A new study published in the Journal of Occupational and Environment Medicine has found evidence that working excessively long hours could in fact alter the physical structure of the brain. The research was conducted by scientists from Chung-Ang University and Yonsei University in South Korea. The research offers a rare glimpse into how chronic overwork may affect not just one's mental wellbeing, but also alter the brain anatomy, What Does The Study Say?In South Korea, the legal maximum weekly working hours is 52. However, overwork there has become a pressing public health issue. The study thus tracked 110 healthcare workers, and divided them into two groups: "overworked" - individuals who worked for 52 hours or more and "non-overworked" - individuals who worked for standard hours. The study also used a neuroimaging technique and MRI scans, where researchers were able to examine differences in gray matter between the two groups. "People who worked 52 or more hours a week displayed significant changes in brain regions associated with executive function and emotional regulation, unlike participants who worked standard hours," the researchers said in a press release.What Are The Changes Noted In Brain?The analysis also revealed that overworked individuals had notable increases in the volume of them idle frontal gyrus. This part plays a role in attention, memory and cognitive control. There were also changes observed in the insula, which is responsible for emotional processing, self-awareness and understanding social context. These changes point a biological basis for the cognitive fog, mood shifts, and emotional fatigue that is commonly reported in people who work for excessively long hours. Coauthor Joon Yul Choi from Yonsei University told CNN that these brain changes "might be at least in part, reversible" if environmental stressors like overwork are reduced—though he cautioned that a full return to baseline brain function could take time.Why Does It Matter?This research builds upon previous findings. A 2021 joint study by the World Health Organization (WHO) and the International Labour Organization (ILO) estimated that long working hours led to over 745,000 deaths annually, making overwork a leading occupational risk factor.Frank Pega, who led the WHO-ILO study, told CNN that this new research provides “important new evidence” of how long working hours “radically” impact physical health. He stressed that governments, employers, and workers need to act collectively, citing laws and policies that can protect against health risks associated with overwork.While the study’s small sample size and exclusive focus on Korean healthcare workers limit its generalizability, experts believe it opens the door to deeper exploration. Jonny Gifford, principal research fellow at the Institute for Employment Studies in the UK, told CNN that the findings "confirm some physiological reasons that working long hours affects our wellbeing."He emphasized that although the study is preliminary, its use of neurological imaging lends "powerful new evidence linking overwork with structural changes in parts of the brain involved in executive function and emotional regulation."In the words of the study’s authors, “The results underscore the importance of addressing overwork as an occupational health concern.”