The human papillomavirus (HPV) is the most common viral infection worldwide, with more than 200 known types. While some types lead to benign skin warts, others are responsible for severe health threats, such as cervical, throat, anal, and penile cancers. The HPV vaccine provides strong protection against the most lethal strains, avoiding long-term health complications.For adults, teenagers, and parents, being informed about the role of HPV vaccination is important in making an educated healthcare choice. Should teens get vaccinated? Can adults benefit from it? Does it affect puberty or hormonal balance? In this detailed guide, we break down everything you need to know about the HPV vaccine, its benefits, and why it’s a crucial step in cancer prevention.We asked Senior Consultant in Gynae Oncology and Robotic Surgery Dr. Monika Meena, all important questions related to HPV for teens, adults, and parents. Let's understand the importance and relevance of the vaccination.How the HPV Vaccine Works?The HPV vaccine is intended to educate the immune system to detect and fight high-risk HPV types before they cause harm. It is not a cure for an infection that already exists, but rather prevents future infections from occurring. The HPV vaccine helps the immune system recognize and fight off high-risk strains of the virus before they cause harm. It protects against:Genital wartsCervical cancerVaginal, vulvar, anal, and penile cancersMouth, throat, head, and neck cancers linked to HPVWhile the vaccine cannot treat existing HPV infections, it can prevent new infections from occurring, making early vaccination particularly effective. By getting the HPV vaccine, people develop immunity to the virus, lowering their risk of getting HPV-related cancers and genital warts. The vaccine works best in people who have not yet been exposed to HPV, which is why it is mostly given to preteens before they become sexually active.Who Should Get the HPV Vaccine?Children and TeensPreteen dosing is recommended by top health agencies, such as the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), for boys and girls to get the HPV vaccine at ages 9 through 15. The preteen is when the vaccine is most effective since it has the highest immune response in preteens.The HPV vaccine is most effective when given between the ages of 9 and 15, before any potential exposure to the virus. “Girls in this age group require only two doses of the vaccine, given six months apart,” says Dr. Meena.Dosing Schedule in Preteens: Two shots, spaced six months apart, are advised for 9–14 years.Young Adults and Late VaccinationIf an individual is missed during the suggested vaccination window during their teens, they can still get the HPV vaccine through age 45. The efficacy does drop somewhat in those who could have been exposed to some of the strains of HPV.Yes, but the effectiveness may be lower. “Women can receive the vaccine until the age of 45, but by then, they may have already been exposed to certain HPV strains,” explains Dr. Meena. Dosing Schedule for Ages 15–45: Three doses are needed over a six-month span.Do Boys and Men Need HPV Vaccination?HPV cancers are not merely a women's health issue. HPV can lead to penile, anal, throat, and oropharyngeal cancers in men. Men can also pass HPV to their partners and develop cervical cancer. The vaccine is also vital for males to ensure HPV non-transmission and reduce their own cancer risks.Dr. Meena emphasizes, "Absolutely. HPV doesn’t just affect women. Men can also develop cancers related to HPV, such as penile, anal, and oropharyngeal (throat) cancers. Vaccination in males offers the same protective benefits, preventing both cancer and the spread of the virus"Does the HPV Vaccine Have an Impact Hormones?Another prevalent parent concern is if the HPV vaccine disrupts puberty or hormone equilibrium. Doctor specialists affirm that the HPV vaccine won't change puberty or regulate hormones in any capacity. Its role is purely to activate the body's defense to identify and eliminate HPV infection.A common myth is that the HPV vaccine disrupts puberty or causes hormonal imbalances. This is false. “The HPV vaccine does not alter hormonal levels or delay puberty,” clarifies Dr. Meena. “It may cause mild side effects like redness, rash, fever, or pain at the injection site, but it does not interfere with normal growth or development.”Similar to the majority of vaccines, the HPV injection has some minor Side Effects, which include:Injection pain or sorenessSlight feverWeakenessMild dizziness or headacheSevere reactions to the vaccine are very uncommon, so it is a safe vaccine for all but a small percentage of individuals.HPV Vaccine vs. Pap Smear and HPV TestAlthough the HPV vaccine inhibits cancers associated with HPV, routine Pap tests and HPV testing are screening processes employed to diagnose precancerous or cancerous cervical changes. Many people wonder if getting the vaccine means they can skip routine cervical screenings. The answer is no.“The HPV vaccine prevents cervical cancer, while Pap smears and HPV testing are screening methods to detect early signs of cancer or precancerous lesions,” explains Dr. Meena. Even vaccinated individuals should undergo regular screenings once they become sexually active, as these tests help catch potential abnormalities early for timely treatment.Pap Smear (Cervical Screen): Detects abnormal cervical cells before they are cancerous.HPV Testing: Identifies the presence of high-risk HPV types that can cause cancer.Even after vaccination, routine cervical screening is still necessary for early detection and prompt treatment of any abnormality.Is HPV Vaccination a Lifesaving Choice?HPV-related cancers are preventable, and the vaccine is a powerful tool in that fight. Whether you're a parent deciding for your child, a teen considering immunization, or an adult wondering if it's still worth getting vaccinated, the answer is clear: the HPV vaccine offers life-saving protection.For parents, it can be a matter of preplanning their children's long-term health by assuring that the HPV vaccine is given to them. For adults, it is never too late to bring up the issue of HPV vaccination with a physician and find out if immunization can still provide protective effects.Dr. Monika Meena is a Senior Consultant Gynae Oncology and Robotic Surgeon at Apollo Cancer Centre, Kolkata in India