On World No Tobacco Day, Dr. Sajjan Rajpurohit, Senior Director of Medical Oncology at BLK-Max Super Speciality Hospital, sheds light on how tobacco affects women differently than men. While the overall dangers of smoking are well known, Dr. Rajpurohit emphasizes the need to understand the biological, hormonal, and social dimensions that make women more vulnerable to tobacco-related diseases and challenges in quitting.Biological Differences Make Women More Sensitive to Nicotine“Women metabolize nicotine more slowly than men, which results in prolonged exposure to its harmful effects,” says Dr. Rajpurohit. This slower metabolism, combined with hormonal changes across a woman’s life—such as during menstruation, pregnancy, or menopause—can heighten nicotine’s addictive properties.For instance, estrogen, a key female hormone, may increase sensitivity to nicotine, making it harder for women to quit. “This also explains why withdrawal symptoms might be more severe in women,” he adds.Higher Risk of Certain DiseasesWomen who smoke are more susceptible to certain diseases than their male counterparts, warns Dr. Rajpurohit.Lung CancerThough men historically had higher rates of lung cancer, the gap has narrowed as more women took up smoking. “Women are not only developing lung cancer at younger ages, but they may also face more aggressive forms of the disease,” he says, pointing to biological differences in lung structure and function.Heart DiseaseSmoking significantly raises the risk of heart disease in women, especially those using hormonal contraceptives. “Smoking can cause the arteries to harden and increases the risk of heart attacks and strokes. When combined with birth control pills, the risk becomes even higher,” he explains.Reproductive and Pregnancy ComplicationsSmoking affects fertility and reproductive health. It can lead to complications such as ectopic pregnancies, miscarriage, preterm delivery, and low birth weight. “Women in their childbearing years should be especially cautious, as smoking during this period can have lasting effects on both the mother and child,” Dr. Rajpurohit stresses.He also highlights severe pregnancy-related risks like placental abruption (where the placenta detaches from the uterus) and placenta previa (when the placenta blocks the cervix), both of which can endanger maternal and fetal health.Hormonal Imbalance and Fertility IssuesNicotine disrupts hormonal balance, impacting ovulation and menstrual cycles. Women who smoke often report irregular periods and find it more difficult to conceive. “The damage is not just temporary—prolonged tobacco use can lead to long-term reproductive challenges,” says Dr. Rajpurohit.Why Women Find It Harder to QuitQuitting smoking can be a more difficult journey for women due to psychological, hormonal, and social factors.“Many women smoke to manage stress, anxiety, or depression. This emotional dependence can complicate their efforts to quit,” Dr. Rajpurohit explains. Hormonal fluctuations during the menstrual cycle can also influence cravings and mood, making it harder to resist smoking.Additionally, women may lack adequate support from family or peers. “Social encouragement plays a huge role in smoking cessation, and women often find themselves without the backing they need,” he says.To help women quit, he recommends a tailored approach involving behavioral therapy, nicotine replacement therapy (NRT), and personalized quit plans. “These strategies must take into account individual stressors, emotional needs, and social settings,” he adds.Secondhand Smoke and Societal PressuresWomen are often exposed to secondhand smoke in domestic environments, putting them at risk for the same diseases as smokers. “The dangers of passive smoking are real and can lead to respiratory illness, heart disease, and even pregnancy complications,” says Dr. Rajpurohit.He also draws attention to how societal norms and advertising have historically influenced women’s smoking behavior. “Tobacco companies once marketed cigarettes to women as symbols of empowerment and liberation. Unfortunately, this portrayal led many to underestimate the health risks,” he notes.In certain cultures, smoking among women may be normalized or not taken seriously, which further prevents intervention and support.Empowering Women Through Awareness and Support“Women face unique challenges when it comes to tobacco use, and we must address them with empathy and targeted strategies,” Dr. Rajpurohit concludes. On World No Tobacco Day, he urges women to seek help and become aware of the specific risks they face.For those struggling with tobacco addiction, he recommends consulting healthcare professionals and exploring support systems that cater specifically to women’s needs. “The goal is not just to quit but to stay tobacco-free for life,” he says.