new legislation aimed at cleaning up what has been described as a “wild west” industry. Health Secretary Wes Streeting has announced that only qualified professionals will be allowed to carry out high-risk aesthetic treatments, including liquid Brazilian butt lifts (BBLs), under new rules expected next year.Tighter Rules to Protect PatientsAt present, no license is required to perform procedures like Botox injections or dermal fillers in England. This lack of oversight has led to a rise in botched treatments, some of which have caused permanent scarring, serious health complications, and even death. The government now plans to limit high-risk treatments to qualified healthcare professionals and require providers to be regulated by the Care Quality Commission (CQC).Lower-risk cosmetic treatments, such as standard Botox and fillers, will also be subject to new licensing rules. Clinics offering these services must register with their local authority, ensuring they meet minimum safety and hygiene standards.Why Liquid BBLs Are a ConcernLiquid Brazilian butt lifts involve injecting filler into the buttocks to enhance their shape and size. While marketed as a less invasive alternative to surgical BBLs, the procedure comes with serious risks. These include the possibility of blood clots, infections like sepsis, and in rare cases, death.In one tragic incident, a 33-year-old woman named Alice Webb died in Gloucestershire last year due to complications linked to a suspected liquid BBL procedure. Cases like hers have raised urgent questions about who is allowed to perform such high-risk treatments.Crackdown on Unqualified ProvidersHealth officials are also investigating reports that treatments including BBLs, fat injections, and Botox are being offered by unqualified individuals in unregulated settings such as public toilets. The Chartered Trading Standards Institute recently issued a warning about these unsafe practices. Several people reported adverse reactions to Botox-like injections earlier this year, prompting further investigations.To tackle this, the government is encouraging the public to verify providers’ qualifications and insurance, and to avoid unusually cheap offers that could signal unsafe practices.Planned Legislative ChangesThe proposed changes will be introduced through amendments to the CQC’s regulations and secondary legislation. In addition to restricting who can offer these treatments, the government also plans to limit access to high-risk cosmetic procedures for under-18s unless they are approved by a qualified healthcare provider. England already made it illegal in 2021 for minors to receive Botox or dermal fillers.Scotland has also announced similar regulatory plans, while Wales and Northern Ireland have yet to make any moves.Support From Experts and Industry LeadersTim Mitchell, president of the Royal College of Surgeons, welcomed the move but called for stronger safeguards. He believes procedures like buttock or breast augmentation should only be carried out by board-recognised cosmetic surgeons. This, he said, would improve standards of care and reduce preventable harm.Sue Davies of the consumer group Which? warned that these new rules would not be effective unless local enforcement teams, such as trading standards, are given more resources to act against rogue providers.Millie Kendall, chief executive of the British Beauty Council, said the changes would restore public trust and reduce the number of horror stories associated with the beauty industry.A Step Towards Safer PracticesHealth minister Karin Smyth said the government’s actions are aimed at protecting individuals from being exploited by untrained or dishonest practitioners. She emphasized that people will still be free to choose cosmetic treatments, but in a safer and more regulated environment. The goal is to provide peace of mind for consumers while easing the burden on the NHS, which often deals with the consequences of botched procedures.

no more bbl for non-medics, uk to regulate high-risk beauty procedures

Could Lithium Deficiency In The Brain Trigger Alzheimer’s?

could lithium deficiency in the brain trigger alzheimer’s?

Drinking 'Just' One Diet Soda A Day? You Are 38% Prone To Getting Type 2 Diabetes

drinking 'just' one diet soda a day? you are 38% prone to getting type 2 diabetes

Feel Your Gut Issues Have Increased Since COVID? Science Finally Has Answers

feel your gut issues have increased since covid? science finally has answers

Dementia doesn’t happen overnight. It’s the result of a long chain of biological and lifestyle factors that quietly stack up over decades. A major new study from Oxford University now sheds light on just how early some of these risks can start—and it’s sooner than you might think.

According to the research published in Brain Communications, developing certain health conditions in your 40s and 50s—decades before memory loss begins—can sharply raise your chances of developing dementia later in life. Specifically, heart disease, atrial fibrillation, diabetes, anxiety, depression, and stroke were all linked to a significantly increased risk. And it’s not just having one condition that matters—multiple illnesses over time (a phenomenon called multimorbidity) appears to compound the risk dramatically.

Researchers at the University of Oxford analyzed data from more than 280,000 participants in the UK Biobank, focusing on the timing and combination of 46 chronic illnesses. They found that up to 80% of dementia patients had two or more health conditions leading up to their diagnosis. But more critically, the age at which these conditions first appeared had a major influence on dementia risk.

<strong>Before age 55: Heart disease, atrial fibrillation, and diabetes had the strongest connection to later dementia.</strong>

Between ages 55 and 70: Stroke, anxiety, and depression doubled the risk.

These findings don’t just point to correlation—they suggest there are “critical time windows” when certain illnesses may do the most damage to long-term cognitive health.

Dr. Sana Suri, associate professor and senior fellow at Oxford Brain Sciences, emphasized the importance of identifying not just which conditions matter, but when they matter most: “This study has identified how specific illnesses tend to co-exist with each other, and also the critical time windows in which they could pose the greatest risk.”

<h2>Conditions That Could Set the Stage for Dementia</h2>

Cardiovascular issues—especially those that start before age 55—appear to set the stage for dementia decades later. Poor heart health means reduced blood flow to the brain, which can lead to structural changes, shrinkage, and even microinfarcts (tiny strokes). Over time, this damages the brain's ability to process and retain information.

Studies have long linked hypertension and atherosclerosis to cognitive decline. But this study reinforces the idea that early-onset heart disease isn't just a heart issue—it's a brain issue too.

AFib, a common heart rhythm disorder, was strongly associated with increased dementia risk—particularly when diagnosed early in life. It may contribute to the formation of blood clots, which can travel to the brain and cause strokes, even small ones that go undetected.

AFib also leads to inefficient blood circulation, which deprives brain cells of oxygen over time, potentially accelerating cognitive decline.

Type 2 diabetes damages blood vessels throughout the body—including the brain. It also increases inflammation and oxidative stress, both of which are implicated in dementia. Chronically high blood sugar levels can impair memory, learning, and executive function over the years.

The Oxford study suggests that diabetes diagnosed before midlife (age 55) is especially dangerous for long-term brain health. Managing blood sugar early could be a powerful intervention strategy.

Anxiety isn’t just an emotional state—it also has biological consequences. Chronic anxiety floods the body with stress hormones like cortisol, which, over time, can damage the hippocampus (the area of the brain responsible for memory formation).

The study showed that anxiety diagnosed between ages 55 and 70 had a strong link to future dementia, potentially due to cumulative stress or co-existing health problems like insomnia or cardiovascular disease.

Like anxiety, depression can cause neurobiological changes in the brain, including reduced brain volume in key areas like the prefrontal cortex and hippocampus. It also disrupts sleep, appetite, and motivation—factors that are all linked to cognitive decline when persistent.

Importantly, depression may not just be an early symptom of dementia, as once believed—it may actually play a causal role in increasing risk, particularly if it arises in midlife.

Stroke was one of the most powerful predictors of dementia risk identified in the study. Whether large or small, strokes damage brain tissue, disrupt communication between brain regions, and increase the likelihood of future vascular events.

When strokes occur between ages 55 and 70, the risk of dementia appears to double. Preventing stroke through better blood pressure control, physical activity, and managing cholesterol could play a major role in reducing dementia burden globally.

<h2>How Lifestyle Habits Increase Risk Of Dementia?</h2>

While these conditions pose serious risks, they’re often tied to modifiable behaviors. That’s why lifestyle matters just as much as biology when it comes to preventing dementia.

<ul><li>Poor sleep, especially in midlife, is now linked to structural brain changes.</li><li>Chronic stress and high cortisol levels are known to impair memory and shrink the brain.</li><li>Excess alcohol, particularly over many years, can lead to alcohol-related brain damage (ARBD).</li><li>Ultra-processed foods, low in fiber and high in sugar, are associated with increased inflammation and dementia risk.</li><li>Lack of physical activity contributes to vascular damage, insulin resistance, and reduced brain resilience.</li><li>Social isolation has been shown to speed cognitive decline—engagement and social interaction are critical to brain longevity.</li></ul>

<h2>Is Dementia Prevention Possible?</h2>

This study changes the way we think about dementia prevention. It’s not something to start worrying about at 70. It’s something to pay attention to in your 40s, 50s, and 60s—especially if you’re already living with chronic health issues.

Dr. Suri stresses that prevention needs to be dynamic and age-sensitive: “Future studies could examine whether efforts to manage or prevent cardiovascular problems in early-to-midlife, followed by <span>mental health</span> and neurological disorders when people are in their 50s and 60s, might reduce the risk of dementia.”

In other words- the earlier, the better. But it’s never too late to change course. Dementia isn’t inevitable. While you can’t change your genes or erase your age, you can manage the conditions that may tip the scales toward cognitive decline. This study is a wake-up call to healthcare providers and patients alike—start the conversation early, monitor chronic illnesses proactively, and don’t underestimate the power of midlife choices.

If heart disease, diabetes, stroke, anxiety, or depression are part of your story, now’s the time to treat not just the symptoms—but the long-term risk that may be quietly building.

mental health

dementia risk factors

dementia and health conditions

early signs of dementia

dementia prevention tips

dementia and depression

diabetes and dementia

oxford dementia study

Dementia doesn’t happen overnight. It’s the result of a long chain of biological and lifestyle factors that quietly stack up over decades. A major new study from Oxford University now sheds light on just how early some of these risks can start—and it’s sooner than you might think.According to the research published in Brain Communications, developing certain health conditions in your 40s and 50s—decades before memory loss begins—can sharply raise your chances of developing dementia later in life. Specifically, heart disease, atrial fibrillation, diabetes, anxiety, depression, and stroke were all linked to a significantly increased risk. And it’s not just having one condition that matters—multiple illnesses over time (a phenomenon called multimorbidity) appears to compound the risk dramatically.Researchers at the University of Oxford analyzed data from more than 280,000 participants in the UK Biobank, focusing on the timing and combination of 46 chronic illnesses. They found that up to 80% of dementia patients had two or more health conditions leading up to their diagnosis. But more critically, the age at which these conditions first appeared had a major influence on dementia risk.Before age 55: Heart disease, atrial fibrillation, and diabetes had the strongest connection to later dementia.Between ages 55 and 70: Stroke, anxiety, and depression doubled the risk.These findings don’t just point to correlation—they suggest there are “critical time windows” when certain illnesses may do the most damage to long-term cognitive health.Dr. Sana Suri, associate professor and senior fellow at Oxford Brain Sciences, emphasized the importance of identifying not just which conditions matter, but when they matter most: “This study has identified how specific illnesses tend to co-exist with each other, and also the critical time windows in which they could pose the greatest risk.”Conditions That Could Set the Stage for Dementia1. Heart DiseaseCardiovascular issues—especially those that start before age 55—appear to set the stage for dementia decades later. Poor heart health means reduced blood flow to the brain, which can lead to structural changes, shrinkage, and even microinfarcts (tiny strokes). Over time, this damages the brain's ability to process and retain information.Studies have long linked hypertension and atherosclerosis to cognitive decline. But this study reinforces the idea that early-onset heart disease isn't just a heart issue—it's a brain issue too.2. Atrial Fibrillation (AFib)AFib, a common heart rhythm disorder, was strongly associated with increased dementia risk—particularly when diagnosed early in life. It may contribute to the formation of blood clots, which can travel to the brain and cause strokes, even small ones that go undetected.AFib also leads to inefficient blood circulation, which deprives brain cells of oxygen over time, potentially accelerating cognitive decline.3. DiabetesType 2 diabetes damages blood vessels throughout the body—including the brain. It also increases inflammation and oxidative stress, both of which are implicated in dementia. Chronically high blood sugar levels can impair memory, learning, and executive function over the years.The Oxford study suggests that diabetes diagnosed before midlife (age 55) is especially dangerous for long-term brain health. Managing blood sugar early could be a powerful intervention strategy.4. AnxietyAnxiety isn’t just an emotional state—it also has biological consequences. Chronic anxiety floods the body with stress hormones like cortisol, which, over time, can damage the hippocampus (the area of the brain responsible for memory formation).The study showed that anxiety diagnosed between ages 55 and 70 had a strong link to future dementia, potentially due to cumulative stress or co-existing health problems like insomnia or cardiovascular disease.5. DepressionLike anxiety, depression can cause neurobiological changes in the brain, including reduced brain volume in key areas like the prefrontal cortex and hippocampus. It also disrupts sleep, appetite, and motivation—factors that are all linked to cognitive decline when persistent.Importantly, depression may not just be an early symptom of dementia, as once believed—it may actually play a causal role in increasing risk, particularly if it arises in midlife.6. StrokeStroke was one of the most powerful predictors of dementia risk identified in the study. Whether large or small, strokes damage brain tissue, disrupt communication between brain regions, and increase the likelihood of future vascular events.When strokes occur between ages 55 and 70, the risk of dementia appears to double. Preventing stroke through better blood pressure control, physical activity, and managing cholesterol could play a major role in reducing dementia burden globally.How Lifestyle Habits Increase Risk Of Dementia?While these conditions pose serious risks, they’re often tied to modifiable behaviors. That’s why lifestyle matters just as much as biology when it comes to preventing dementia.Poor sleep, especially in midlife, is now linked to structural brain changes.Chronic stress and high cortisol levels are known to impair memory and shrink the brain.Excess alcohol, particularly over many years, can lead to alcohol-related brain damage (ARBD).Ultra-processed foods, low in fiber and high in sugar, are associated with increased inflammation and dementia risk.Lack of physical activity contributes to vascular damage, insulin resistance, and reduced brain resilience.Social isolation has been shown to speed cognitive decline—engagement and social interaction are critical to brain longevity.Is Dementia Prevention Possible?This study changes the way we think about dementia prevention. It’s not something to start worrying about at 70. It’s something to pay attention to in your 40s, 50s, and 60s—especially if you’re already living with chronic health issues.Dr. Suri stresses that prevention needs to be dynamic and age-sensitive: “Future studies could examine whether efforts to manage or prevent cardiovascular problems in early-to-midlife, followed by mental health and neurological disorders when people are in their 50s and 60s, might reduce the risk of dementia.”In other words- the earlier, the better. But it’s never too late to change course. Dementia isn’t inevitable. While you can’t change your genes or erase your age, you can manage the conditions that may tip the scales toward cognitive decline. This study is a wake-up call to healthcare providers and patients alike—start the conversation early, monitor chronic illnesses proactively, and don’t underestimate the power of midlife choices.If heart disease, diabetes, stroke, anxiety, or depression are part of your story, now’s the time to treat not just the symptoms—but the long-term risk that may be quietly building.

oxford study reveals 6 common health conditions that could lead to dementia

Supriya Ramesh

How Much Time Does It Take To Recover From A Hair Transplant? A Week-By-Week Reality Check

Credits: Canva

‘Lucky To Be Alive', US Woman Wakes Up From A Coma Just Seconds Before Doctors Begin Organ Harvesting

‘lucky to be alive', us woman wakes up from a coma just seconds before doctors begin organ harvesting

How To Tell Your Skin Barrier Is Damaged? Step-By-Step Guide To Rebuilding Your Skin’s Defenses

how to tell your skin barrier is damaged? step-by-step guide to rebuilding your skin’s defenses

Fit And Healthy Flight Attendant Got A Life-Changing Diagnosis After He Noticed A Persistent Cough

fit and healthy flight attendant got a life-changing diagnosis after he noticed a persistent cough

Fitness

What Happens To Your Body When You Do HIIT Workout Daily?

what happens to your body when you do hiit workout daily?

A <span>hair transplant</span> is a surgical procedure, and like any medical intervention, it comes with a recovery period. While the healing of the scalp typically takes one to two weeks, visible results in terms of <span>hair growth</span> take much longer. It can take up to 12 months for the full results to show, depending on individual healing patterns, the technique used, and how well post-procedure care is followed.

Hair does not magically grow overnight. Recovery is a journey that requires a bit of patience and some TLC. 

<strong>Here is what really happens post-transplant, week by week.</strong>

<h3>First 24-72 Hours</h3>Immediately after the procedure, your scalp will look like it has been through something... because it has. Tiny <span>scabs</span> form around each transplanted hair follicle, and some redness or swelling might make your head resemble a tomato. This is totally normal. Your job for the next couple of days is to leave it alone. No scratching, no scrubbing, and absolutely no washing unless your doctor says so. You will likely be given a saline spray and some instructions. Also, avoid any strenuous activity. 

<h3>Week 1: The “Don’t Touch My Head” Era</h3>By the end of the first week, the swelling and redness begin to settle. The scabs may start flaking off, which is a good sign that healing is underway.

You will be allowed to gently wash your hair by now, using a special <span>shampoo</span>. 

<h3>Week 2: Shedding Starts</h3>Just when you think things are improving, the so-called “shock loss” kicks in. This is where the newly transplanted hairs decide to bail. Yes, they fall out. But it is all part of the process. The <span>follicles</span> are still intact under your skin, but the hair above the surface drops. 

<h3>Week 3 to 4: Back to Square One </h3>By this point, your scalp should be looking fairly normal again. No scabs, no redness. This is the quiet phase. Nothing much happens on the surface, but deep down, your follicles are prepping. You can resume your usual <span>haircare routine</span>, avoiding the harsh treatments and even a gym session or two if approved.

<h3>Month 2 to 3: It Can Get Itchy </h3>You might start feeling a bit of tingling or <span>itching</span>. That is often a good sign. It means the follicles are waking up and beginning to grow new strands. However, do not expect full-on hair just yet. You might notice patchy, fine hairs sprouting here and there, but nothing glamorous. Still, it is enough to get your hopes up and start stalking your own scalp in the mirror every day.

<h3>Month 4 to 6: Hair, Finally!</h3>This is when the magic really begins. The new hairs begin to grow in earnest. They may be thin and wispy at first, like baby hair, but they will gradually thicken with time. You will also notice your <span>hairline</span> shaping up. The growth is uneven for a while, so do not expect red carpet-ready hair just yet.

<h3>Month 7 to 12: Full Bloom Season</h3>By now, up to 70-80 per cent of your transplanted hair will have grown in. The strands get thicker, stronger, and more natural-looking. You can cut, style, and show off your new hair without people guessing you had a procedure. It is also the time when people start asking what shampoo you are using or what actually brought your hairline back from the brink.

Recovery time after a hair transplant is not just about healing; it is about growth. Physically, you will be fine after a week or two. But to see visible, satisfying results, expect the full process to stretch over 9 to 12 months.

hair transplant

scabs

shock loss

hair growth

follicles

itching

hairline

Skin & Hair

haircare routine

shampoo

A hair transplant is a surgical procedure, and like any medical intervention, it comes with a recovery period. While the healing of the scalp typically takes one to two weeks, visible results in terms of hair growth take much longer. It can take up to 12 months for the full results to show, depending on individual healing patterns, the technique used, and how well post-procedure care is followed.Hair does not magically grow overnight. Recovery is a journey that requires a bit of patience and some TLC. Here is what really happens post-transplant, week by week.First 24-72 HoursImmediately after the procedure, your scalp will look like it has been through something... because it has. Tiny scabs form around each transplanted hair follicle, and some redness or swelling might make your head resemble a tomato. This is totally normal. Your job for the next couple of days is to leave it alone. No scratching, no scrubbing, and absolutely no washing unless your doctor says so. You will likely be given a saline spray and some instructions. Also, avoid any strenuous activity. Week 1: The “Don’t Touch My Head” EraBy the end of the first week, the swelling and redness begin to settle. The scabs may start flaking off, which is a good sign that healing is underway.You will be allowed to gently wash your hair by now, using a special shampoo. Week 2: Shedding StartsJust when you think things are improving, the so-called “shock loss” kicks in. This is where the newly transplanted hairs decide to bail. Yes, they fall out. But it is all part of the process. The follicles are still intact under your skin, but the hair above the surface drops. Week 3 to 4: Back to Square One By this point, your scalp should be looking fairly normal again. No scabs, no redness. This is the quiet phase. Nothing much happens on the surface, but deep down, your follicles are prepping. You can resume your usual haircare routine, avoiding the harsh treatments and even a gym session or two if approved.Month 2 to 3: It Can Get Itchy You might start feeling a bit of tingling or itching. That is often a good sign. It means the follicles are waking up and beginning to grow new strands. However, do not expect full-on hair just yet. You might notice patchy, fine hairs sprouting here and there, but nothing glamorous. Still, it is enough to get your hopes up and start stalking your own scalp in the mirror every day.Month 4 to 6: Hair, Finally!This is when the magic really begins. The new hairs begin to grow in earnest. They may be thin and wispy at first, like baby hair, but they will gradually thicken with time. You will also notice your hairline shaping up. The growth is uneven for a while, so do not expect red carpet-ready hair just yet.Month 7 to 12: Full Bloom SeasonBy now, up to 70-80 per cent of your transplanted hair will have grown in. The strands get thicker, stronger, and more natural-looking. You can cut, style, and show off your new hair without people guessing you had a procedure. It is also the time when people start asking what shampoo you are using or what actually brought your hairline back from the brink.Recovery time after a hair transplant is not just about healing; it is about growth. Physically, you will be fine after a week or two. But to see visible, satisfying results, expect the full process to stretch over 9 to 12 months.

how much time does it take to recover from a hair transplant? a week-by-week reality check

About Us

Company

Health and Me is a premium website with content written and curated to function as a handbook for all Health concerns.

Subtle Symptoms May Indicate To Early Warning Signs MS, 15 Years Before You Are Diagnosed

Quick Stories

No More BBL For Non-Medics, UK to Regulate High-Risk Beauty Procedures

Oxford Study Reveals 6 Common Health Conditions That Could Lead To Dementia

How Much Time Does It Take To Recover From A Hair Transplant? A Week-By-Week Reality Check

Health Conditions A-Z

No More BBL For Non-Medics, UK to Regulate High-Risk Beauty Procedures

Subtle Symptoms May Indicate To Early Warning Signs MS, 15 Years Before You Are Diagnosed

Oxford Study Reveals 6 Common Health Conditions That Could Lead To Dementia